A5021260853- Clinical Laboratory Practices and Quality Control
- Meta-analysis and systematic reviews
- Statistical Methods in Clinical Trials
- Hemodynamic Monitoring and Therapy
- Healthcare cost, quality, practices
- Health and Medical Research Impacts
- Quality and Safety in Healthcare
- Reliability and Agreement in Measurement
- Atrial Fibrillation Management and Outcomes
- Bacterial Identification and Susceptibility Testing
- Scientific Measurement and Uncertainty Evaluation
- Advanced Statistical Process Monitoring
- Ethics in Clinical Research
- Biomedical and Engineering Education
- Health Systems, Economic Evaluations, Quality of Life
- Health Sciences Research and Education
- Clinical practice guidelines implementation
- Cardiac Arrhythmias and Treatments
- Renal function and acid-base balance
- Clinical Reasoning and Diagnostic Skills
- AI in cancer detection
- Venous Thromboembolism Diagnosis and Management
- Radiology practices and education
- Cancer Genomics and Diagnostics
- Climate Change and Health Impacts
Royal College of Pathologists of Australasia
2016-2025
Australian National University
2015-2025
Bond University
2012-2023
Macquarie University
2018-2022
Azienda Ospedaliera di Padova
2022
University of Padua
2022
Walter de Gruyter (Germany)
2022
Australian Institute of Health and Welfare
2021
Fiona Stanley Hospital
2018
Sullivan Nicolaides Pathology
2003-2017
Objective Despite the growing number of point-of-care (POC) tests available, little research has assessed primary care clinician need for such tests. We therefore aimed to determine which POC they actually use or would like (if not currently available in their practice). Design Cross-sectional survey. Setting Primary Australia, Belgium (Flanders region only), Netherlands, UK and USA. Participants doctors (general practitioners, family physicians). Main measures asked respondents (1) identify...
The Australian government introduced temporary government-subsidised telehealth service items (phone and video-conference) in mid-March 2020 response to the COVID-19 pandemic. uptake of by patients with type 2 diabetes (T2DM) for consulting GPs is unknown.To evaluate consultations associated patient characteristics general practice, including frequency haemoglobin A1c (HbA1c) tests change HbA1c levels use, compared guideline recommendations.This exploratory study used electronic data from...
Abstract Background Machine learning (ML) has been applied to an increasing number of predictive problems in laboratory medicine, and published work date suggests that it tremendous potential for clinical applications. However, a groups have noted the pitfalls associated with this work, particularly if certain details development validation pipelines are not carefully controlled. Methods To address these other specific challenges when applying machine medicine setting, working group...
The Sigma metric is widely used in laboratory medicine.
The prevalence of heterophilic antibody interference in a modern immunochemiluminometric assay containing blocking agents was determined using thyrotropin as an illustrative example. Serum samples were obtained from 295 consecutive patients who underwent routine thyroid function testing. following versions the used: protocol A (zero blocker), B (routine blocker concentration), and C (extra blocker). Ten (prevalence 3.4%) had significant levels antibodies (protocol value greater than 9 SD...
The provision of interpretative advice on laboratory results is a post-analytic activity and an integral part clinical services. It valued by healthcare workers has the potential to prevent or reduce errors improve patient outcomes. important ensure that comments provided personnel are high quality: should be patient-focused answer implicit explicit question raised requesting clinician. Comment providers need adequately trained qualified able demonstrate their proficiency provide reports....
Abstract Background Patient-based real-time quality control (PBRTQC) avoids limitations of traditional methods based on the measurement stabilized samples. However, PBRTQC needs to be adapted individual laboratories with parameters such as algorithm, truncation, block size, and limit. Methods In a computer simulation, biases were added real patient results 10 analytes diverse properties. Different assessed their ability detect these early. Results The simulation 460 000 historical...
Abstract Background The harmonization status of most tumor markers (TMs) is unknown. We report a feasibility study performed to determine whether external quality assessment (EQA) programs can be used obtain insights into the current α-fetoprotein (AFP), prostate specific antigen (PSA), carcinoembryonic (CEA), cancer (CA)125, CA15-3 and CA19-9. Methods EQA sample results provided by 6 providers (INSTAND [Germany], Korean Association External Quality Assessment Service [KEQAS, South Korea],...
Abstract Objectives Recent advances in information technology have renewed interest patient-based real-time quality control (PBRTQC) as an alternative to internal (IQC). However, since regulations mandate IQC, PBRTQC can only be implemented a separate system. The additional labor required for may hinder widespread adoption. Therefore, more efficient system that integrates IQC with is needed laboratories implement the methods effectively. Methods A QC proposed. maximum average number of...