A5011600177- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Pregnancy and preeclampsia studies
- COVID-19 Impact on Reproduction
- Global Maternal and Child Health
- Maternal Mental Health During Pregnancy and Postpartum
- Emergency and Acute Care Studies
- COVID-19 and healthcare impacts
- Ectopic Pregnancy Diagnosis and Management
- Neonatal Respiratory Health Research
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Systems and Practices
- Trauma and Emergency Care Studies
- Global Health Care Issues
- Health disparities and outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Infant Development and Preterm Care
- Pregnancy and Medication Impact
- Healthcare Systems and Challenges
- HIV, Drug Use, Sexual Risk
Istituto Superiore di Sanità
2015-2024
Istituto Nazionale di Statistica
2022-2024
National Centre for Disease Prevention and Control
2018-2021
Leiden University Medical Center
2021
Ministero della Salute
2020
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2020
Zadig (Italy)
2020
University of Catania
2020
Centre for Global Health Research
2020
European Science Foundation
2012
Abstract Objective: To describe policies towards family visiting in Neonatal Intensive Care Units (NICU) and compare findings with those of a survey carried out 10 years earlier. Methods: A questionnaire on early developmental care practices was mailed to 362 units eight European countries (Sweden, Denmark, the UK, Netherlands, Belgium, France, Spain Italy). Of them 78% responded, among 175 reported caring for at least 50 very low birth weight infants every year their responses were analysed...
Objective The primary aim of this article was to describe SARS‐CoV‐2 infection among pregnant women during the wild‐type and Alpha‐variant periods in Italy. secondary compare impact virus variants on severity maternal perinatal outcomes. Design National population‐based prospective cohort study. Setting A total 315 Italian maternity hospitals. Sample 3306 with confirmed within 7 days hospital admission. Methods Cases were prospectively reported by trained clinicians for each participating...
Objective: To compare, in a large representative sample of European neonatal intensive care units, the policies and practices regarding parental involvement holding babies kangaroo position as well differences tasks mothers fathers are allowed to carry out. Design: Prospective multicenter survey. Setting: Neonatal units eight countries (Belgium, Denmark, France, Italy, The Netherlands, Spain, Sweden, United Kingdom). Patients: Patients were not involved this study. Interventions: None....
Abstract Introduction The study was implemented to provide guidance decision-makers and clinicians by describing hospital care offered women who gave birth with confirmed COVID-19 infection. Materials methods National population-based prospective cohort involving all between February 25 April 22, 2020 in any Italian hospital. Results incidence rate of SARS-CoV-2 infection 2.1 per 1000 maternities at a national level 6.9/1000 the Lombardy Region. Overall one third developed pneumonia 49.7%...
Peripartum hysterectomy is a surgical procedure performed for severe obstetric complications such as major hemorrhage. The prevalence of peripartum in high-resource settings relatively low. Hence, international comparisons and studying indications associations with mode birth rely on the use national survey data. Objectives were to calculate its association cesarean section rates nine European countries.We descriptive, multinational, population-based study among women who underwent...
Abstract BACKGROUND: Holoprosencephaly (HPE) is a developmental field defect of the brain that results in incomplete separation cerebral hemispheres includes less severe phenotypes, such as arhinencephaly and single median maxillary central incisor. Information on epidemiology HPE limited, both because few population‐based studies have been reported, small must observe greater number years order to accumulate sufficient numbers births for reliable estimate. METHODS: We collected data from...
Accurate estimates and reliable classification of maternal deaths are imperative steps in the chain actions targeted at reducing avoidable mortality. The aims this study were to estimate mortality ratio (MMR) 10 Italian regions covering 77% total national births identify most suitable approach classify causes death.Deaths during within 1 year after pregnancy have been identified through linkage between death registry hospital discharge database. Regional data sources from 2006 2012 used. MMR...
Abstract Introduction Spontaneous hemoperitoneum in pregnancy is defined as a sudden non‐traumatic intraperitoneal bleeding and up to 42 days postpartum. In the present study we aim estimate incidence investigate risk factors, management outcomes of spontaneous order improve its clinical identification reduce avoidable maternal deaths. Material methods This prospective population‐based cohort study, set maternity units from nine Italian regions covering 75% national births. The population...
Background/Objectives: The increasing incidence of cancer during pregnancy is a growing public health concern, driven by delayed parenthood and rising maternal age. Pregnancy-associated (PAC) presents complex clinical challenges, necessitating balance between treatment fetal safety. Historically considered incompatible with favorable outcomes, evidence now suggests that can often proceed without affecting prognosis. A 2022 study in Italy provided the first population-based PAC estimates...
