Lei Zhang

ORCID: 0000-0003-0809-5836
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About
Contact & Profiles
Research Areas
  • Insect Resistance and Genetics
  • Insect-Plant Interactions and Control
  • Insect Pest Control Strategies
  • CRISPR and Genetic Engineering
  • Insect and Arachnid Ecology and Behavior
  • Insect and Pesticide Research
  • Genomics and Phylogenetic Studies
  • Genetic diversity and population structure
  • Entomopathogenic Microorganisms in Pest Control
  • Lepidoptera: Biology and Taxonomy
  • Plant Molecular Biology Research
  • Insect symbiosis and bacterial influences
  • Chromosomal and Genetic Variations
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant Taxonomy and Phylogenetics
  • Epigenetics and DNA Methylation
  • Physiological and biochemical adaptations
  • Photosynthetic Processes and Mechanisms
  • interferon and immune responses
  • Insect Utilization and Effects
  • Neurobiology and Insect Physiology Research
  • 14-3-3 protein interactions
  • Genomics and Chromatin Dynamics
  • Phytochemistry and Bioactive Compounds
  • Genomics, phytochemicals, and oxidative stress

Agricultural Genomics Institute at Shenzhen
2019-2025

Chinese Academy of Agricultural Sciences
2015-2025

Ministry of Agriculture and Rural Affairs
2022-2025

Zhejiang Sci-Tech University
2023-2024

Institute of Special Animal and Plant Sciences
2020-2024

Ludong University
2023

Fudan University
2016-2023

Huazhong University of Science and Technology
2022-2023

Harbin Medical University
2022-2023

Shanghai Jiao Tong University
2022-2023

The process of plant domestication is often protracted, involving underexplored intermediate stages with important implications for the evolutionary trajectories traits. Previously, tomato history has been thought to involve two major transitions: one from wild Solanum pimpinellifolium L. a semidomesticated intermediate, S. lycopersicum var. cerasiforme (SLC) in South America, and second transition SLC fully domesticated Mesoamerica. In this study, we employ population genomic methods...

10.1093/molbev/msz297 article EN cc-by-nc Molecular Biology and Evolution 2019-12-13

Abstract The rapid wide‐scale spread of fall armyworm ( Spodoptera frugiperda ) has caused serious crop losses globally. However, differences in the genetic background subpopulations and mechanisms adaptation behind invasion are still not well understood. Here we report assembly a 390.38‐Mb chromosome‐level genome derived from south‐central Africa using Pacific Bioscience (PacBio) Hi‐C sequencing technologies, with scaffold N50 12.9 Mb containing 22,260 annotated protein‐coding genes....

10.1111/1755-0998.13219 article EN cc-by Molecular Ecology Resources 2020-07-03

Polycomb repressive complexes (PRCs) play crucial roles in transcriptional repression and developmental regulation both plants animals. In plants, depletion of different members PRCs causes overlapping unique phenotypic defects. However, the underlying molecular mechanism determining target specificity functional diversity is not sufficiently characterized. Here, we quantitatively compared changes tri-methylation at H3K27 Arabidopsis mutants deprived various key PRC components. We show that...

10.1371/journal.pgen.1005771 article EN cc-by PLoS Genetics 2016-01-13

Abstract The discovery of fall armyworm, a native the Western Hemisphere, in western Africa 2016 was rapidly followed by detections throughout sub-Saharan Africa, India, and most recently southeastern Asia. This moth pest has broad host range that threatens such important crops as corn, rice, millet, sorghum, creating concern for its potential impact on agriculture Eastern Hemisphere. Although genetic data suggest populations sampled India originate from recent common source, it is not known...

10.1038/s41598-020-58249-3 article EN cc-by Scientific Reports 2020-01-29

Tumor-reactive CD8+ tumor-infiltrating lymphocytes (TILs) represent a subtype of T cells that can recognize and destroy tumor specifically. Understanding the regulatory mechanism tumor-reactive has important therapeutic implications. Yet DNA methylation status this cell not been elucidated.In study, we segregate bystander TILs, as well naïve effector memory subtypes controls from colorectal cancer patients, to compare their transcriptome methylome characteristics. Transcriptome profiling...

10.1186/s13059-019-1921-y article EN cc-by Genome biology 2019-12-31

The element contents of wheat from four major wheat-producing regions China were analyzed and used in multivariate statistical analysis to classify according geographical origin. concentrations 15 elements (Be, Na, Mg, Al, K, Ca, V, Mn, Fe, Cu, Zn, Mo, Cd, Ba, Th) 240 samples the 2007/2008 2008/2009 harvests determined by inductively coupled plasma mass spectrometry. variance linear discriminant applied origin, effects region, variety, harvest year on this study. It was concluded that...

10.1021/jf200108d article EN Journal of Agricultural and Food Chemistry 2011-04-06

The major plant pest fall armyworm (FAW), Spodoptera frugiperda, is native to the Americas and has colonized Africa Asia within Eastern hemisphere since 2016, causing severe damage multiple agricultural crop species. However, genetic origin of these invasive populations requires more in-depth exploration. We analysed variation across genomes 280 FAW individuals from both Americas. global range-wide structure shows that in America experienced deep differentiation, largely consistent with...

10.1111/mec.17117 article EN cc-by-nc-nd Molecular Ecology 2023-08-28

Abstract Bacillus thuringiensis ( Bt ) crops expressing Vip3Aa are highly efficacious in controlling major lepidopteran pests and delaying evolution of pest resistance. Although practical resistance to the field has not been reported, proactively manage resistance, there is an urgent need better understand genetic basis Vip3Aa. This particularly important for fall armyworm Spodoptera frugiperda ), one most destructive around world, which evolved crystal (Cry) toxins. Here, a Vip3Aa-resistant...

