- Genetic Mapping and Diversity in Plants and Animals
- Plant Molecular Biology Research
- Rice Cultivation and Yield Improvement
- GABA and Rice Research
- Photosynthetic Processes and Mechanisms
- Plant Stress Responses and Tolerance
- Plant nutrient uptake and metabolism
- Plant Gene Expression Analysis
- Genomics and Phylogenetic Studies
- Plant responses to water stress
- Plant Reproductive Biology
- Nanoplatforms for cancer theranostics
- Plant Genetic and Mutation Studies
- Food composition and properties
- Plant-Microbe Interactions and Immunity
- Polysaccharides and Plant Cell Walls
- Aluminum toxicity and tolerance in plants and animals
- Plant tissue culture and regeneration
- Biofuel production and bioconversion
- Nanoparticle-Based Drug Delivery
- Chromosomal and Genetic Variations
- Mitochondrial Function and Pathology
- Genetics and Plant Breeding
- Plant Disease Resistance and Genetics
- CRISPR and Genetic Engineering
China National Rice Research Institute
2016-2025
Chinese Academy of Agricultural Sciences
2015-2025
Suzhou Vocational Health College
2017-2024
Donghua University
2023-2024
Guizhou Electric Power Design and Research Institute
2020-2024
Jiangsu University
2024
Zhejiang Chinese Medical University
2024
Wenzhou Medical University
2024
Ohio University
2019-2024
Hangzhou Medical College
2024
More than half of the world's population uses rice as a source carbon intake every day. Improving grain quality is thus essential to consumers. The three main properties that determine eating and cooking quality--amylose content, gel consistency, gelatinization temperature--correlate with one another, but underlying mechanism these remains unclear. Through an association analysis approach, we found genes related starch synthesis cooperate each other form fine regulating network controls...
Detection of early malignant tumors remains clinically difficult; developing ultrasensitive imaging agents is therefore highly demanded. Owing to the unusual magnetic and optical properties associated with f-electrons, rare-earth elements are very suitable for creating functional materials potentially useful tumor imaging. Nanometer-sized particles offer such a platform which versatile unique can be integrated. Yet development nanoparticle-based probes tiny in vivo difficult, challenges not...
Abstract The indica and japonica rice ( Oryza sativa ) subspecies differ in nitrate (NO 3 − assimilation capacity nitrogen (N) use efficiency (NUE). Here, we show that a major component of this difference is conferred by allelic variation at OsNR2 , gene encoding NADH/NADPH-dependent NO reductase (NR). Selection-driven divergence has resulted variant alleles structurally distinct proteins, with exhibiting greater NR activity. Indica also promotes uptake via feed-forward interaction OsNRT1.1B...
A tumor microenvironment responsive nanoprobe is developed for enhanced imaging through in situ crosslinking of the Fe3 O4 nanoparticles modified with a peptide sequence which tumor-specific Arg-Gly-Asp targeting and self-peptide as "mark self" are linked disulfide bond. Positioning at outmost layer aimed delaying clearance from bloodstream. After cleaved by glutathione within microenvironment, exposed thiol groups react remaining maleimide moieties adjacent particles to crosslink situ. Both...
A better understanding of transcriptional evolution IDH-wild-type glioblastoma may be crucial for treatment optimization. Here, we perform RNA sequencing (RNA-seq) (n = 322 test, n 245 validation) on paired primary-recurrent resections patients treated with the current standard care. Transcriptional subtypes form an interconnected continuum in a two-dimensional space. Recurrent tumors show preferential mesenchymal progression. Over time, hallmark genes are not significantly altered. Instead,...
Significance Hybrid rice developed in China has been contributing greatly to the world’s food production. The pioneer super hybrid by crossing 93–11 and Peiai 64s , Liang–You–Pei–Jiu widely grown other Asia-Pacific regions for its high yield. Here, quality genome sequences both parental lines were presented updated, a high-resolution map of genome-wide graphic genotypes was constructed deep resequencing core population 132 recombinant inbred lines. A series yield-associated loci fine-mapped,...
The basic premise of high yield in rice is to improve leaf photosynthetic efficiency and coordinate the source–sink relationship plants. Quantitative trait loci (QTLs) related morphological traits chlorophyll content leaves were detected at stages heading maturity, a major QTL (qLSCHL4) flag shape was both recombinant inbred lines constructed using indica cultivar 93-11 japonica Nipponbare. Map-based cloning expression analysis showed that LSCHL4 allelic NAL1, gene previously reported narrow...