Abstract Introduction Peripartum hysterectomy is usually undertaken in cases of life‐threatening obstetric hemorrhage to prevent the death mother. Near‐miss events are still under‐researched and inappropriate care continues be a critical issue, even countries with advanced surveillance systems. The aim present study was estimate prevalence, associated factors, management intraoperative postoperative complications peripartum due hemorrhage. Material methods A prospective population‐based has...
Drug consumption during pregnancy is a matter of concern, especially regarding drugs known or suspected to be teratogens. Little about drug use in pregnant women Italy. The present study aimed at examining the prevalence, and detect potential inappropriateness prescribing among Latium, region central Italy.This retrospective was conducted on cohort aged 18-45 years who delivered between 2008 2012 public hospitals. Women were enrolled through Regional Birth Register. After linking regional...
The new coronavirus emergency spread to Italy when little was known about the infection’s impact on mothers and newborns. This study aims describe extent which clinical practice has protected childbirth physiology preserved mother–child bond during first wave of pandemic in Italy. A national population-based prospective cohort performed enrolling women with confirmed SARS-CoV-2 infection admitted for any Italian hospital from 25 February 31 July 2020. All cases were prospectively notified,...
Introduction Placenta accreta spectrum (PAS) is a rare but potentially life-threatening event due to massive hemorrhage. previa and previous cesarean section are major risk factors for PAS. Italy holds one of the highest rates primary repeated in Europe; nonetheless, there paucity high-quality Italian data on The aim this paper was estimate prevalence PAS evaluate its associated factors, ante- intra-partum management, perinatal outcomes. Also, since severe morbidity mortality show...
Background: In Italy, during the first epidemic wave of 2020, peak coronavirus disease 2019 (COVID-19) mortality was reached at end March. Afterward, a progressive reduction observed until much lower figures were summer, resulting from contained circulation SARS-CoV-2. This study aimed to determine if and how pathological patterns individuals deceased COVID-19 changed phases waves in terms of: (i) main cause death, (ii) comorbidities, (iii) complications related death. Methods: Death...
Monitoring severe acute maternal morbidity (SAMM) appears essential for optimising care and informing health policies, especially given changes in obstetric practices mother profiles. International comparisons can identify areas where improvement is needed, but the comparability of indicators must be evaluated.To assess feasibility monitoring SAMM using common definitions from hospital discharge databases across Europe.We used data eight countries (2 826 868 deliveries) to women with among...
To describe the Italian Obstetric Surveillance System (ItOSS) investigating maternal death through incident case reporting and confidential enquiries.All deaths occurred in any public private health facility 8 regions covering 73% of national births have been notified to ItOSS. Every is confidentially reviewed assess quality care establish cause avoidability death.A total 106 among 1 455 545 live surveillance system 2013-17. Haemorrhage, sepsis hypertensive disorders pregnancy are leading...
This study aimed to estimate the incidence of SARS-CoV-2 infection among pregnant women during first pandemic wave in Italy, and describe COVID-19 disease characteristics maternal perinatal outcomes.National population-based prospective cohort collecting information on with diagnosis, confirmed within 7 days from hospital admission.The national rate was 6.04 per 1,000 births (95% CI 5.62-6.49) 7.54 7.47-7.61) reproductive age. 72.1% developed mild without pneumonia nor need for ventilatory...
The aim of this study is to describe the frequency and trend pregnancy-associated cancer (PAC) in Italy, an increasingly relevant phenomenon due postponing age at childbirth. To purpose, a population-based retrospective longitudinal design based on cohorts women aged 15-49 diagnosed with concomitant pregnancy proposed. uses 19 Cancer Registries, covering about 22% linked individual level Hospital Discharge Records. A total 2,861,437 pregnancies 3559 PAC are identified from 74,165 cohort rate...
Deficiency of folic acid (FA) has been identified as a risk factor for neural tube defects (NTDs) well other congenital anomalies. Thus, periconceptional folate supplementation is recommended all women planning to get pregnant.We conducted KAP (knowledge, attitude, practice) survey investigate the use FA and its appropriateness. The included sample 562 who delivered in Lazio region between 2013 2014. Two logistic regression analyses were performed evaluate association characteristics...
Background: Endometriosis is a female chronic inflammatory disease in which endometrial tissue develops outside the uterine cavity. It complex pathology, that significantly contributes to morbidity premenopausal women, leading pain, infertility, and subfertility negatively impacting physical, emotional well-being overall quality of life. The public health burden endometriosis remains elusive challenging determine, this uncertainty can lead inadequate healthcare services treatments....