Xiaohong Huang

ORCID: 0000-0003-4809-4010
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About
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Research Areas
  • Protein Hydrolysis and Bioactive Peptides
  • Toxoplasma gondii Research Studies
  • Biofuel production and bioconversion
  • Aquaculture disease management and microbiota
  • Enzyme Production and Characterization
  • Invertebrate Immune Response Mechanisms
  • Herpesvirus Infections and Treatments
  • Bacteriophages and microbial interactions
  • Polyamine Metabolism and Applications
  • Phytase and its Applications
  • Parasitic Infections and Diagnostics
  • Protist diversity and phylogeny
  • Anaerobic Digestion and Biogas Production
  • melanin and skin pigmentation
  • Microbial infections and disease research
  • Toxin Mechanisms and Immunotoxins
  • COVID-19 diagnosis using AI
  • Vector-borne infectious diseases
  • Probiotics and Fermented Foods
  • MicroRNA in disease regulation
  • Mycotoxins in Agriculture and Food
  • AI in cancer detection
  • Antimicrobial Peptides and Activities
  • Radiomics and Machine Learning in Medical Imaging
  • Immune Cell Function and Interaction

Beijing University of Posts and Telecommunications
2009-2025

Second Affiliated Hospital of Nanchang University
2025

Nanchang University
2025

Affiliated Hospital of North Sichuan Medical College
2025

Fujian Agriculture and Forestry University
2012-2024

Fujian Normal University
2010-2023

State Key Laboratory of Information Photonics and Optical Communications
2023

Sichuan Agricultural University
2020-2022

Chinese Academy of Tropical Agricultural Sciences
2017-2020

Fujian University of Traditional Chinese Medicine
2020

Large-scale breeding environments often lead to oxidative stress. Macrophages play an important role in the immune system and are vulnerable reactive oxygen species (ROS), which result macrophage death. Curcumin is main active component of turmeric exerts antioxidant effects. Here, we measured activity some enzymes chose Nrf2-Keap1 signaling pathway study protective effects curcumin on macrophages under stress vitro. We used RAW264.7 cells as a research model, damage was induced by hydrogen...

10.1371/journal.pone.0216711 article EN cc-by PLoS ONE 2019-05-21

We evaluated the effects of different oxidation levels lipids on protein degradation and biogenic amines (BAs) formation during Sichuan-style sausages processing. Lipids with varying degrees were obtained through storage at temperatures added as raw materials sausages, followed by analyses lipid oxidation, degradation, amine content, other indicators. During processing, increasing degree contents peroxide value (POV), thiobarbituric acid reactive substances (TBARs), index (PI), amino...

10.1016/j.lwt.2022.113344 article EN cc-by-nc-nd LWT 2022-03-11

This study presents a novel Semantic-Attention Enhanced Dynamic Swin Convolutional Block Attention Module(CBAM) Transformer (DSC-Transformer) for lymph node ultrasound image classification. The model integrates semantic feature extraction and multi-scale attention mechanisms with the architecture, enabling efficient processing of diagnostically significant regions while suppressing noise. Key innovations include semantic-driven preprocessing localized diagnostic focus, adaptive compression...

10.3390/bioengineering12020190 article EN cc-by Bioengineering 2025-02-16

Mucin 17 (MUC17), a transmembrane mucin, is overexpressed in pancreatic cancer and associated with tumor proliferation metastasis. CD3 an indispensable molecule on the surface of T lymphocytes, which cell activation participates immune responses. Here, we developed bispecific T-cell engager radiotracer, 89Zr-M17C3, targeting MUC17 CD3, to enable noninvasive PET imaging both cells infiltration cancer. 89Zr-M17C3 was synthesized by conjugating AMG199 zirconium-89 verified for its radiochemical...

10.1021/acs.molpharmaceut.5c00072 article EN Molecular Pharmaceutics 2025-03-27

Orf virus (ORFV), a species of the genus Parapoxvirus family Poxviridae, causes nonsystemic, highly contagious and eruptive disease in sheep, goat, other wild domestic ruminants. Our previous work shows orf to be ubiquitous Fujian Province China, region where there is considerable heterogeneity among ORFVs. In this study, we sequenced full genomes four goat ORFV strains (OV-GO, OV-YX, OV-NP OV-SJ1). The were 132 139 kb length, with each containing 124 genes about 64% G+C content. most...

