This study aimed to compare microbial and inflammatory profiles in periodontally/systemically healthy African American (AA) Caucasian (C) individuals.

ABSTRACT Aim The clinical outcomes of a variety surgical procedures highly depend on tissue repair and show high variability among patients. There is gap in the literature how host inflammatory response, microbiome, interplay between them can influence oral mucosa healing. In this pilot study, we aimed to evaluate microbiome biomarkers profiles patients who had desired versus undesired wound healing palatal mucosa. Methods Seventeen underwent free gingival graft (FGG) for socket...

Abstract Background This study was conducted to assess the clinical, immunological, and patient‐centered outcomes of microcurrent electrotherapy on palatal wound healing. Methods a parallel, double‐masked randomized clinical trial, in which 53 patients with ridge preservation indications were selected randomly assigned one two groups. In control (sham) group (n = 27), wounds, after free gingival grafts (FGG) harvest, received sham application electrotherapy. test (electrotherapy treatment...

Abstract Background In the present study, we aim to assess a novel silk‐fibroin (SF) chitosan (CH) film treat oral mucosa wounds. Methods The SF/CH films, sterilized with 130 Gy in gamma cell, were subjected tests for thickness, water vapor permeability, tensile strength, elongation, and swelling as well scanning electron microscopy. Additionally, vitro cytotoxicity genotoxicity evaluated using human epidermal keratinocytes, foreskin fibroblasts, gingival fibroblasts. A pilot clinical trial...

This study evaluates the antimicrobial activity of glycolic extract G. sylvestre against anaerobic pathogens, along with its cytotoxicity, genotoxicity, anti-inflammatory activity, antioxidant effects, and phytochemical composition. Phytochemical analysis was conducted using high-performance liquid chromatography chromatography-mass spectrometry, while effect assessed through a DPPH assay. Antimicrobial action tested on planktonic cultures biofilms Porphyromonas gingivalis, endodontalis,...

Abstract Background The use of omega‐3 (Ω‐3) polyunsaturated fatty acids and acetylsalicylic acid (ASA, aspirin) has shown better clinical outcomes in the treatment periodontitis compared to nonsurgical periodontal therapy (NSPT) alone. This randomized trial aimed evaluate 900 mg Ω‐3 100 ASA for 180 days as adjuncts NSPT generalized stage III–IV grade C (GCP). Methods Patients underwent subgingival debridement (SD) associated with Ω‐3+ASA or cellulose placebo received monthly prophylaxis....

The literature lacks long-term evidence regarding outcomes of the coronally advanced tunnel flap (TUN) combined with connective tissue graft (CTG) when compared to trapezoidal (CAF) and CTG combination. This study presents 2-year results a randomized clinical trial comparing either CAF or TUN in treatment single maxillary gingival recession (GR) defects.Thirty-nine patients, each contributing Miller Class I II GR defect, were treated by CAF+CTG (control; n = 19) TUN+CTG (test; 20) completed...

Abstract Background This study aimed to compare a connective tissue graft (CTG) (porcine) xenogeneic acellular dermal matrix (XDM), both associated with modified coronally advanced flap (MCAF) and partial resin composite restoration treat multiple combined defects (CDs). Methods Seventy‐eight in 38 patients presenting defects, that is, gingival recession non‐carious cervical lesions, were treated by (apical margin up 1 mm of the estimated cement‐enamel junction) MCAF along CTG or XDM. After...

Abstract Background This study was conducted to evaluate the clinical, immunologic, and patient‐centered outcomes of enamel matrix protein derivative (EMD) on excisional wounds in palatal mucosa. Materials Forty‐four patients need ridge preservation were randomly allocated into two groups: control group ( n = 22): open wound after free gingival graft (FGG) harvest EMD FGG that received 0.3 ml EMD. Clinical parameters analyzed for 3 months post‐treatment. Wound fluid levels inflammatory...

Xenogeneic matrices (XMs) have been increasingly used for root coverage procedures. This study compared the use of two types XM (collagen matrix [CM] and xenogeneic acellular dermal [XDM]) associated with coronally advanced flap technique (CAF) to treat single gingival recessions.Seventy-five patients presenting RT1 recession were treated by CAF (control group, n = 25), CAF+CM (test group 1, or CAF+XDM 2, 25) completed 6-month follow-up. Clinical, patient-centered, esthetic assessments...

