Rakesh Gupta

ORCID: 0000-0003-4845-6069
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About
Contact & Profiles
Research Areas
  • Cardiac Imaging and Diagnostics
  • Blood Pressure and Hypertension Studies
  • COVID-19 Clinical Research Studies
  • COVID-19 and healthcare impacts
  • Child Nutrition and Water Access
  • Cardiovascular Function and Risk Factors
  • Cardiac Valve Diseases and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Viral gastroenteritis research and epidemiology
  • COVID-19 diagnosis using AI
  • Coronary Interventions and Diagnostics
  • Sepsis Diagnosis and Treatment
  • Global Maternal and Child Health
  • Asthma and respiratory diseases
  • Pediatric Hepatobiliary Diseases and Treatments
  • Dental Research and COVID-19
  • Pancreatic and Hepatic Oncology Research
  • Breastfeeding Practices and Influences
  • Renin-Angiotensin System Studies
  • Congenital Heart Disease Studies
  • Pancreatitis Pathology and Treatment
  • Heart Failure Treatment and Management
  • Gallbladder and Bile Duct Disorders
  • Glaucoma and retinal disorders
  • Infective Endocarditis Diagnosis and Management

All India Institute of Medical Sciences Raipur
2024-2025

Central Council for Research in Yoga & Naturopathy
2024

Banaras Hindu University
2024

Institute of Medical Sciences
2013-2023

Central Drug Research Institute
2023

Indira Gandhi Medical College
2022

Gandhi Medical College & Hospital
2014-2022

McMaster University
2018-2021

M.J.P. Rohilkhand University
2019-2021

Government Dental College and Hospital
2021

Sivasubramanian Ramakrishnan Geevar Zachariah Kartik Gupta J. Shivkumar Rao Padhinhare P. Mohanan and 95 more K. Venugopal Santosh Sateesh Rishi Sethi Dharmendra Jain Neil Bardolei Kalaivani Mani Tanya Singh Kakar Bharath Raj Kidambi Sudha Bhushan Sunil Kumar Verma Balram Bhargava Ambuj Roy Shyam S. Kothari Rajeev Gupta Sandeep Bansal Sanjay Sood Ranjit Kumar Nath Sanjay Tyagi Mohit Gupta M.P. Girish Ish Kalra Gurpreet Singh Wander Satish Gupta Subroto Mandal Nagendra Boopathy Senguttuvan Geetha Subramanyam Debabatra Roy Sibananda Datta Kajal Ganguly Satya Narayan Routray Surabhi Mishra Bhaskar Singh Bhavneet Bharti Mrinal Kanti Das Soumitra Kumar Kewal C. Goswami Vinay K. Bahl Sarat Chandra Amal Kumar Banerjee Santanu Guha P.K. Deb H K Chopra Prakash Deedwania Ashok Seth J. Shivkumar Rao Bhaskar Singh Bhavneet Bharti Amit Kumar Sinha Kartik Gupta Sivasubramanian Ramakrishnan Sudha Bhushan Sunil Kumar Verma Balram Bhargava Ambuj Roy Sandeep Bansal Sanjay Sood H.S. Isser Neeraj Pandit Ranjit Kumar Nath Sanjay Tyagi Vijay Trehan Mohit Gupta M.P. Girish Ramandeep Ahuja S.C. Manchanda A. K. Mohanty Peeyush Jain Sameer Shrivastava Ish Kalra Bhakti Sarang H.S. Ratti G. Bala Sahib Rakesh Gupta S. K. Agarwal Amit Kewal C. Goswami Vinay K. Bahl H K Chopra Ashok Seth Geevar Zachariah Padhinhare P. Mohanan K. Venugopal George Koshy Tiny Nair N. D. V. N. Shyam Anil Roby Raju George Sudhaya Kumar Md. Abdul Kader Mathew Abraham Sunitha Viswanathan Jabir Abdullakutty Jaideep Menon Govindan Unni Cibu Mathew

Hypertension is the most important risk factor for cardiovascular morbidity and mortality. There limited data on hypertension prevalence in India. This study was conducted to estimate of among Indian adults. A national level survey with fixed one-day blood pressure measurement camps across 24 states union territories defined as systolic (BP) ≥140 mmHg or a diastolic BP ≥90 treatment hypertension. The age- gender-standardized according 2011 census population Blood recorded 180,335...

