A5066861915- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- ECG Monitoring and Analysis
- Ion channel regulation and function
- Cardiovascular Effects of Exercise
- Cardiovascular Syncope and Autonomic Disorders
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Cardiomyopathy and Myosin Studies
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Advanced MRI Techniques and Applications
- Microbial Inactivation Methods
- Ultrasound in Clinical Applications
- Sexual Differentiation and Disorders
- Hydrogen embrittlement and corrosion behaviors in metals
- Contact Dermatitis and Allergies
- Receptor Mechanisms and Signaling
- Healthcare Systems and Practices
- Cardiovascular Function and Risk Factors
- Chronic Disease Management Strategies
Université de Bordeaux
2017-2024
Electrophysiology and Heart Modeling Institute
2016-2024
Hôpital Cardiologique du Haut-Lévêque
2017-2023
Centre Hospitalier Universitaire de Bordeaux
2017-2023
Inserm
2016-2023
Centre de Recherche Cardio-Thoracique de Bordeaux
2019-2023
Lille’s Cardiology Hospital
2022
Bordeaux Population Health
2020-2021
Hôpital Sahloul
2018-2019
University of Sousse
2018
Abstract Introduction Radiofrequency (RF) lesion metrics are influenced by underlying parameters like RF power, duration, and contact force (CF), utilization of metric indices (ablation index [AI]) is a proposed strategy to predict quality. The aim this study was analyze the influence on high‐power short‐duration (HPSD) standard applications using an in silico ex vivo model. Methods Results An simulation designed simulate HPSD ablations, which ablation could systematically be varied. For...
Extra-atrial injury can cause complications after catheter ablation for atrial fibrillation (AF). Pulsed field (PFA) has generated preclinical data suggesting that it selectively targets the myocardium. We sought to characterize extra-atrial injuries pulmonary vein isolation (PVI) between PFA and thermal methods.Cardiac magnetic resonance (CMR) imaging was performed before, acutely (<3 h) 3 months post-ablation in 41 paroxysmal AF patients undergoing PVI with (N = 18, Farapulse) or methods...
We conducted a multicenter study to evaluate mapping and ablation of ventricular fibrillation (VF) substrates or VF triggers in early repolarization syndromes (ERS) J-wave syndrome (JWS).We studied 52 patients with ERS (4 women; median age, 35 years) recurrent episodes. Body surface electrocardiographic imaging endocardial epicardial electroanatomical both ventricles were performed during sinus rhythm for localization triggers, substrates, drivers. Ablations on defined as areas that had late...
Background: Sudden cardiac death because of ventricular fibrillation (VF) is commonly unexplained in younger victims. Detailed electrophysiological mapping such patients has not been reported. Methods: We evaluated 24 (29±13 years) who survived idiopathic VF. First, we used multielectrode body surface recordings to identify the drivers maintaining Then, analyzed electrograms driver regions using endocardial and epicardial catheter during sinus rhythm. Established electrogram criteria were...
Ventricular tachycardia (VT) with structural heart disease is dependent on reentry within scar regions. We set out to assess the VT circuit in greater detail than has hitherto been possible, using ultra-high-density mapping.All mapping guided ablation cases from 6 high-volume European centers were assessed. Maps analyzed offline generate activation maps of circuits. Topography, conduction velocity, and voltage complete maps.Thirty-six tachycardias 31 patients identified, 29 male 27 ischemic....
Pulsed field ablation (PFA), a non-thermal ablative modality, may show different effects on the myocardial tissue compared to thermal ablation. Thus, this study aimed compare left atrial (LA) structural and mechanical characteristics after PFA vs. ablation.Cardiac magnetic resonance was performed pre-ablation, acutely (<3 h), 3 months post-ablation in 41 patients with paroxysmal fibrillation (AF) undergoing pulmonary vein (PV) isolation (n = 18) or 23, 16 radiofrequency ablations, 7...
Achieving bidirectional mitral isthmus (MI) block using radiofrequency catheter ablation (RFCA) alone is challenging, and MI reconnection common. Adjunctive vein of Marshall (VOM) ethanol infusion (VOM-Et) can facilitate acute block. However, little known about its long-term success. This study sought to evaluate the impact adjunctive VOM-Et on achievement durability compared with RFCA alone.Patients undergoing first attempt posterior were grouped according their index strategy: alone. Rates...
Background: Vein of Marshall (VOM) ethanol infusion is a relatively new therapeutic option for atrial tachyarrhythmias. We aimed to evaluate the feasibility, pitfalls, and complications associated with this procedure in large cohort patients. Methods: Successful infusion, VOM-related lesion extent, serious were evaluated 713 consecutive patients treated VOM infusion. Results: While feasible 88.9% cases, failure mainly resulted from nonidentification (6.2%), noncannulation (1.5%), or wrong...
Mapping data of human ventricular fibrillation (VF) are limited. We performed detailed mapping the activities underlying onset VF and targeted ablation in patients with structural cardiac abnormalities.
Background: Biatrial tachycardia (BiAT) is a rare form of atrial macroreentrant tachycardia, in which both atria critical part the circuit. We aimed to identify characteristics and precise circuits single-loop BiATs. Methods Results: identified 8 patients (median age, 59.5 years old) with 9 BiATs cohort 336 consecutive from 2 institutions who had undergone AT catheter ablation using an automatic ultrahigh-resolution mapping system. Seven history persistent AF ablation, including septal or...
Background: Long-term results of substrate modification for ablation ventricular tachycardia (VT) have not been reported. We report long-term outcomes elimination targeting local abnormal activities (LAVA) post–myocardial infarction VT. Methods and Results: One hundred fifty-nine consecutive patients undergoing first were included (65±11 years, 92% implantable cardioverter defibrillators, 54% storms, 73% appropriate shocks). LAVA identified in VT was inducible 73%. Complete noninducibility...
Abstract Introduction Successful catheter ablation is limited by both poor spatial resolution of abnormal local signals and inability to deliver an effective lesion due tissue contact. We report first worldwide use the Intellanav MiFi OI (Boston Scientific), providing ultra‐high density mapping incorporating a “DirectSense” algorithm measure impedance (LI). Methods results 31 patients (65±6 years, 20 male) underwent ablation. LI from catheter, generator (GI) maximum electrogram amplitude...
Background: Atrial fibrillation ablation–related atrial tachycardia (AT) is complex and may demonstrate several forms: anatomic macroreentrant AT (AMAT), non-AMAT, focal AT. We aimed to elucidate the recurrence rate mechanisms of recurrence. Methods: Among 147 patients with ATs treated Rhythmia system, 68 (46.3%) had at mean 4.2 (2.9–11.6) months, 44 received a redo procedure. circuits in first procedure were compared those Results: Although mappable not observed 7 patients, 37 during...
We hypothesized that an epicardial approach using ethanol infusion in the vein of Marshall (EIVOM) may improve result ablation for perimitral flutter (PMF).We studied 103 consecutive patients with PMF undergoing high-resolution mapping. The first 71 were treated radiofrequency (RF) alone (RF-group), and next 32 underwent EIVOM followed by RF on endocardial mitral isthmus (EIVOM/RF-group). Contact force was not measured during ablation. Acute 1-year outcomes compared. Flutter termination...