10.1101/2024.02.18.580648 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-20

The nonrandom three-dimensional organization of chromatin plays an important role in the regulation gene expression. However, it remains unclear whether this is conserved and involved regulating expression during speciation after whole-genome duplication (WGD) plants. In study, high-resolution interaction maps were generated using high-throughput conformation capture (Hi-C) techniques for two poplar species, Populus euphratica alba var. pyramidalis, which diverged ~14 Mya a common WGD. We...

10.1038/s41438-021-00494-2 article EN cc-by Horticulture Research 2021-03-10

Abstract Understanding the genetic basis of pest adaptive evolution and risk adaptation in response to climate change is essential for development sustainable agricultural practices. However, climatic Asian corn borer (ACB), Ostrinia furnacalis, main Asia Oceania, poorly understood. Here, we revealed genomic loci underlying ACB by integrating population environmental factors. We assembled a 471-Mb chromosome-scale reference genome resequenced 423 individuals covering 27 representative...

10.1093/molbev/msad112 article EN cc-by-nc Molecular Biology and Evolution 2023-05-01

Energy and food source crop demand claims to be vulnerable climate change impacts. The new orphan crops, which in the past have received only limited research attention but are sustainable environmental systems, needed. In this review, we summarize available literature about Ethiopian mustard as an alternative energy its economic importance a promising Brassicacea for opportunities face of producing environment development. has many advantages can adopted replace crops that susceptible...

10.3390/su12187492 article EN Sustainability 2020-09-11

The oriental armyworm, Mythimna separata, poses a persistent challenge to agricultural pest management due its strong migratory abilities and polyphagous feeding behavior. In this study, we present chromosome-level genome assembly using Illumina, PacBio HiFi, Hi-C sequencing technologies. final spans 714.5 Mb with scaffold N50 of 22.7 GC content 38.8%. A total 32 chromosomes were successfully anchored, including the Z W sex chromosomes. BUSCO analysis indicated completeness 98.6%, 19,879...

10.1038/s41597-025-04855-7 article EN cc-by-nc-nd Scientific Data 2025-03-31

A novel endophytic bacterium, strain ZYY112T, isolated from rice roots, was characterized by a polyphasic approach. In phylogenetic analyses based on 16S rRNA gene sequences, ZYY112T showed highest sequence similarity to Novosphingobium sediminicola HU1-AH51T (97.2 %) and less than 97 % with respect other species validly published names. The DNA G+C content of 60.8 mol%. level DNA–DNA relatedness between N. DSM 27057T 33.7 (reciprocal 5.2 %), which supported the suggestion that represented...

10.1099/ijsem.0.000718 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2015-10-29

Abstract The rapid wide-scale spread of fall armyworm ( Spodoptera frugiperda ) has caused serious crop losses globally. However, differences in the genetic background subpopulations and mechanisms adaptation behind invasion are still not well understood. Here we report a 393.25-M chromosome-level genome assembly with scaffold N50 13.3 M consisting 23281 annotated protein-coding genes. Genome-wide resequencing 105 samples from 16 provinces China revealed that population comprises complex...

10.1101/813154 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2019-10-21

Abstract In migratory insects, increasing evidence has demonstrated juvenile hormone (JH) is involved in regulating adult reproduction and flight. Our previous study that the switch from migrants to residents Mythimna separata could be induced by adverse environmental conditions during a sensitive period adulthood (the first day post-emergence), but role of JH this not clear. Here, we found significantly different pattern titers between residents, with showing slower release than residents....

10.1038/s41598-020-66973-z article EN cc-by Scientific Reports 2020-07-15

The insecticidal Vip3 proteins, secreted by Bacillus thuringiensis (Bt) during its vegetative growth phase, are currently used in Bt crops to control insect pests, and genetically distinct from known Cry proteins. Compared with toxins, the mechanisms of toxins still poorly understood. Here, responses Spodoptera frugiperda larvae after Vip3Aa challenge characterized. Using an integrative analysis transcriptomics proteomics, we found that has enormous implications for various pathways....

10.3390/toxins14010055 article EN cc-by Toxins 2022-01-13

Abstract The fall armyworm (FAW), Spodoptera frugiperda , has colonized and caused consistent damage in the Eastern hemisphere. identification of various FAW strains is essential for developing precise prevention control measures. triosephosphate isomerase ( Tpi ) gene recognized as an effective marker closely linked to subpopulations. However, most current studies primarily focus on comparison variations specific sites this gene. In study, we conducted full‐length sequencing genes from 5...

10.1111/1744-7917.13348 article EN Insect Science 2024-02-27

Leaf heading is an important and economically valuable horticultural trait in many vegetables. The formation of a leafy head specialized leaf morphogenesis characterized by the emergence enlarged incurving leaves. However, transcriptional regulation mechanisms underlying transition to remain unclear. We carried out large-scale time-series transcriptome assays covering major vegetative growth phases two headingBrassica crops, Chinese cabbage cabbage, with non-heading morphotype Taicai as...

10.1111/tpj.15695 article EN The Plant Journal 2022-02-04

Physiological management of migration-reproduction trade-offs in energy allocation often includes a package adaptions referred to as the oogenesis-flight syndrome. In some species, this trade-off may be overestimated, because factors like flight behavior and environmental conditions mitigate it. study, we examined reproductive consequences induced by different scenarios an economically-important Asian migrant insect, Cnaphalocrocis medinalis. We found that influences on reproduction are not...

10.1371/journal.pone.0121821 article EN public-domain PLoS ONE 2015-03-27
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