A5053582363- Effects and risks of endocrine disrupting chemicals
- Microplastics and Plastic Pollution
- Carcinogens and Genotoxicity Assessment
- Biosimilars and Bioanalytical Methods
- Indoor Air Quality and Microbial Exposure
- Air Quality and Health Impacts
- Antibiotics Pharmacokinetics and Efficacy
- Chemistry and Chemical Engineering
- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Tryptophan and brain disorders
- Biosensors and Analytical Detection
- Forensic Toxicology and Drug Analysis
- Pesticide Exposure and Toxicity
- Hormonal and reproductive studies
- Pharmacological Effects and Toxicity Studies
- Toxic Organic Pollutants Impact
- Metabolomics and Mass Spectrometry Studies
- Pesticide Residue Analysis and Safety
- Environmental Toxicology and Ecotoxicology
- Advanced Biosensing Techniques and Applications
- Occupational exposure and asthma
- Pharmacological Effects and Assays
- SARS-CoV-2 detection and testing
- Viral gastroenteritis research and epidemiology
Universidade Feevale
2014-2025
Abstract Bisphenol A (BPA) is an emerging contaminant, regularly detected in aquatic ecosystems, considered as endocrine disrupting compound (EDC). Caffeine another chemical related to human activity, often found surface waters. The objective of this study was evaluate the ecotoxicological risk due BPA and caffeine water samples from Sinos River basin, Rio Grande do Sul, Brazil. Water were collected at three sites monthly May 9 th, 2016 April 11th, 2017 (n = 36). concentrations range not 517...
A LC-MSMS method for the simultaneous determination of tamoxifen, N-desmethyltamoxifen, 4-hydroxytamoxifen and endoxifen in dried blood spots samples was developed validated. The employs an ultrasound-assisted liquid extraction a reversed phase separation Acquity(®) C18 column (150×2.1 mm, 1.7 µm). Mobile mixture formic acid 0.1% (v/v) pH 2.7 acetonitrile (gradient from 60:40 to 50:50, v/v). Total analytical run time 8 min. Precision assays showed CV % lower than 10.75% accuracy range 94.5...
Parabens (PBs) and bisphenols are endocrine disruptors (EDs) widely used in everyday products associated with health issues, such as reproductive disorders, breast cancer, obesity, hypertension, asthma. Hair has been proposed an alternative matrix due to its ability reflect prolonged exposure while being less affected by short-term fluctuations. This study developed a rapid sensitive analytical method for the determination of PBs (butylparaben, methylparaben, ethylparaben, propylparaben)...
The evaluation of formaldehyde (FD) exposure in beauty salons, due to the use hair straightening products, and its relation with genotoxicity biomarkers was performed this study. Regardless official recommendations, inappropriate homemade creams has became a popular practice Brazil, high content "progressive straightening" can contain mutagens that could increase incidence neoplasia those people who them. Damage DNA assessed by conducting micronuclei test (MNT) on buccal cells comet assay...
Formaldehyde (FA) is a chemical widely used in the furniture industry and has been classified as potential human carcinogen. The purpose of this study was to evaluate occupational exposure workers FA at manufacturing facility relationship between environmental concentrations FA, formic acid concentration urine, DNA damage. sample consisted 46 exposed control group 45 individuals with no history exposure. Environmental were determined by high-performance liquid chromatography. Urinary gas...
Identifying drugs of abuse and their metabolites in plasma is vital both forensic clinical toxicology. While the QuEChERS (Quick, Easy, Cheap, Effective, Rugged Safe) method offers an efficient approach to sample preparation, its application complex due wide-ranging properties target analytes challenges posed by biological matrix interferences. This study aims develop a microQuEChERS for quantification 14 utilizing minimal solvent volumes.
Bisphenol A (BPA), an endocrine disruptor present mostly in polycarbonate plastics and epoxy resins, can migrate into food beverages, resulting human exposure. This study aimed to develop validate improved liquid chromatography-tandem mass spectroscopy (LC-MS/MS) method for measuring BPA levels urine, applying this exposure evaluation a Brazilian cohort, along with hair levels. Samples from 100 volunteers were collected. Urine samples extracted using automated solid-phase extraction...