A5040866854- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Congenital Heart Disease Studies
- ECG Monitoring and Analysis
- Radiation Dose and Imaging
- Medical Image Segmentation Techniques
- Wireless Body Area Networks
- Venous Thromboembolism Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Neuroscience and Neural Engineering
- Genetic Associations and Epidemiology
- Electromagnetic Fields and Biological Effects
- Cardiomyopathy and Myosin Studies
- Infective Endocarditis Diagnosis and Management
- Atomic and Subatomic Physics Research
- Medical Imaging Techniques and Applications
- Health Systems, Economic Evaluations, Quality of Life
- Coronary Interventions and Diagnostics
- Lipoproteins and Cardiovascular Health
Deutsches Herzzentrum München
2016-2025
München Klinik
2014-2025
Technical University of Munich
2015-2024
Deutsches Herzzentrum der Charité
2017-2023
German Centre for Cardiovascular Research
2020-2023
Hôpital Cardiologique du Haut-Lévêque
2018-2022
Electrophysiology and Heart Modeling Institute
2018-2022
Université de Bordeaux
2018-2022
Centre Hospitalier Universitaire de Bordeaux
2018-2022
Inserm
2019-2020
Abstract Introduction Radiofrequency (RF) lesion metrics are influenced by underlying parameters like RF power, duration, and contact force (CF), utilization of metric indices (ablation index [AI]) is a proposed strategy to predict quality. The aim this study was analyze the influence on high‐power short‐duration (HPSD) standard applications using an in silico ex vivo model. Methods Results An simulation designed simulate HPSD ablations, which ablation could systematically be varied. For...
Pulmonary vein isolation (PVI) using radiofrequency ablation (RFA) in patients with paroxysmal atrial fibrillation (PAF) is effective but hampered by pulmonary reconnection due to insufficient lesions. High-power delivery over a short period of time (HPSD) RFA stated create more efficient The aim this study was compare intraprocedural safety and outcome HPSD conventional power settings undergoing PVI for PAF.We included 197 PAF that were scheduled PVI. An protocol 70 W duration cut-off 7 s...
Despite advanced ablation strategies and major technological improvements, treatment of persistent atrial fibrillation (AF) remains challenging the underlying pathophysiology is not fully understood. This study analyzed multiple procedure outcome safety catheter spatiotemporal dispersions (DISPERS) detected by artificial intelligence (AI)-guided software in patients with long-standing AF.
Despite substantial progress in recent years, graft survival beyond the first year still requires improvement. Since modern immunosuppression addresses mainly T-cell activation and proliferation, we studied macrophage infiltration into allografts of 103 kidney transplant recipients during acute antibody mediated rejection. Macrophage was correlated with both function until month 36 after transplantation.Macrophage significantly elevated antibody-mediated rejection, but not kidneys...
Abstract Introduction Successful catheter ablation is limited by both poor spatial resolution of abnormal local signals and inability to deliver an effective lesion due tissue contact. We report first worldwide use the Intellanav MiFi OI (Boston Scientific), providing ultra‐high density mapping incorporating a “DirectSense” algorithm measure impedance (LI). Methods results 31 patients (65±6 years, 20 male) underwent ablation. LI from catheter, generator (GI) maximum electrogram amplitude...
Abstract Background Pulse field ablation (PFA) is a novel catheter technology with potential safety benefits due to its tissue selectivity. It has the directly damage or interact functionality of cardiac implantable electronic devices (CIEDs) in form electromagnetic interference (EMI). The aim our study was assess impact PFA on CIEDs. Methods lesions (45 per CIED) were applied from Farapulse system CIEDs (< 5 cm lead tip and < 15 generator). All checked before after application for...
Background: Atrial fibrillation ablation–related atrial tachycardia (AT) is complex and may demonstrate several forms: anatomic macroreentrant AT (AMAT), non-AMAT, focal AT. We aimed to elucidate the recurrence rate mechanisms of recurrence. Methods: Among 147 patients with ATs treated Rhythmia system, 68 (46.3%) had at mean 4.2 (2.9–11.6) months, 44 received a redo procedure. circuits in first procedure were compared those Results: Although mappable not observed 7 patients, 37 during...
We hypothesized that an epicardial approach using ethanol infusion in the vein of Marshall (EIVOM) may improve result ablation for perimitral flutter (PMF).We studied 103 consecutive patients with PMF undergoing high-resolution mapping. The first 71 were treated radiofrequency (RF) alone (RF-group), and next 32 underwent EIVOM followed by RF on endocardial mitral isthmus (EIVOM/RF-group). Contact force was not measured during ablation. Acute 1-year outcomes compared. Flutter termination...
Pulmonary vein isolation (PVI) using radiofrequency ablation (RFA) is an established treatment strategy for atrial fibrillation (AF). To improve PVI efficacy and safety, high-power short-duration (HPSD) pulsed-field (PFA) were recently introduced into clinical practice. This study aimed to determine the extent of myocardial injury systemic inflammation following PFA, HPSD, standard RFA biomarkers.
ABSTRACT Introduction Data regarding safety and long‐term outcome of very high‐power‐short duration (vHPSD) ablation in adult congenital heart disease (ACHD) patients with paroxysmal or persistent atrial fibrillation (AF) are lacking. Methods Retrospective observational single‐center study. The data 66 consecutive ACHD (mean age 60 ± 12.8 years, 46% male) mild (69.7%), moderate (22.7%), complex (7.6%) (CHD) who underwent for (40.9%) AF (59.1%) were analyzed. Circumferential PVI was performed...
Accuracy of Catheter Guidance Technology in the EP Lab Background With increasing complexity electrophysiology (EP) procedures, use electroanatomic mapping systems (EAMS) as a supplement to fluoroscopy has become common practice. This is first study that evaluates spatial and point localization accuracy for 2 current EAMS, CARTO3 ® (Biosense Webster, Diamond Bar, CA, USA) EnSite Velocity (St. Jude Medical Inc., St. Paul, MN, USA), novel overlay guidance (OG) software (Siemens AG, Forchheim,...
Contact-force (CF) sensing catheters are increasingly used in electrophysiological procedures due to their efficacy and safety profile. As data about the accuracy of fiberoptic CF technology scarce, we sought quantify it using vitro experiments.A force sensor was built with a flexible membrane allow exact reference measurements for each set experiments. A TactiCath Quartz (TCQ) ablation catheter brought contact order compare TCQ measurements. Measurements were performed at different tip...