A5101405006- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Data Mining Algorithms and Applications
- Rough Sets and Fuzzy Logic
- Liver Disease Diagnosis and Treatment
- Microwave Imaging and Scattering Analysis
- Advanced SAR Imaging Techniques
- Asthma and respiratory diseases
- Liver Disease and Transplantation
- Data Management and Algorithms
- Hepatitis C virus research
- Non-Invasive Vital Sign Monitoring
- Nanoplatforms for cancer theranostics
- Endometriosis Research and Treatment
- GaN-based semiconductor devices and materials
- Radio Frequency Integrated Circuit Design
- Uterine Myomas and Treatments
- Radar Systems and Signal Processing
- Hepatitis B Virus Studies
- Cancer-related molecular mechanisms research
- Advanced Database Systems and Queries
- Cervical Cancer and HPV Research
- ECG Monitoring and Analysis
- Hemodynamic Monitoring and Therapy
- Microtubule and mitosis dynamics
Osaka Metropolitan University
2022-2024
Center for Clinical Research (United States)
2024
Ono Pharmaceutical (United Kingdom)
2024
Tokyo Metropolitan University
2022-2024
Osaka City University
2014-2023
ShinEtsu Chemical (Japan)
2022-2023
The Jikei University Hospital
2022
Gordon Center for Medical Imaging
2020-2022
Massachusetts General Hospital
2020-2022
Harvard University
2020-2022
We discuss data mining based on association rules for two numeric attributes and one Boolean attribute. For example, in a database of bank customers, "Age" "Balance" are attributes, "CardLoan" is Taking the pair (Age, Balance) as point two-dimensional space, we consider an rule form((Age, ∈ P) ⇒ (CardLoan = Yes),which implies that customers whose ages balances fall planar region P tend to use card loan with high probability. classes regions, rectangles admissible (i.e. connected x-monotone)...
Article Free Access Share on Mining optimized association rules for numeric attributes Authors: Takeshi Fukuda IBM Tokyo Research Laboratory, 1623-14, Shimo-tsuruma, Yamato City, Kanagawa Pref, 242, Japan JapanView Profile , Yasuhido Morimoto Shinichi Morishita Tokuyama Authors Info & Claims PODS '96: Proceedings of the fifteenth ACM SIGACT-SIGMOD-SIGART symposium Principles database systemsJune 1996Pages 182–191https://doi.org/10.1145/237661.237708Published:03 June 1996Publication History...
The objectives of this paper are to propose a method that can accurately estimate the human heart rate (HR) using an ultrawideband (UWB) radar system, and determine performance proposed through measurements. uses feature points signal HR efficiently accurately. Fourier- periodicity-based methods inappropriate for estimation instantaneous HRs in real time because heartbeat waveforms highly variable, even within beat-to-beat interval. We define six waveform features enable correlation...
The strategy of structure-inherent tumor targeting (SITT) with cyanine-based fluorophores is receiving more attention because no chemical conjugation moieties required. However, the mechanism behind SITT has not yet been well explained. Here, it demonstrated that heptamethine-cyanine-based possess only targetability microenvironments without need for additional ligands but also second near-infrared spectral window (NIR-II) imaging capabilities, i.e., minimum scattering and ultralow...
Abstract Near‐infrared (NIR) fluorescence imaging has advanced medical and image‐guided interventions during the past three decades. Despite tremendous advances in devices, surprisingly only a few dyes are currently available clinic. Previous fluorophores, ZW800‐1A ZW800‐1C, significantly improved poor performance of FDA‐approved indocyanine green. However, is not stable serum ZW800‐1C induces severe stacking aqueous media. To solve such dilemmas, ZW800‐PEG was designed by introducing...
Abstract Background and Aim: Terlipressin has been shown to be effective in the management of hepatorenal syndrome. However, how terlipressin exerts its effect on renal artery is unknown. The aim present study was assess effects systemic, hepatic hemodynamics cirrhosis. Methods: Twenty‐eight patients with cirrhosis portal hypertension were studied. Systemic hemodynamics, arterial resistive indices neurohumoral factors measured prior 30 min after intravenous administration 1 mg ( n = 19) or...
We discuss data mining based on association rules for two numeric attributes and one Boolean attribute. For example, in a database of bank customers, Age Balance are attributes, CardLoan is Taking the pair (Age, Balance) as point two-dimensional space, we consider an rule form ((Age,Balance) ∈P)⇒(CardLoan = Yes), which implies that customers whose ages balances fall within planar region P tend to take out credit card loans with high probability.We classes regions, rectangles admissible...
We discuss data mining based on association rules for two numeric attributes and one Boolean attribute. For example, in a database of bank customers, "Age" "Balance" are attributes, "CardLoan" is Taking the pair (Age, Balance) as point two-dimensional space, we consider an rule form(( Age, Balance ) ∈ P ⇒ ( CardLoan = Yes ),which implies that customers whose ages balances fall planar region tend to use card loan with high probability. classes regions, rectangles admissible...
