Xiaodan Zhang

ORCID: 0000-0003-4760-1260
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Research Areas
  • Traditional Chinese Medicine Analysis
  • Microbial Metabolism and Applications
  • Natural product bioactivities and synthesis
  • Phytochemicals and Antioxidant Activities
  • Phytochemistry and Biological Activities
  • Metabolomics and Mass Spectrometry Studies
  • Phytoestrogen effects and research
  • Microencapsulation and Drying Processes
  • Essential Oils and Antimicrobial Activity
  • Mycorrhizal Fungi and Plant Interactions
  • Tea Polyphenols and Effects
  • Pharmacological Effects of Medicinal Plants
  • Food Drying and Modeling
  • Phytochemical compounds biological activities
  • Drug Transport and Resistance Mechanisms
  • Plant-based Medicinal Research
  • Pharmacogenetics and Drug Metabolism
  • Ginseng Biological Effects and Applications
  • Fermentation and Sensory Analysis
  • Bioactive Compounds in Plants
  • Fungal Biology and Applications
  • NF-κB Signaling Pathways
  • Traditional Chinese Medicine Studies
  • Botanical Research and Chemistry
  • Proteins in Food Systems

Nantong University
2025

Zhejiang Sci-Tech University
2017-2024

Henan University of Science and Technology
2023-2024

South China Agricultural University
2022

Shanghai CASB Biotechnology (China)
2022

Lanzhou University
2022

Institute of Soil and Water Conservation
2018

Ministry of Water Resources of the People's Republic of China
2018

Northwest A&F University
2014

Chung-Ang University
2012

Introduction Tetrastigma hemsleyanum Diels et Gilg is a medicinal plant known for its diverse pharmacological effects, including anti-inflammatory, anti-tumor, anti-hepatocellular carcinoma, and antipyretic activities. To explore the components from different parts of to fully utilize T. , this study investigated mechanisms underlying differential accumulation metabolites in tuberous roots, fibrous leaves. Methods This employed combination metabolomics transcriptomics analyze metabolic...

10.3389/fpls.2025.1478061 article EN cc-by Frontiers in Plant Science 2025-04-02

To better understand the mechanisms underlying pharmacological actions of Salvia miltiorrhiza, correlation between chemical profiles and in vitro antioxidant activities 50 batches wild S. miltiorrhiza samples was analyzed. Our ultra-performance liquid chromatography–tandem mass spectrometry analysis detected twelve phenolic acids five tanshinones obtained various from different origins. In a principal component (PCA) cluster analysis, cryptotanshinone, tanshinone IIA dihydrotanshinone I...

10.3390/molecules23030538 article EN cc-by Molecules 2018-02-28

The study investigated the effects of different microwave vacuum freeze-drying powers (100-500 W) on emulsifying properties and structural characteristics egg white protein, which is great significance in enhancing added value EWP promoting its application. Emulsification analysis revealed that emulsification performance was significantly influenced by power reached maximum at 300 W. Fourier-transform infrared spectroscopy (FT-IR) sodium dodecyl sulfate-polyacrylamide gel electrophoresis...

10.3390/foods12091792 article EN cc-by Foods 2023-04-26

Sasanquasaponin (SQS), a secondary metabolite that is derived from Camellia seeds, reportedly possesses notable biological properties. However, the anti-inflammatory effects of SQS and its underlying mechanisms remain poorly explored. Herein, we aimed to investigate properties against lipopolysaccharide (LPS)-induced inflammatory responses in RAW264.7 cells, focusing on nuclear factor-κB (NF-κB) MAPK signaling pathways. was isolated using deep eutectic solvent D101 macroporous adsorption...

10.3390/ijms25042149 article EN International Journal of Molecular Sciences 2024-02-10

A novel aporphine alkaloid was isolated from the leaves of Epimedium koreanum Nakai during activity-guided fractionation in search compounds with an anticholinesterase activity. The structure new compound assigned as 1,10-methoxy-7-hydroxy-aporphine (1), which we have named epimediphine. Unambiguous 1H-NMR and 13C-NMR data for epimediphine are described. Epimediphine inhibited acetylcholinesterase (AchE) activity a dose-dependent manner IC50 value 3.1 µM. Meanwhile, tacrine,...

10.1080/14786419.2012.708660 article EN Natural Product Research 2012-07-24

Objectives: The differences in chemical constituents different parts of Tetrastigma hemsleyanum were analyzed. Methods: contents total phenols, flavonoids, and polysaccharides methanol extracts from T. Zhejiang determined, the components collected by ultra-performance liquid chromatography-tandem quadrupole-time-of-flight mass spectrometry. differential index identified analyzed accurate mass-to-charge ratio primary spectrometry fragment ion secondary with reference spectrum software...

10.1177/1934578x241239494 article EN cc-by-nc Natural Product Communications 2024-05-01

In this study, ultrasonic-assisted cellulase extraction (UCE) was applied to extract flavonoids and polyphenols from the Nymphaea hybrid flower. The conditions were optimized using response surface method (RSM) coupled with a Box-Behnken design. crude of (NHE) further purified AB-8 macroporous resins, (NHEP) characterized by FTIR HPLC. vitro activity determination chemical showed that NHEP displayed strong free radical scavenging abilities against DPPH ABTS radicals, good reduction power,...