10.1016/j.ihj.2019.09.012 article EN cc-by-nc-nd Indian Heart Journal 2019-07-01

The rapid emergence of coronavirus disease 2019 (COVID-19) as a global pandemic affecting millions individuals globally has necessitated sensitive and high-throughput approaches for the diagnosis, surveillance, determining genetic epidemiology SARS-CoV-2. In present study, we used COVIDSeq protocol, which involves multiplex-PCR, barcoding, sequencing samples detection deciphering We approach on 752 clinical in duplicates, amounting to total 1536 could be sequenced single S4 flow cell NovaSeq...

10.1371/journal.pone.0247115 article EN cc-by PLoS ONE 2021-02-17

Of 691 healthy (untreated) villagers of Tecumseh, Michigan (average age 32.6 years), 99 had a clinical blood pressure exceeding 140/90 mmHg. Thirty-seven per cent these borderline hypertensives increased heart rate, cardiac index, forearm flow and plasma norepinephrine. These subjects elevated self-determined home 14 measurements). The present hyperkinetic borderlines at 5, 8, 21 23 years their parents also higher pressure. prevalence high in its long history, readings outside the...

10.1097/00004872-199101000-00012 article EN Journal of Hypertension 1991-01-01

Nigella sativa and its derivatives have been reported to anti-inflammatory bronchodilator effects, but the effects evaluated in only a few clinical studies.To determine effect of N supplementation on inflammation airways limitation airflow partly controlled asthma patients.Single-blind, placebo-controlled, randomized study.Asthma allergy clinic university hospital eastern Saudi Arabia.Patients were divided into three groups. A control group (n=24) received placebo, while NS-1 NS-2 groups...

10.5144/0256-4947.2017.64 article EN cc-by-nc-nd Annals of Saudi Medicine 2017-01-01

Background: In India, the Home Based Postnatal Newborn Care programme by Accredited Social Health Activists (ASHAs) under National Rural Mission was initiated in 2011 to reduce neonatal mortality rates (NMRs).ASHAs get cash incentives for six postnatal home visits newborn care.We studied care practices among mothers Mewat, Haryana, having a high NMR and determined risk factors unsafe described knowledge skills of ASHAs during visits.Methods: A cross-sectional survey conducted who had...

10.5365/wpsar.2014.5.1.006 article EN cc-by Western Pacific surveillance response journal 2014-08-11

The global prevalence of obesity has surged to epidemic proportions, posing a significant threat public health in the twenty-first century. Beyond its established association with metabolic diseases, profoundly impacts cardiovascular health, serving as major risk factor for various illnesses (CVDs), including coronary artery disease, heart failure, hypertension, and stroke. Mechanistically, triggers cascade pathophysiological processes, chronic inflammation insulin resistance, exacerbating...

10.2174/0118715303317750250210055338 article EN Endocrine Metabolic & Immune Disorders - Drug Targets 2025-03-19

Abstract Polycystic ovary syndrome (PCOS) is most common in women of reproductive age, giving rise to androgen excess and anovulation, leading infertility non‐reproductive complications. We explored the ameliorating effect naringenin PCOS using Sprague Dawley (SD) rat model human granulosa cells. Letrozole‐induced rats were given either (50 mg/kg/day) alone or combination with metformin (300 mg/kg/day), followed by estrous cycle, hormonal analysis, glucose sensitivity test. To evaluate on...

10.1002/ptr.7860 article EN Phytotherapy Research 2023-05-10

BACKGROUND: Amidst corona virus disease-2019 (COVID-19) pandemic, disruption to the usual ways of life can lead anxiety and feeling being unsafe, which may be associated with self-medication. The study was planned investigate prevalence self-medication during COVID-19 pandemic. MATERIALS AND METHODS: In this cross-sectional study, data were collected through an anonymous online survey questionnaire consisting four sections: demographic participants, validated Anxiety Inventory Items,...

