A5022444288- Healthcare professionals’ stress and burnout
- Health disparities and outcomes
- Oral Health Pathology and Treatment
- Frailty in Older Adults
- COVID-19 and Mental Health
- Head and Neck Cancer Studies
- Autism Spectrum Disorder Research
- Cardiac Imaging and Diagnostics
- Workplace Health and Well-being
- Dental Health and Care Utilization
- COVID-19 Clinical Research Studies
- Coronary Interventions and Diagnostics
- COVID-19 and healthcare impacts
- Neonatal Respiratory Health Research
- Ancient Mediterranean Archaeology and History
- Health, psychology, and well-being
- Acute Myocardial Infarction Research
- Virology and Viral Diseases
- Advancements in Transdermal Drug Delivery
- Obstructive Sleep Apnea Research
- Noise Effects and Management
- Genetics and Neurodevelopmental Disorders
- Cervical and Thoracic Myelopathy
- Nanoparticle-Based Drug Delivery
- Neuroscience of respiration and sleep
University of Palermo
2005-2025
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2018-2024
Abstract The European healthcare sector faces a significant shortage of workers. Assessing the prevalence this issue and understanding its direct indirect determinants are essential for formulating effective recruitment programs enhancing job retention strategies physicians nurses. A multicentric cross-sectional study was conducted, involving 381 1351 nurses recruited from eight hospitals in Belgium, Netherlands, Italy, Poland. focused on assessing turnover intentions among workers based Job...
Percutaneous coronary interventions (PCI) of chronic total occlusions (CTO) have reached high procedural success rates thanks to dedicated equipment, evolving techniques, and worldwide adoption state-of-the-art crossing algorithms.
Multiple factors can fuel nurses' intention to leave their employing hospital or profession. Job dissatisfaction and burnout are contributors this decision. Sociodemographic work context also play a role in explaining leave.
Introduction . The management of bisphosphonate-related osteonecrosis the jaw (BRONJ), with no evidence-based guidelines, remains controversial. We aimed to evaluate efficiency a conservative surgical treatment combining Er,Cr:YSGG laser and platelet-rich plasma (PRP) for BRONJ in cancer patients. Methods performed longitudinal cohort study. Inclusion criteria were (1) age ≥ 18 years; (2) diagnosis; (3) NBP because underlying cancer. Results consecutively recruited ten patients diagnosed...
Background/Objectives: Stroke is a leading cause of mortality and disability worldwide, ranking as the second most common death third in disability-adjusted life-years lost. Ischaemic stroke, which constitutes majority cases, poses significant public health economic challenges. This study evaluates trends ischaemic stroke hospitalisations Italy from 2008 to 2022, focusing on differences before after COVID-19 pandemic. Methods: We analysed among individuals admitted through emergency services...
Background: Gastrointestinal bleeding (GIB) is a common complication of left ventricular assist device (LVAD) support. The UTAH risk score (UBRS) the only dedicated GIB prediction model, but its efficacy has not been confirmed in an external validation cohort. Furthermore, reliability other scores, such as ARC-HBR and HASBLED, never tested this specific population. This study aims to validate UBRS compare accuracy with HASBLED scores. Methods: Major adverse events (MAEs) 75 consecutive...
With the ageing population, equitable access to medical care has proven be paramount for effective and efficient management of all diseases. Healthcare can hindered by cost barriers drugs or exams, long waiting lists difficult place where needed healthcare service is provided. The aim this paper investigate whether probability facing one these varies among individuals with different socio-economic status needs, controlling geographical variability.
Solid lipid nanoparticles (SLNs) containing tamoxifen, a nonsteroidal antiestrogen used in breast cancer therapy, were prepared by microemulsion and precipitation techniques. Tamoxifen loaded SLNs seem to have dimensional properties useful for parenteral administration, vitro plasmatic drug release studies demonstrated that these systems are able give prolonged of the intact form. Preliminary study antiproliferative activity vitro, carried out on MCF-7 cell line (human cells), SLNs,...
It is well known that self-perceived health (SPH), even if it a subjective indicator, significantly associated with objective and quality of life (QoL) in the general population. Whether can be considered an indicator cognitive functioning elderly still open issue. This study used data-driven approach to investigate interrelationship among SPH, non-communicable diseases (NCDs), QoL, answer this question. The sample included information about 12,831 people living Italy, Spain, Greece,...
Background: The relationship between Alzheimer’s disease (AD) and periodontitis has been recently investigated with heterogenous results. Objective: This study aims to evaluate the oral health status its cognitive impairment of participants, enrolled in Zabút Aging Project, a community-based cohort performed rural community Sicily, Italy. Methods: A case-control (20 subjects AD, 20 amnestic mild [aMCI], controls) was conducted. protocol included comprehensive medical cognitive-behavioral...