10.3390/molecules27061914 article EN cc-by Molecules 2022-03-16

Salvia mltiorrhiza Bunge (SMB) is native to China, whose dried root has been used as medicine. A few chromatographic- or spectrometric-based methods have already analyze the lipid-soluble components in SMB. However, methodology of qNMR on extracts fresh SMB not verified so far. The purpose this study was establish a fast and simple method quantify tanshinone I, IIA, dihydrotanshinone, cryptotanshinone Miltiorrhiza without any pre-purification steps using 1H-NMR spectroscopy. process follows:...

10.3390/molecules25092043 article EN cc-by Molecules 2020-04-28

Anisophyllea laurina is a plant that has been used in folk medicine to treat malaria, dysentery, diabetes, toothache and various skin diseases. Leaves extract had protein content of 9.68% high calcium 25084.317 mg/100 g while stem bark was found contain greater amounts (8560.96 g), potassium (7649.47 magnesium (1462.49 g) iron (973.33 g). Palmitic acid, linolenic linoleic acid oleic were the most abundant fatty acids leaves extracts. Furthermore, total phenolic (2382.39 mg GAE /100 flavonoid...

10.1590/s2175-97902017000216040 article EN cc-by Brazilian Journal of Pharmaceutical Sciences 2017-01-01

Lilium leucanthum is popularly used as one of the ornamental lily plant and medicinal bulbs in its local distribution areas with a long history China. The aim this study was to provide sufficient experimental evidence for further utilisation wild L. source natural antioxidants. Total phenolic content antioxidant activity three ecotypes from Zhenping, Zhouqu Liuba County China P.R. were determined using method Folin-Ciocalteau 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity,...

10.3920/qas2013.0256 article EN Quality Assurance and Safety of Crops & Foods 2014-09-04

The main objective of the current study was to investigate components and antioxidant activity essential oil extracted from Purple Eleutherococcus leaves (identified as simonii) (PEEO) by hydrodistillation (HD) solid-phase microextraction (SPME). Fourteen chemical were identified in PEEO using gas chromatography-mass spectrometry (GC-MS), accounting for 41.21% total SPME, including isopropyl toluene, 4-methylene-1-(1-methylethyl) cyclohexene (3.24%), fumaric-red myrrh alcohol (2.94%),...

10.1590/fst.76821 article EN Food Science and Technology 2021-10-20

Background:: Tetrastigma hemsleyanum (THL) is a traditional medicinal plant with various biological activities, it has been validated that several THL extracts have strong pharmacological activities. Until now, there no complete and systematic germplasm identification quality evaluation standard. Objective:: Establishing fingerprint spectra of from different sources, evaluating their antioxidant activity identifying markers. Methods:: In this paper, establishing fingerprints markers through...

10.2174/0122103155301912240228080042 article EN The Natural Products Journal 2024-03-05

Abstract Introduction The plant essential oils are composed of volatile compounds and have significant value in preventing treating neurological diseases, anxiety, depression, among others. genus S alvia has been shown to be an important medicinal resource, especially the aerial parts Salvia , which rich compounds; however, chemical diversity distribution patterns species still unknown. Objective work is performed analyse . Methods genomic single nucleotide polymorphisms (SNPs) combined with...

10.1002/pca.3306 article EN Phytochemical Analysis 2023-12-19

Altricial birds often display biased preferences in providing parental care for their dependent offspring, especially during food shortages. During this process, such inflexible rules may result provisioning errors. To demonstrate how parents optimize strategies, we proposed a "diagnosis model" of to posit that will undergo diagnosis procedure test whether selecting against some particular offspring based on phenotype is an optimal strategy. We tested model asynchronous hatching bird, the...

10.1093/cz/zoac064 article EN cc-by-nc Current Zoology 2022-08-17

Background and Objective: Radix Salvia miltiorrhiza (RSM) has been used clinically for the prevention treatment of cardiovascular diseases; therefore, it is important to strengthen its quality management. Considering multiple constituents when assessing RSM essential. We established a simple, rapid method identify quantify major bioactive in using ultra high performance liquid chromatography (UPLC) coupled triple quadruple mass spectrometry (QqQ-MS). Methods: analyzed 17 markers from 50...

10.2174/1573412914666181105144418 article EN Current Pharmaceutical Analysis 2018-11-06

Background: Although chromatography and spectrometry-based methods have been used to analyse phenolic acids in Chinese traditional medicine Salvia miltiorrhiza Bunge (SMB), quantitative nuclear magnetic resonance (qNMR) has never previously fresh SMB root extracts. Objective: To establish a fast simple method of quantitating danshensu, lithospermic acid, rosmarinic salvianolic acid B content using 1 H-NMR spectroscopy. Method: Fresh was extracted 70% methanol aqueous solution quantitatively...

10.2174/1573412916666191231104909 article EN Current Pharmaceutical Analysis 2019-12-31

Quantification monitoring of 74 samples Polygalae Radix collected from Korean and China was conducted following the analysis method Chinese Pharmacopoeia (CP) 2015 edition. However, this is considered not accuracy enough because tenuifolin chosen to be only marker component for quality control Radix. The de-sugar products onjisaponins oligosaccharide esters including tenuifolin(1), 3,4,5-trimethoxycinnamic acid(2), 4-methoxy cinnamic acid methyl ester(3) were isolated alkaloid hydrolysis...

10.17480/psk.2017.61.4.227 article EN Yakhak Hoeji 2017-07-20
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