A5100766096- Protein Hydrolysis and Bioactive Peptides
- Genomics and Phylogenetic Studies
- Estrogen and related hormone effects
- bioluminescence and chemiluminescence research
- Healthcare and Venom Research
- Aquaculture disease management and microbiota
- Viral Infectious Diseases and Gene Expression in Insects
- Physiological and biochemical adaptations
- Plant and Fungal Species Descriptions
- Chemical Synthesis and Analysis
- Genomics, phytochemicals, and oxidative stress
- Neuroscience of respiration and sleep
- Synthesis and Biological Evaluation
- High Altitude and Hypoxia
- GDF15 and Related Biomarkers
- Steroid Chemistry and Biochemistry
- Adipose Tissue and Metabolism
- Antimicrobial Peptides and Activities
- Cancer therapeutics and mechanisms
- Plant Disease Resistance and Genetics
- Synthetic Organic Chemistry Methods
- Invertebrate Immune Response Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer-related molecular mechanisms research
- Biosensors and Analytical Detection
Institute of Apiculture Research
2024
China Medical University
2022
Second Affiliated Hospital of Zhejiang University
2017-2022
Central South University of Forestry and Technology
2021
Central South University
2021
Hengshui University
2021
Zhejiang Sci-Tech University
2017-2018
Yangzhou University
2011-2016
Wuhan Institute of Virology
2016
Chinese Academy of Sciences
2016
Food-derived bioactive peptides are considered as the important sources of natural ingredients. Approximately 3094 were identified by nESI-LC-MS/MS in hydrolyzed yak milk residue. Peptide KALNEINQF (T10) is strongest antioxidant peptide. The damage model H2O2-induced human umbilical vein endothelial cells (HUVECs) was used to evaluate effect. After treatment with 25, 50, or 100 μg/mL T10 peptide, obviously decreased and increased cell survival. Comparing group, superoxide dismutase (SOD)...
Wu, Tianyi, Shouquan Ding, Jinliang Liu, Jianhou Jia, Ruichen Dai, Baozhu Liang, Jizhui Zhao, and Detang Qi. Ataxia: an early indicator in high altitude cerebral edema. High Alt. Med. Biol. 7:275–280, 2006.—As a result of industrial development the western region China, 2001 Chinese government decided to build Qinghai–Tibetan Railway. The new railroad stretches 1118 km from Golmud (2808 m) Lhasa (3658 m), with more than three-quarter distance above 4000 m, through Mt. Kun Lun Tanggula...
<h3>Rationale</h3> The relationship between cigarette smoking and acute mountain sickness (AMS) is not clear. <h3>Objective</h3> To assess AMS risk altitude acclimatisation in relation to smoking. <h3>Methods</h3> 200 healthy non-smokers 182 smokers were recruited from Han lowland workers. These men without prior exposure, matched for age, health status occupation, who transported an of 4525 masl. <h3>Measurements</h3> AMS, habits, arterial saturation (SpO<sub>2</sub>), haemoglobin (Hb),...
Glioma is the most common primary intracranial malignant tumor in brain. Currently, due to limited treatment methods, clinical outcome of patients with standard surgery combined radiotherapy and chemotherapy not satisfactory. Therefore, we urgently need develop effective drugs solve this problem. As a semisynthetic derivative artemisinin, dihydroartemisinin (DHA) has been proved have antitumor activity glioma, which can induce apoptosis inhibit proliferation, migration, invasion glioma...
Studies have shown that the peroxidation caused by oxygen free radicals is an important reason of vascular endothelial dysfunction and multiple diseases. In this study, active peptides (F2ds) were isolated from fermentation product rice dregs its antioxidant effects approved. Human umbilical vein cells (HUVECs) stimulated H 2 O used to evaluate antioxidation effect molecular mechanism in oxidative stress model. F2d protected ‐induced damage HUVECs a dosage‐dependent manner. can reduce...
Interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α and prostaglandins E2 is considered as the standard cocktail for maturing dendritic cells (DCs). However, appropriate time span DC maturation with remains unclear. The present study aimed to compare differences between DCs matured 24 48 h, respectively, determine whether 24-h stimulation was sufficient maturation. findings demonstrated that, compared levels of cluster differentiation (CD)80, CD83, CD86 programmed death-ligand 1...
Although several microsatellite markers of Smilax aspera (Smilacaceae) have been reported in a previous study, due to universality issues cross-population amplification, we newly developed for S. based on transcriptome data further investigate gene flow and genetic structure its circum-Mediterranean, East African, South Asian populations.A total 4854 simple sequence repeat (SSR) primer pairs were designed from 99,193 contigs acquired public bona-nox. Forty-six loci selected genotyping 12...
An eco-friendly efficient method was developed for the synthesis of abiraterone acetate and analogues in water-PEG-400 (6:1; v/v) at 75°C from various arylboronic acids 17-(trifluoromethanesulfonyl)oxy-3β-acetoxylandrosta-5,16-diene obtained 3-acetate dehydroepiandrosterone.
Paenibacillus sp. strain A9 is an important bioflocculant-producing bacterium, isolated from a soil sample, and pale pink-pigmented, aerobic, Gram-positive. Here, we report the draft genome sequence initial findings preliminary analysis of A9, which novel species Paenibacillus.
An efficient preparation of hydroxysteroids by a one-pot, simultaneously rapid deprotection 3-acyloxy groups and reduction D-ring ketones (nitrile) steroids using DIBAL-H in the presence NiCl 2 (10 mol %) is described. The attractive features this procedure for hydroxysteroid derivatives are mild reaction conditions, short time, excellent yields, clean profiles, an inexpensive catalyst system.
In this study, 26 candidate genes were quantified and normalized in the brain cDNA of common carp (Cyprinus carpio) at 23°C 6°C using double-standard curve method real-time quantitative PCR. The results showed that five candidates up-regulated samples (P<0.01) 2.11, 13.9, 2.52, 7.38, 1.83 times more than 23°C, respectively. Gene function searching indicated protein products these elongation very long chain fatty acids protein, Acyl-CoA desaturase, Transcription initiation factor IIB,...
As a common defense mechanism in Hymenoptera, bee venom has complex components. Systematic and comprehensive analysis of components can aid early evaluation, accurate diagnosis, protection organ function humans cases stings. To determine the differences composition metabolic pathways between Apis cerana mellifera, proton nuclear magnetic resonance (
Expressed sequence tags (ESTs) are parts of complementary DNAs (cDNAs) with certain gene function.It provides us more information than other neutral markers. The association EST markers with phenotypes can increase our understanding the biochemical pathways and mechanisms affecting economically important traits. In this study, 12 candidate EST isolated from cold-induced brain cDNA common carp (Cyprinus carpio L.) were conducted correlation analysis marker and cold tolerance trait carp using...
Tricyrtis (Liliaceae) is an endemic genus in East Asia. Many of the species are Endangered condition due to habitat loss and extensive horticultural usage recent decades. In present study, we reported first chloroplast (cp) genome, macropoda, based on Illumina pair-end sequencing data. The complete genome size 155,778 bp. total, 131 genes were identified, including 85 protein-coding genes, 8 rRNA 38 tRNA genes. Fifteen containing introns (clpP ycf3 contained two introns) 14 had copies....
During the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) trial, patients with hypertension who received amlodipine had similar cardiovascular risks as those candesartan. We conducted a post-trial study, 10-year follow-up (CASE-J 10). This study aimed to confirm long-term effects of candesartan and amlodipine.Case report forms were sent CASE-J investigators agreed participate 10. All available information was retrospectively collected. The primary endpoint time-to-first...