Understanding the genetic basis of natural variation in grain size among diverse rice varieties can help breeders develop high-yielding cultivars. Here, we report discovery qTGW2, a new semidominant quantitative trait locus for width and weight. The corresponding gene, TGW2, encodes CELL NUMBER REGULATOR 1 (OsCNR1) localized to plasma membrane. A single nucleotide polymorphism (SNP) 1818 bp upstream TGW2 is responsible its different expression, leading alteration weight by influencing cell...
A protease-activated ratiometric fluorescent probe based on fluorescence resonance energy transfer between a pH-sensitive dye and biocompatible Fe3O4 nanocrystals was constructed. peptide substrate of MMP-9 served as linker the particle quencher chromophore that covalently attached to antitumor antibody. The optical response activated gastric cell line SGC7901 tumor cells investigated, followed by in vivo imaging. Based pH microenvironment, resulting successfully used image subcutaneous xenografts.
Drought is one of the environmental factors that severely restrict plant distribution and crop production. Recently, we reported high-affinity potassium transporter OsHAK1 plays important roles in K acquisition translocation rice over low high concentration ranges, however, knowledge on regulatory osmotic/drought stress limited. Here, transcript levels were found transiently elevated by water deficit roots shoots, consistent with enhanced GUS activity transgenic plants under stress. Under...
Abstract Rice is a major source of cadmium (Cd) intake for Asian people. Indica rice usually accumulates more Cd in shoots and grains than Japonica rice. However, underlying genetic bases differential accumulation between are still unknown. In this study, we cloned quantitative trait locus (QTL) grain C d c oncentration on chromosome 7 ( GCC7 ) responsible two varieties by performing QTL analysis map‐based cloning. We found that the alleles, PA64s 93‐11 , had different promoter activity...
Bacterial blight (BB) is a globally devastating rice disease caused by Xanthomonas oryzae pv. (Xoo). The use of resistance (R) genes in breeding an effective and economical strategy for the control this disease. Nevertheless, majority R lack durable long-term under global warming conditions. Here, we report isolation novel executor gene, Xa7, that confers extremely durable, broad-spectrum, heat-tolerant to Xoo. expression Xa7 was induced incompatible Xoo strains secreted transcription...
Summary Lesion‐mimic mutants (LMMs) provide a valuable tool to reveal the molecular mechanisms determining programmed cell death (PCD) in plants. Despite intensive research, behind PCD and formation of lesions various LMMs still remain be elucidated. Here, we identified rice ( Oryza sativa ) LMM, early lesion leaf 1 ell1 ), cloned causal gene by map‐based cloning, verified this complementation. ELL1 encodes cytochrome P450 monooxygenase, protein was located endoplasmic reticulum. The mutant...
Summary Plant architecture and stress tolerance play important roles in rice breeding. Specific leaf morphologies ideal plant can effectively improve both abiotic resistance grain yield. However, the mechanism by which plants simultaneously regulate morphogenesis remains elusive. Here, we report that SRL10 , encodes a double‐stranded RNA‐binding protein, regulates morphology thermotolerance through alteration of microRNA biogenesis. The srl10 mutant had semi‐rolled phenotype elevated...
Carotenoid isomerase activity and carotenoid content maintain the appropriate tiller number, photosynthesis, grain yield. Interactions between strigolactone abscisic acid pathways regulates formation. Tillers are unique inflorescence-like branches in grasses, their number determines panicle plant architecture, yield (Shang et al., 2021). Tiller formation mainly undergoes axillary meristem (AM) initiation bud outgrowth (Wang 2018; Yan 2023). The rice (Oryza sativa) KNOX gene OSH1 is expressed...
Gelatinization temperature (GT) is an important parameter in evaluating the cooking and eating quality of rice. Indeed, phenotype, biochemistry inheritance GT have been widely studied recent times. Previous map-based cloning revealed that was controlled by ALK gene, which encodes a putative soluble starch synthase II-3. Complementation vector RNAi were constructed transformed into Nipponbare mediated Agrobacterium. Phenotypic molecular analyses transgenic lines provided direct evidence for...