A5043470325- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Metastasis and carcinoma case studies
- Cancer Diagnosis and Treatment
- Geological and Geochemical Analysis
- Surgical site infection prevention
- Anesthesia and Neurotoxicity Research
- Geochemistry and Elemental Analysis
- Sepsis Diagnosis and Treatment
- Erythrocyte Function and Pathophysiology
- Social and Behavioral Studies
- Venous Thromboembolism Diagnosis and Management
- Renal cell carcinoma treatment
- Renal and Vascular Pathologies
- Cancer, Hypoxia, and Metabolism
- Photodynamic Therapy Research Studies
- Gastrointestinal Tumor Research and Treatment
- Microbial Metabolism and Applications
- Medical and Agricultural Research Studies
- Hemophilia Treatment and Research
- Scientific Research and Studies
- Geochemistry and Geologic Mapping
- Bladder and Urothelial Cancer Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Mycobacterium research and diagnosis
Geological Institute
2025
Ufa Institute of Chemistry
2024
Czech Academy of Sciences, Institute of Geology
2024
Rostov State Medical University
2023
Ministry of Health of the Russian Federation
2021
Rostov Research Institute of Oncology
2016-2020
A number of aspects using U-Pb isotope ages detrital zircon populations to decipher the composition and spatial location provenances are discussed. It is shown that when analyzing interpreting such data, it important remember chemical characteristics can be used identify clastic sources map their transport routes sinks only in cases where material was formed directly by erosion crystalline (igneous metamorphic) rocks / protosources. Recycling older sedimentary strata, which source a...
Aim. To study the levels of reduced and oxidized glutathione (GSH GSSG, respectively), as well thiol status in gastric cancer (GC) tumors various histological types grades. Materials methods. The indicators were determined by ELISA methods tumor, peritumoral visually intact tissues obtained during surgery from 52 patients with GC: 18 had a G1-2 adenocarcinoma (AC), 8 G3 AC, 6 signet ring cell (SRCC), 14 combined lesions (CGL) – AC fragments, component undifferentiated cancer, G4. Results. In...
The purpose is to evaluate the detoxification effects of polymyxin sorption columns and filtration using polymethyl methacrylate membranes in abdominal sepsis cancer patients. Materials Methods . We examined 226 patients with oncological diseases organs complicated by postsurgery. In 50 cases, septic shock was reported. 173 an acute renal injury (ARI) diagnosed structure organ failures, which a combination respiratory distress syndrome (ARDS) 61 severity 26.3±3.3 points (APACHE-II scale),...
Purpose of the study . Exploring erythrocyte glutathione system functioning in patients with gastric cancer a comparative aspect, depending on tumor histotype and disease prevalence. Patients methods The included 89 cancer, divided into 6 groups tumor. Separately, results were analyzed T4 status according to TNM at stage 4. content reduced activity glutathione-dependent enzymes erythrocytes patients' blood studied by conventional spectrophotometric methods. Statistical processing was carried...
To compare early results after pancreaticoduodenectomy depending on variant of pancreatico-digestive anastomosis.It was analyzed 207 pancreaticoduodenectomies for cancer which were performed the period 2010-2014. Pancreatointestinal and pancreatogastric anastomoses applied in 165 42 patients respectively.Complications observed 73 (44.2%) 18 (38.3%) pancreatointestinal respectively. Six died anastomosis. At same time there no deaths group Differences significant. Postoperative hospital-stay...
Using clay rocks of the Riphean stratotype (Bashkir meganticlinorium, Southern Urals) as an example, we compared results reconstructing composition provenances fine-grained aluminosiliciclastics obtained by dint a number discriminant diagrams (Al2O3 — TiO2, Zr Y/Ni Cr/V, Cr/Th Th/Sc, etc.). It is shown that data points individual rock samples on most form fairly compact area in which their sets, belonging to different strata, have significant overlap. In diagram F1 F2, are present all its...