Chemotherapy-induced neutropenia is a common complication in cancer treatment. In this study, we investigated chemotherapy-induced that was recently detected all patients with gynecologic malignancy. Between January 2009 and December 2011, examined cases of reported our hospital. We analyzed the incidence clinical features febrile During study period, administered over 1614 infusions (29 regimens) to 291 patients. The median age 60 years (range 24-84 years). occurred 147 (50.5%) 378 (23.4%)...
The residual tumor after surgery is the most significant prognostic factor of patients with epithelial ovarian cancer. Near-infrared (NIR) fluorescence-guided actively utilized for localization and complete resection during surgery. However, currently available contrast-enhancing agents display low on-target binding, unfavorable pharmacokinetics, toxicity, thus not ideal clinical use. Here we report ultrabright stable squaraine fluorophores optimal pharmacokinetics by introducing an...
Abstract Fluorescence‐guided surgery (FGS) aids surgeons with real‐time visualization of small cancer foci and borders, which improves surgical prognostic efficacy cancer. Despite the steady advances in imaging devices, there is a scarcity fluorophores available to achieve optimal FGS. Here, 1) pH‐sensitive near‐infrared fluorophore that exhibits rapid signal changes acidic tumor microenvironments (TME) caused by attenuation intramolecular quenching, 2) inherent targeting for based on...
The effects of transcervical microwave myolysis at 2.45 GHz after endometrial ablation for menorrhagia were examined in patients with myomas.A irradiation system assisted by transvaginal ultrasonic guidance was developed. Ten waiting caused myomas entered the study complete informed consent obtained. Their outcomes least 6 months using system. After completion ablation, interstitial performed a guiding needle set puncture adaptor attached to probe and applicator 1.6 mm diameter. Shrinkage...
We demonstrate an accurate remote measurement of heartbeats using ultra-wideband radar system. Although most conventional systems use either continuous waves or impulse-radio for vital monitoring, suffer from non-stationary clutters, while cannot detect heartbeats. Our system has a moderate fractional bandwidth intermediate these systems, resulting in both the suppression clutters and high sensitivity measuring heart rates even dynamic environment. A simultaneous signal participant employing...
Vital-sign estimation using ultra-wideband (UWB) radar is preferable because it contactless and less privacy-invasive. Recently, many approaches have been proposed for estimating heart rate from UWB data. However, their performance still not reliable enough practical applications. To improve the accuracy, this study employs convolutional neural networks to learn special patterns of heartbeats. In system, skin displacements target person are measured radar, signal converted a two-dimensional...
Outstanding GaN-based HFETs (HFET: Heterojunction Field-Effect Transistors) [1] power devices are expected to replace all Si in high applications such as inverter systems due their excellent performance. In order exploit the full potential of emerging GaN devices, gate driver that controls device by a pulse width modulation (PWM) signal is becoming more important. The vital function provide an isolated against reference source voltage operates at voltage. addition this function, integration...
To improve our understanding of cervical adenocarcinoma (AD) and evaluate the clinical pathological variables affecting its prognosis, we retrospectively reviewed medical records 455 patients with cancer [International Federation Gynecology Obstetrics stage I/II; 91 cases AD 364 squamous cell carcinoma (SCC)] who underwent surgery at hospital between January, 1995 August, 2012 compared characteristics prognoses SCC cases, including age, stage, histological type, lymph node metastasis,...
Enormous efforts have been made to integrate various therapeutic interventions into multifunctional nanoplatforms, resulting in the advance of nanomedicine. Image-guided drug delivery plays a pivotal role this field by providing specific targeting as well image navigation for disease prognosis.
Alkoxysilanes are important precursors of silicone materials for which various synthesis methods have been reported. However, these approaches not without problems, and hence, halogen-free, HF-free, room-temperature reactions producing alkoxysilanes required. In this study, we demonstrated a direct low-temperature (∼40 °C) alkoxysilane method that did involve halogens or HF. Si, Cu, ethanol were milled in planetary ball mill 2 h, 50% yield tetraethoxysilane (TEOS) was obtained; addition,...
Although the anti-hepatitis C virus (HCV) effect of statins in vitro and clinical efficacy fluvastatin combined with Pegylated interferon (PEG-IFN)/ribavirin therapy for chronic hepatitis (CHC) have been reported, details presentation are largely unknown. We focused on viral relapse that influences treatment outcome, performed a post-hoc analysis by using data from randomized controlled trial.Thirty-four patients group 33 non-fluvastatin who achieved virological response (complete early...
Measurement of heartbeats is essential in cardiovascular magnetic resonance imaging because the measurement must be synchronized with phase cardiac cycles. Many existing studies on radar-based heartbeat monitoring have focused echoes from torso only, and such cannot applied to subjects scanners only head soles can seen outside. In this study, we demonstrate feasibility remote subject’s using a 60-GHz ultra-wideband radar. The intervals measured radar are quantitatively compared those...