Abstract Objectives There are few studies comparing xenogeneic acellular dermal matrixes (XDMs) with connective tissue graft (CTG) to treat single gingival recession (GR). The present study involved a reanalysis of previous and comparison CTG or XDM RT1/GR. Materials methods Fifty patients from three randomized clinical trials treated either by ( n = 25) were evaluated after 6‐month. Clinical, patient‐centered, esthetic parameters assessed. Pearson's correlation regression analyses also...

Abstract Background Periodontal disease is a biofilm‐dependent chronic inflammatory condition triggered by host response. Several factors impact systemic inflammation and could lead to changes in pathogenesis. Recently, studies have assessed the influence of nutritional patterns on development periodontitis. In present cross‐sectional study, we evaluated dietary profile periodontal conditions, focusing clinical, subgingival microbial, cytokine assessment individuals with health or...

Gingival recession (GR) is a prevalent problem that related to esthetic demands and dentin hypersensitivity. Frequently, GR associated with non-carious cervical lesion (NCCLs) forming combined defect (CD), which requires restorative surgical treatment. Connective tissue graft procedures allow predictable root coverage but can result in patient discomfort.This first case report describes multiple GRs B+ NCCL at teeth #4 #6 of 27-year-old thin periodontal phenotype. The aim this was evaluate...

Connective tissue graft substitutes have been used widely to overcome autogenous limitations. Nevertheless, they do not provide comparable results in the treatment of periodontal and peri-implant soft defects. Based on principles tissue-engineered materials, injectable platelet-rich fibrin (i-PRF) has combined with collagen matrices (CMs) enhance their clinical efficacy. To best our knowledge, this is first case series demonstrating use i-PRF for biofunctionalization a volume-stable matrix...

The inherently technique-sensitive nature of periodontal plastic procedures demands a significant level skill and expertise. incorporation three-dimensional (3D) printing technologies emerges as potential strategy to optimize simplify surgical procedures. This case report describes the digital workflow presents clinical outcomes achieved using guided coronally advanced flap for treatment single gingival recession (GR).

INTRODUÇÃO: A deiscência do tecido mole peri-implantar (DTMP) é uma condição clínica frequente e desafiadora, que leva a preocupações biológicas estéticas. É essencial realizar um diagnóstico abordagem correta para DTMP, com foco em procedimentos protéticos mucogengivais, se alcançar manutenção implante longo prazo. OBJETIVO: O presente estudo descreve caso clínico necessidade de tratamento DTMP (Classe IV, subclasse A/Defeito Tipo I) 9,8 mm recessão vestibular (RV), mucosa fenótipo fino, área...

Collagen matrices have been used as connective tissue graft (CTG) substitutes. However, they do not the same efficacy compared to CTG. Adding biological agents may increase collagen matrices' efficacy. The present case reports use of a biofunctionalized volume-stable matrix (VCMX) with injectable platelet-rich fibrin (iPRF) associated coronally advanced flap (CAF) treat single gingival recession (GR) defect.A Recession Type 1 (RT1 A-) defect at maxillary left canine in male patient was...

This study evaluated the use of a xenogeneic acellular dermal matrix (XADM) combined with modified coronally advanced flap (MCAF) and partial resin composite filling (anatomic crown plus 1 mm root surface) to treat multiple Type gingival recessions associated B+ noncarious cervical lesions (NCCLs). The included 24 in 10 patients. Bleeding on probing, probing depth, defect height, relative recession, clinical attachment level, esthetics, dentin hypersensitivity were recorded. After 6 months,...

The use of platelet-rich fibrin (PRF) membranes has been evaluated for different purposes. However, few studies aimed to assess the effect PRF on peri-implant mucosal thickness augmentation. Thus, aim was evaluate whether placed using same surgical procedure single implant installation in anterior area maxilla can result increase.Eight patients received maxillary implants (anterior area), covered by three (2,500 rpm/12 minutes, RCFmax = 719.71 g). Clinical parameters (baseline and 3 months...

Gingival recession (GR) is a relevant clinical condition due to its high prevalence worldwide, which leads aesthetic demands and dentin hypersensitivity. Collagen matrices have been associated with different designs of coronally advanced flaps (CAFs) treat GR defects. However, the literature lacks long-term follow-up this treatment option. The aim study present (up 7 years) two defects (associated or not noncarious cervical lesion) treated CAF collagen matrix (CM).Case 1 underwent CM single...