10.3389/fmicb.2015.01135 article EN cc-by Frontiers in Microbiology 2015-10-23

Abstract Nuclear factor κB (NF-κB) plays an essential role in regulation of innate immunity. In mammals, NF-κB factors can form homodimers and heterodimers to activate gene expression. insects, three factors, Dorsal, Dif Relish, have been identified antimicrobial peptide (AMP) However, it is not clear whether Dorsal (or Dif) Relish heterodimers. Here we report the identification functional analysis a homologue (MsDorsal) two short isoforms (MsRel2A MsRel2B) from tobacco hornworm, Manduca...

10.1038/srep20654 article EN cc-by Scientific Reports 2016-02-05

Babesia ovata is a tick-transmitted hemoprotozoan parasite that infects cattle. In our study, bovine blood samples (n=2,034) were collected from 10 different countries (Brazil, China, Ghana, Japan, Mongolia, the Philippines, South Africa, Sri Lanka, Thailand and Vietnam) DNA extracted. The screened using an established specific polymerase chain reaction (PCR) assay targeting Apical membrane antigen 1 (AMA-1) gene. Parasite was detected among Mongolia Thailand. Sequence analyses confirmed PCR...

10.1292/jvms.12-0329 article EN cc-by-nc-nd Journal of Veterinary Medical Science 2012-10-03

The argasid tick Ornithodoros moubata is a vector of various viral and borrelian diseases in animals humans. We report here molecular characterization oligosaccharide-binding properties novel galectin (OmGalec) from this tick. OmGalec consisted 333 amino acids with predicted weight 37.4 kDa. Its acid sequence did not contain signal peptide or transmembrane domain. It possessed tandem-repeated carbohydrate recognition domains, which the typical motifs important for affinity were conserved....

10.1093/glycob/cwl070 article EN cc-by-nc Glycobiology 2006-11-23

Cellulases are produced by microorganisms that grow on cellulose biomass. Here, a cellulase, Cel10, was identified in strain of Klebsiella pneumoniae isolated from Chinese bamboo rat gut. Analysis substrate specificity showed Cel10 is able to hydrolyze amorphous carboxymethyl (CMC) and crystalline forms (Avicel xylan) but unable p -nitrophenol β-D-glucopyranoside ( -NPG), proving an endoglucanase. A phylogenetic tree analysis indicates belongs the glycoside hydrolase 8 (GH8) subfamily. In...

10.1107/s2053230x16017891 article EN cc-by Acta Crystallographica Section F Structural Biology Communications 2016-11-25

The surface antigen 1-related sequence 2 of Neospora caninum (NcSRS2) is considered as an immunodominant antigen. In this study, the gene encoding truncated NcSRS2 (NcSRS2t) lacking N-terminal signal peptide and C-terminal hydrophobic regions was expressed in Escherichia coli, its diagnostic potential enzyme-linked immunosorbent assay (ELISA) evaluated. ELISA could discriminate clearly between known N. caninum-positive -negative sera from cattle. Field serum samples collected cattle Brazil...

10.1645/ge-267r1 article EN Journal of Parasitology 2005-02-01

To minimize environmental contamination and waste of resources, distillers' grain (DG) from the Chinese liquor industry was used to produce reducing sugars for Bacillus thuringiensis cultivation. Four different pretreatments, using sodium hydroxide (0.5–2% w/v, 50–121 °C, 1 h), calcium (0.2–4% dilute sulfuric acid hot water (50–121 were investigated in order determine optimal method degrading cellulose DG monomeric sugars. Enzymatic hydrolysis fermentation followed each pretreatment method....

10.1021/acs.energyfuels.5b00250 article EN Energy & Fuels 2015-05-27

Lignocellulose is considered a renewable organic material, but the industrial production of biofuel from lignocellulose challenging because lack highly active hydrolytic enzymes. The guts herbivores contain many symbiotic microorganisms that have evolved to hydrolyze plant lignocellulose. Chinese bamboo rats mainly consume high-fiber foods, indicating some members intestinal tract microbiota digest lignocellulose, providing these with energy required for growth. Here, we used metagenomics...

10.1016/j.ejbt.2020.12.001 article EN cc-by-nc-nd Electronic Journal of Biotechnology 2020-12-30
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