Healthcare organizations worldwide face challenges in retaining their healthcare workforce, with individual and organizational factors influencing intentions to leave. This study conducted eight online co-creation workshops four Delphi sessions gain qualitative in-depth insights into job retention interventions, involving workers, hospital managers, policymakers. A thematic analysis was conducted, resulting multiple interventions that were clustered pre-defined themes: professional personal...
Abstract Summary: Several samples of polymeric micelles, formed by amphiphilic derivatives PHEA, obtained grafting into backbone PEGs and/or hexadecylamine groups (PHEA‐PEG‐C 16 and PHEA‐C ) containing different amount Tamoxifen, were prepared. All Tamoxifen‐loaded micelles showed to increase drug water solubility. TEM studies provided evidence the formation supramolecular core/shell architectures drug, in nanoscopic range with spherical shape. Samples encapsulated Tamoxifen subjected vitro...
To date, there are very few epidemiologic studies on caries disease in 6-7 year old children living Sicily (Southern Italy). The first permanent molar (FPM) is the most commonly affected tooth this target population, and a one-unit increase number of decayed FPMs predictive other teeth adulthood. primary aim research to estimate prevalence schoolchildren Palermo and, as secondary aim, FPMs. It was designed cluster cross-sectional survey 995 from 16 schools, selected based their geographical...
Background: Cranio-facial anomalies frequently occur in neurodevelopmental disorders because both face and brain are derived from neuroectoderm. The identification of differences the facial phenotype children with Autism Spectrum Disorders (ASD) may reflect alterations embryologic development ASD. Methods: we evaluated 33 caucasian ASD using a 2D computerized photogrammetry. Anthropometric euclidean measurements landmarks located on soft tissue head, were based five cranio-facial indexes....
Recently, the synaptic proteins neurogranin (Ng) and α-synuclein (α-Syn) have attracted scientific interest as potential biomarkers for dysfunction in neurodegenerative diseases. In this study, we measured CSF Ng α-Syn concentrations patients affected by AD (n = 69), non-AD disorders (n-AD 50) non-degenerative (n-ND, n 98). The of were significantly higher than n-AD n-ND. Moreover, Aβ42/Ng Aβ42/α-Syn ratios showed statistically significant differences between groups discriminated from...
Literature on the association between sarcopenia and cognitive impairment is largely unclear limited to non-European populations. Therefore, aim of this study explore if presence at baseline could increase risk in a large cohort older people participating English Longitudinal Study Ageing (ELSA), over ten years follow-up. Sarcopenia was diagnosed as having low handgrip strength skeletal muscle mass index baseline, using prediction model; function evaluated ELSA through several tests. The...
(1) Aim: To assess the attitude toward Lifestyle Medicine and healthy behaviours among students in healthcare area to demonstrate its association psychological well-being; (2) Methods: A cross-sectional study is conducted 508 undergraduates of University Palermo (140 (27.6%) 368 (72.4%) non-healthcare area), during academic year 2018-2019. Psychological well-being measured through two dimensions eudaimonia hedonia, using 10-item Hedonic Eudaimonic Motives for Activities-Revised (HEMA-R)...
Obstructive sleep apnoea syndrome (OSAS) is the most severe condition on spectrum of sleep-related breathing disorders (SRBDs). The Paediatric Sleep Questionnaire (PSQ) one used and validated screening tools, but it lacks comprehensive assessment some determinants OSAS, specifically anamnestic quality. This study aims to assess accuracy specific items added original PSQ, particularly related patient’s history quality sleep, for OSAS in a paediatric population living Sicily (Italy). Fifteen...
Abstract Objective Multiple sclerosis (MS) is a complex disorder in which environmental and genetic factors interact modifying disease risk course. This multicentre, case–control study involving 18 Italian MS Centres investigated course by ethnicity native-country economic status foreign-born patients living Italy. Methods We identified 457 who migrated to Italy 893 age- sex-matched native-born patients. In our population, 1225 (93.2%) subjects were White Europeans Northern Americans (WENA)...
Adrenal insufficiency (AI) is characterized by increased mortality compared to general population, mainly due cardiovascular disease. Conventional glucocorticoid (GC) replacement therapy has a role in determining the risk. Primary outcome of current study was evaluate impact 10 years conventional GCs and DR-HC on body weight changes treatment-naive patients with AI. Secondary outcomes were from baseline 5 anthropometric metabolic profile, insulin sensitivity, cardiovascular, bone parameters.