10.4103/jehp.jehp_864_20 article EN cc-by-nc-sa Journal of Education and Health Promotion 2021-01-01

Gastrointestinal (GI) cancers account for one-fourth of the global cancer incidence and are incriminated to cause one-third cancer-related deaths. GI includes esophageal, gastric, liver, pancreatic, colorectal cancers, mostly diagnosed at advanced stages due a lack accurate markers early stages. The invasiveness diagnostic methods like colonoscopy solid biopsy reduces patient compliance as it cannot be frequently used screen patients. Therefore, minimally invasive approaches liquid may...

10.3389/fmolb.2024.1385238 article EN cc-by Frontiers in Molecular Biosciences 2024-05-06

Abstract The rapid emergence of coronavirus disease 2019 (COVID-19) as a global pandemic affecting millions individuals globally has necessitated sensitive and high-throughput approaches for the diagnosis, surveillance determining genetic epidemiology SARS-CoV-2. In present study, we used COVIDSeq protocol, which involves multiplex-PCR, barcoding sequencing samples detection deciphering We approach on 752 clinical in duplicates, amounting to total 1536 could be sequenced single S4 flow cell...

10.1101/2020.08.10.242677 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-08-10

Tuberculosis of the adrenal glands is a common cause Addison's disease in developing countries. We conducted study to determine if treatment such patients with modern anti-tuberculous chemotherapy would lead an improvement plasma cortisol and aldosterone levels.Prospective study.5 secondary tuberculosis.Basal ACTH stimulated levels were measured prior instituting chemotherapy, as well one month after its conclusion. Four again studied over next 2-5 years.Peak markedly reduced (range, <...

10.1046/j.1365-2265.1998.00409.x article EN Clinical Endocrinology 1998-03-01

Diffusion tensor imaging (DTI) has been used to study the structure of ordered biological tissue. DTI-derived metrics correlate with inflammatory cytokines and adhesion molecules, expressed in brain abscess. We aimed role delineating synovitis their correlation proteins SF chronic arthritis patients.DTI was performed on 18 patients 6 healthy controls. A follow-up DTI at months 10 patients. Quantification (TNF-alpha, IL-1beta) soluble intercellular molecule-1 (sICAM-1) performed.DTI-derived...

10.1093/rheumatology/ken499 article EN Lara D. Veeken 2009-01-28

Descemet membrane detachment (DMD) is a significant complication noted during or early after cataract surgery. Review of literature revealed few cases delayed-onset DMD with presentation ranging from weeks to months surgery but most them were treated pneumatic descemetopexy and ended in penetrating keratoplasty. We report this case, highlight the usefulness corneal venting incision air tamponade late-onset not responding descemetopexy. A retrospective case review 66 year old male who...

10.1186/s12886-016-0212-6 article EN cc-by BMC Ophthalmology 2016-04-04

Despite having the highest number of preterm births globally, no genomic study on birth was previously published from India or other South-Asian countries.We conducted a genome-wide association (GWA) spontaneous (sPTB) 6211 women India. We used novel resampling procedure to identify associated single nucleotide polymorphisms (SNPs) followed by haplotype analysis and imputation.We found that 512 maternal SNPs were with sPTB (p < 2.51e-3), which minor allele at 19 (after Bonferroni correction)...

10.1016/j.lansea.2023.100190 article EN cc-by-nc-nd The Lancet Regional Health - Southeast Asia 2023-04-18

Fractional exhaled nitric oxide (FeNO) is a convenient to use biomarker of airway inflammation. However, the mutual relationship between FeNO, peripheral blood eosinophil, total immunoglobulin E (IgE) and inflammatory cytokines showed some controversy.This study was carried out determine accuracy eosinophil IgE detect eosinophilic inflammation as determined by two FeNO cutoff points. The correlation certain also examined.Seventy-six patients with partly controlled asthma performed following...

10.2147/jaa.s274022 article EN cc-by-nc Journal of Asthma and Allergy 2020-10-01

The effect of various antihypertensive medications on platelet function is increasing interest. Conflicting effects captopril are reported and the impact angiotensin converting enzyme (ACE) inhibitors not containing a sulfhydryl group such as enalapril, lisinopril, quinapril remains unstudied. Therefore, aim present study was to examine treatment with quinapril, novel ACE inhibitor group, function. Ten white men (age range 32–61 years) untreated mild-to-moderate essential hypertension...

10.1097/00005344-199101000-00003 article EN Journal of Cardiovascular Pharmacology 1991-01-01
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