A5072715994- Plant biochemistry and biosynthesis
- Plant Gene Expression Analysis
- Plant Molecular Biology Research
- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Analysis
- Photosynthetic Processes and Mechanisms
- Ginseng Biological Effects and Applications
- Sesquiterpenes and Asteraceae Studies
- Biochemical and biochemical processes
- Polysaccharides and Plant Cell Walls
- Plant Disease Resistance and Genetics
- Seed Germination and Physiology
- Plant Stress Responses and Tolerance
- Computational Drug Discovery Methods
- Fungal Biology and Applications
- Allelopathy and phytotoxic interactions
- Biological Activity of Diterpenoids and Biflavonoids
- Tea Polyphenols and Effects
- Plant Water Relations and Carbon Dynamics
- Transgenic Plants and Applications
- Biological and pharmacological studies of plants
- Phytochemistry and Biological Activities
- Phytochemistry and Bioactive Compounds
- Ethnobotanical and Medicinal Plants Studies
- Chemical synthesis and alkaloids
Zhejiang Sci-Tech University
2012-2024
Northwest A&F University
2012-2024
Institute of Soil and Water Conservation
2019-2020
Ministry of Water Resources of the People's Republic of China
2020
Agriculture and Forestry University
2012
NTL Institute for Applied Behavioral Science
2010
University of Mississippi
2009
Salvia miltiorrhiza has been widely used in the treatment of coronary heart disease. Tanshinones, a group diterpenoids are main active ingredients S. miltiorrhiza. Two biosynthetic pathways were involved tanshinone biosynthesis plants: mevalonate (MVA) pathway cytosol and methylerythritol phosphate (MEP) plastids. The 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) is rate-limiting enzyme MVA pathway. 1-deoxy-D-xylulose 5-phosphate synthase (DXS) reductoisomerase (DXR) key enzymes MEP...
Abstract Salvia miltiorrhiza and S. grandifolia are rich in diterpenoids have therapeutic effects on cardiovascular diseases. In this study, the spatial distribution of both species was analyzed by a combination metabolomics mass spectrometry imaging techniques. The results indicated that were mainly abietane-type norditerpenoid quinones with furan or dihydrofuran D-ring distributed periderm roots, e.g. cryptotanshinone tanshinone IIA. compounds phenolic tricyclic six- seven-membered...
Abstract Climate change profoundly influences the geospatial distribution of secondary metabolites and causes geographical migration plants. We planted seedlings same species in eighteen ecological regions along a latitudinal gradient eastern western China, order to explore regulation multi-climatic factors on active ingredient accumulation Salvia miltiorrhiza Bunge. The correlations between six contents ten climatic were investigated clarify their relationships. found that not only...
Abstract DNA methylation plays a crucial role in the regulation of plant growth and biosynthesis secondary metabolites. Danshen (Salvia miltiorrhiza) is valuable Chinese herbal medicine commonly used to treat cardiovascular diseases; its active ingredients are tanshinones phenolic acids, which primarily accumulate roots. Here, we conducted targeted metabolic analysis S. miltiorrhiza roots at 3 distinct stages: 40 d old (r40), 60 (r60), 90 (r90). The contents (cryptotanshinone, tanshinone I,...
Pinellia ternata (Thunb.) is a famous traditional Chinese medicine with high medicinal value, but its culture strongly hindered by the continuous cropping obstacles (CCO) which are tightly associated allelopathic effects. Deciphering response mechanisms of P. to allelochemicals critical for overcoming CCO. Here, we elucidate phenolic acids treatment via physiological indices, cellular approaches, and transcriptome analysis. Phenolic showed significant effect on growth seedlings, similar...
Sasanquasaponin (SQS), a secondary metabolite that is derived from Camellia seeds, reportedly possesses notable biological properties. However, the anti-inflammatory effects of SQS and its underlying mechanisms remain poorly explored. Herein, we aimed to investigate properties against lipopolysaccharide (LPS)-induced inflammatory responses in RAW264.7 cells, focusing on nuclear factor-κB (NF-κB) MAPK signaling pathways. was isolated using deep eutectic solvent D101 macroporous adsorption...
Sakuranetin, a flavonoid phytoalexin in rice, plays crucial role defense against pathogen infection. While MYB-type transcription factors are well-known to regulate plant growth, development, secondary metabolism, and adaptation environmental stresses, the function of rice MYB-related sakuranetin biosynthesis sakuranetin-mediated remains unclear. In this study, we identified characterized OsMYB1R, novel single repeat MYB factor that acts as transcriptional activator biosynthesis. Protein-DNA...
Radix bupleuri is one of the bulk medicinal materials in China and it widely adopted clinical applications drug discovery. The investigation agronomic traits, active component content genetic diversity diverse germplasms may provide evidence to promote selection better strains. In this research, 13 from various sources were used investigate variations between different germplasms. Nine biological characteristics noted field, levels two primary ingredients determined using high performance...
Abstract Danshen, a prominent herb in traditional Chinese medicine (TCM), is known for its potential to enhance physiological functions such as blood circulation, immune response, and resolve stasis. Despite the effectiveness of COVID-19 vaccination efforts, some individuals still face severe complications post-infection, including pulmonary fibrosis, myocarditis arrhythmias stroke. This study employs network pharmacology molecular docking approach investigate mechanisms underlying...
MicroRNAs (miRNAs) are a class of non-coding RNAs that play critical roles in post-transcriptional regulation. Their target genes involved variety biological processes such as development, metabolism, and stress response. Panicum miliaceum L. (Panicum) is an important grain crop, but, until now, no miRNAs have been identified this plant. Using homology search based on expressed sequence tag (EST) analysis miRNA precursor secondary structure, total 43 new were identified. The found to be...
Although several microsatellite markers of Smilax aspera (Smilacaceae) have been reported in a previous study, due to universality issues cross-population amplification, we newly developed for S. based on transcriptome data further investigate gene flow and genetic structure its circum-Mediterranean, East African, South Asian populations.A total 4854 simple sequence repeat (SSR) primer pairs were designed from 99,193 contigs acquired public bona-nox. Forty-six loci selected genotyping 12...
The investigation focuses on medicinal plants knowledge among ethnic populations in Shaanxi Province, China. Province is well known for its rich plant diversity and groups, but no ethnobotanical study has been conducted up to now. Field work was from 2008 2009, using the methods of informant depiction, semi-structured interviews informal discussions obtain traditional local residents specialist. 94 species belonging 86 genera 46 families were used treat various daily diseases populations. 19...
To fully explore the influence mechanism of interactions between different monomer units proanthocyanidins (PAs) on biological activity, a path analysis model PA structure-activity relationship was proposed. This subdivides total correlation each unit and activity into direct indirect effects by taking account not only but also with its related units. In addition, this method can determine action mode affecting comparing effects. Finally, advantage is demonstrated through an Rhodiola...