A5000448730- Nanoparticles: synthesis and applications
- Bacterial biofilms and quorum sensing
- Antibiotics Pharmacokinetics and Efficacy
- Antifungal resistance and susceptibility
- Antimicrobial Peptides and Activities
- Antimicrobial agents and applications
- Advanced Drug Delivery Systems
- Antibiotic Resistance in Bacteria
- Inhalation and Respiratory Drug Delivery
- Photodynamic Therapy Research Studies
- Antimicrobial Resistance in Staphylococcus
- bioluminescence and chemiluminescence research
- Lipid Membrane Structure and Behavior
- Essential Oils and Antimicrobial Activity
- Advanced Nanomaterials in Catalysis
- Organometallic Compounds Synthesis and Characterization
- Metal complexes synthesis and properties
- Nanocomposite Films for Food Packaging
- Respiratory and Cough-Related Research
- Cystic Fibrosis Research Advances
- Marine Biology and Environmental Chemistry
- Bioactive Compounds and Antitumor Agents
- Graphene and Nanomaterials Applications
- Moringa oleifera research and applications
- Education in Rural Contexts
Universidad Nacional de Córdoba
2016-2025
Consejo Nacional de Investigaciones Científicas y Técnicas
2013-2025
Centro Científico Tecnológico - Córdoba
2018-2021
Instituto Multidisciplinario de Biología Vegetal
2013
United States Department of Veterans Affairs
1977
The University of Texas Health Science Center at Houston
1977
Mesoporous silica nanoparticles (MSNs) are an interesting class of nanomaterials with potential applications in different therapeutic areas and that have been extensively used as drug carriers fields medicine. The present work is focused on the synthesis MSNs containing a maleamato ligand (MSN-maleamic) subsequent coordination copper(II) ions (MSN-maleamic-Cu) for exploration their application antibacterial agents. Cu-containing characterized by techniques preliminary effect supported...
Gentamicin (GEN), a widely used broad-spectrum antibiotic, faces challenges amid the global emergency of antimicrobial resistance. This study aimed to explore synergistic effects zinc oxide nanoparticles (ZnO NPs) in combination with GEN on bactericidal activity against various bacterial strains. Results showed ZnO NPs MICs ranging from 0.002 1.5 μg/mL, while precursor salt displayed MIC range 48.75–1560 μg/mL. Chitosan (CS)-capped exhibited even lower than their uncapped counterparts,...
Currently, the biosynthesis of silver-based nanomaterials attracts enormous attention owing to documented antimicrobial properties these ones. This study reports extracellular silver nanoparticles (Ag-NPs) using a Pseudomonas aeruginosa strain from reference culture collection. A greenish supernatant P. incubated at 37°C with nitrate solution for 24 h changed yellowish brown color, indicating formation Ag-NPs, which was confirmed by UV-vis spectroscopy, transmission electron microscopy, and...
Background/Objectives: Pulmonary delivered tobramycin (TOB) is a standard treatment for Pseudomonas aeruginosa lung infections, that, along with Staphylococcus aureus, one of the most common bacteria causing recurring infections in CF patients. However, only available formulation on market containing tobramycin, TOBI®, sold at price that makes access to difficult. Therefore, this work focuses development and characterization an ionic complex between polyelectrolyte, hyaluronic acid (HA) its...
Five different silica nanoparticles functionalized with vitamin B12, a derivative of coumarin found in green plants and minimum content an organotin(IV) fragment (1-MSN-Sn, 2-MSN-Sn, 2-SBA-Sn, 2-FSPm-Sn 2-FSPs-Sn), were identified as excellent anticancer agents against triple negative breast cancer, one the most diagnosed aggressive cancerous tumors, very poor prognosis. Notably, compound 2-MSN-Sn shows selectivity for cancer cells luminescent properties detectable by imaging techniques once...
The prevalence of antibiotic resistance has resulted in the need for new approaches to be developed combat previously easily treatable infections. main aim this work was establish potential synthetic α -diimine chromium(III) and ruthenium(II) complexes (where ligands are bpy = 2,2-bipyridine, phen 1,10-phenanthroline, dppz dipyrido[3,2-a:2′,3′-c]-phenazine) like [Cr(phen) 3 ] 3+ , 2 (dppz)] [Ru(phen) 2+ [Ru(bpy) as antibacterial agents by generating oxidative stress. showed activity against...
Polyelectrolyte-drug complexes are interesting alternatives to improve unfavourable drugs properties. Vancomycin (VAN) is an antimicrobial used in the treatment of methicillin-resistant Staphylococcus aureus pulmonary infections patients with cystic fibrosis. It generally administered intravenously high incidence adverse side effects, which could be reduced by intrapulmonary administration. Currently, there no commercially available inhalable formulations containing VAN. Thus, present work...
Persister cells (PCs) make up a small fraction of microbial population, can survive lethal concentrations antimicrobial agents. In recent years, Candida tropicalis has emerged as being frequent fungal agent medical devices subject to biofilm infections. However, PCs are still poorly understood.This study aimed investigate the relation on redox status in C. biofilms exposed high doses Amphotericin B (AmB), and alterations surface topography architecture biofilms.We used an experimental model...