Objective: lymph node metastases occur in 90% of cases patients with gastric adenocarcinoma, and survival is less than 15% the late stages disease. Therefore, purpose study was to screening markers for predicting likelihood developing adenocarcinoma. Materials methods: 47 diagnosis adenocarcinoma were used (with localized tumor form T3-4N0M0 (n = 18) locally distributed T3-4N1-3M0 29)). The copy number variation 16 genes (APC, AURKA, CCND1, C-MYC, GKN1, HER2, IRX1, MDM2, MET, NFKB, OCT1,...
Objective: to define a role of renal reperfusion lesion in the development failure cancer patients after elimination longstanding urinary tract occlusion. Subjects and methods. The study covered 26 whom disease was complicated by obstruction with evolving failure. All received surgical treatment aimed at eliminating In early postoperative period, progression dysfunction seen all cases. time course changes microcirculation, gas exchange, oxidative-antioxidative balance, function were...
Purpose of the study . The purpose was to find difference between local levels VEGF, EGF, IGFI and IG- FII in tumor intact tissues adenocarcinoma stomach (AC) signet-ring cell carcinoma (SRCC). Materials methods Levels EGFR, IGF-I IGFII were determined by ELISA gastric 15 AC patients 10 SRCC (T 2-3 N 0-2 M 0 , G2-3), mean age 62.8±2.38 years. Results IGF-I, IGF-II VEGF similar at SRCC, but EGF EGFR higher than SRCC. Level tissue, compared increased 2.3 times decreased 2.1 1.8 times,...
Aim. To study the prevalence of carriage polymorphic allele variants genes blood coagulation factors in oncological patients.
 Materials and Methods. 213 Patients with morphologically confirmed diseases were examined. Samples genomic DNA peripheral patients Using polymerase chain reaction (PCR), sites hemostatic system studied real time: F2 (G20210А, rs1799963), F5 (G1691A, rs6025), F7 (G10976A, rs6046), F13 (G226A, rs5985), FGB G(-455)A (rs1800790), ITGA2-2 (C807T, rs1126643), ITGB3-b...
Purpose of the study. To analyze immediate outcomes following surgical treatment locally advanced malignant non-organ retroperitoneal tumors (NRT). Materials and methods. Surgical interventions for NRTs were performed in 114 patients at Abdominal Oncology Department № 1, National Medical Research Centre Oncology.There 48 males 66 females among them. According to histological structure, liposarcoma was commonly detected 64 (56.1 %) cases. Results. Intraoperative revision revealed spread tumor...
Objective. Cancer of the oral mucosa is frequently detected only at stages III and IV disease despite visual accessibility tumor in 37.6% total number cases, resulting recurrence being main problem after completion primary treatment these patients. The search for interventions to improve efficacy locally advanced tumors ongoing. Material methods. Twelve patients with cancer T3-4aN0-2M0 underwent radical excision intraoperative photodynamic therapy (PDT). device “Latus-T Fara” following...
Objective. To study level and structure of microbial colonization in cancer patients before admission to a surgery department using molecular methods. Materials Methods. The presence DNA methicillin-resistant Staphylococcus aureus, methicillinresistant coagulase-negative staphylococci, Candida albicans/C. glabrata/C. krusei, Acinetobacter baumannii the clinical specimens antimicrobial resistance genes cultures were detected by multiplex real-time PCR. A total 741 samples 313 studied....
Aim. To evaluate results of venous resections in tumor infiltration wall pancreatic cancer (PC).
 Materials and Methods. The study included 74 patients with PC invasion the mesenteric-portal system (T3 N0-1 M0). control group (n=53), receiving palliative chemotherapy. average age surgical treatment was 61.89.8 years, 63.210.1 years (р0.05), diameter 39 mm 43 mm, respectively (р0.05). In 62 cases located head pancreas (P), were conducted pancreaticoduodenal resection resection. rest...
The purpose was to study the structural and functional parameters of erythrocyte membranes in blood patients with gastric cancer (GC) – adenocarcinoma, depending on its grade, signet ring cell carcinoma (SRCC), combined lesions (CGL). Materials methods . membrane fluidity area lipid bilayer protein-lipid contacts, polarity immersion proteins matrix red cells were evaluated by fluorimetry using hydrophobic pyrene-based probe. included 86 GC divided into six groups: well-...