- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Liver Disease Diagnosis and Treatment
- Celiac Disease Research and Management
- Pharmacological Effects and Toxicity Studies
- Child Nutrition and Feeding Issues
- COVID-19 and healthcare impacts
- Pharmaceutical Practices and Patient Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Ultrasound in Clinical Applications
- Head and Neck Cancer Studies
- Colorectal Cancer Surgical Treatments
- Body Contouring and Surgery
- Diabetes Management and Education
- Lightning and Electromagnetic Phenomena
- Neurogenetic and Muscular Disorders Research
- Colorectal Cancer Treatments and Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Intraperitoneal and Appendiceal Malignancies
- Pregnancy and Medication Impact
Luton and Dunstable University Hospital NHS Foundation Trust
2025
University Hospital Southampton NHS Foundation Trust
2011-2024
Queensland University of Technology
2023
University Hospitals Birmingham NHS Foundation Trust
2018-2022
Royal Berkshire Hospital
2021
Royal Berkshire NHS Foundation Trust
2021
University of Birmingham
2020
Queen Elizabeth Hospital Birmingham
2020
Good Hope Hospital
2020
Heart of England NHS Foundation Trust
2019
Uterine carcinosarcoma (UCS) refers to a rare high-grade aggressive epithelial non-endometrioid endometrial carcinoma, with tumour cells demonstrating epithelial-mesenchymal metaplastic transition and composed of both carcinomatous sarcomatous (homologous or heterologous) components. The aim this study was evaluate the epidemiology, management approach, outcomes survival patterns patients UCS. Seventy-seven cases UCS treated primary surgery in single tertiary centre underwent retrospective...
Health-related concerns brought on by the COVID-19 pandemic and impact of specific local national interventions have not been explored in patients with inflammatory bowel disease (IBD) UK. We evaluated perspectives IBD effectiveness information dissemination addressing concerns.We prospectively conducted a survey among during to assess concerns, information-seeking behaviours, risk perception, compliance effect interventions.A total 228 were interviewed whom 89% reported being concerned...
Objective Percutaneous endoscopic gastrostomy (PEG) tube placement is associated with a high risk of cardiorespiratory complications in patients significant respiratory compromise. This study reports case series high-risk undergoing PEG using modified technique—nasal unsedated seated (nuPEG) placement. Design Retrospective review 67 at between September 2012 and December 2016. Setting UK specialist tertiary centre for clinical nutrition support. Interventions Patients underwent ‘push’ nasal...
Background and Aim Dye‐based chromoendoscopy ( DCE ) with targeted biopsies is recommended for inflammatory bowel disease IBD surveillance. However, has not yet been widely adopted into clinical practice. We evaluated quality indicators in surveillance following introduction of structured changes service delivery. Methods In August 2016, we introduced a number to practice our endoscopy unit. These included training using interactive videos/images module, as standard by foot‐pedal operated...
Aims Percutaneous endoscopic gastrostomy (PEG) is an established route for enteral nutrition. Although rare, buried bumper syndrome (BBS) remains important and challenging complication to manage. Gastric mucosal overgrowth over the internal results in obstruction of stoma impedes delivery nutritional feeds via PEG tube. Many different techniques treating BBS have been described, but these largely limited case reports or small series. This study aimed determine efficacy safety T-piece pull technique
Aims A rare complication following the removal of a percutaneous endoscopic gastrostomy (PEG) tube is formation gastocutaneous fistula (GF). Although number techniques have been described for managing GF, to date there very little data on efficacy over-the-scope clips in treating GF. In this study we aimed determine and safety clip treatment persistent
<h3>Introduction</h3> Intravenous sedation for colonoscopy is associated with cardiorespiratory risk and delayed recovery. There also the perception that patients tolerate procedure better sedation. Moreover some studies suggest performance compromised if do not well. This study aimed to compare inhaled nitrous oxide (entonox) intravenous during in terms of completions rates, patient comfort changes physiological status. <h3>Methods</h3> 288 undergoing elective were included performed by a...
There is mounting evidence to support the impact of sarcopenia on prognosis a wide range clinical conditions. This review examines literature effect body composition measures, including sarcopenia, outcomes in patients with hepatocellular carcinoma (HCC). Available studies adverse that has overall survival, response different treatment modalities, and tumour recurrence. Some have identified visceral fat deposition as negative prognostic sign, incorporation measures into current HCC staging...
Abstract Objective To explore community pharmacy consumers’ knowledge and attitudes of mental illness, support services, pharmacists’ role in supporting people living with illness (PLMI). Methods This survey was conducted 15 pharmacies between June September 2019. Participants were aged 18 years or older without prior ongoing history and/or close family members illness. Open-ended responses to the anonymous questionnaire analysed using content analysis. Key findings Majority 380 participants...
Prescription error rates and delays in treatment provision are high for N-acetylcysteine (NAC) when prescribed paracetamol overdose (POD). We hypothesised that an electronic tool which proposed the complete NAC regimen would reduce prescription errors improve timeliness of provision. Error were assessed following POD, before after implementation prescribing tool.The three infusions (dosed weight) entry patient's weight. All prescriptions reviewed during a three-month period prior to tool's...
Introduction: Vitamin D exerts a number of immunomodulatory effects. Studies have shown link between vitamin deficiency and incidence acute rejection infection in solid organ transplant recipients but none examined small bowel multivisceral transplantation. We hypothesised that following or may increase the risk rejection, cytomegalovirus (CMV) infection, sepsis post-transplant lymphoproliferative disorder (PTLD). Methods: This was single centre retrospective review patients who had received...
Abstract Polyglucosan inclusion body myopathy (PIBM) is a recently described gastrointestinal neuromuscular disease. Given its rarity, very little known of natural history and prognosis. In this case report, we present the first PIBM resultant intestinal failure in which, following 7 years home parenteral nutrition, symptoms subsided nutrition autonomy was restored.
Currently dye-based chromoendoscopy (DCE) is recommended for Inflammatory Bowel Disease (IBD) surveillance. However DCE has not been widely adopted into clinical practice yet. We aimed to evaluate performance in IBD surveillance colonoscopy following introduction of structured changes delivery service.
<h3>Introduction</h3> Patients on home parenteral nutrition (HPN) are recognised to be at high risk of metabolic bone disease (MBD). ESPEN guidelines recommend screening with annual DEXA (Dual-energy X-ray absorptiometry) scans for all patients HPN. The National Institute Health and Care Excellence states that should not routinely performed without prior assessment e.g. by Fracture Risk Assessment Tool (FRAX). FRAX is used pre-DEXA estimate the 10 year probability major osteoporotic or hip...