- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Cardiac, Anesthesia and Surgical Outcomes
- ECG Monitoring and Analysis
- Machine Learning in Healthcare
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Trace Elements in Health
- Cerebral Palsy and Movement Disorders
- Diabetic Foot Ulcer Assessment and Management
- Burn Injury Management and Outcomes
- Tuberculosis Research and Epidemiology
- Neurological disorders and treatments
- Metabolism, Diabetes, and Cancer
- Chemotherapy-induced cardiotoxicity and mitigation
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Iron Metabolism and Disorders
- Hepatitis C virus research
- Cardiac and Coronary Surgery Techniques
- Drug-Induced Hepatotoxicity and Protection
- Explainable Artificial Intelligence (XAI)
- Estrogen and related hormone effects
University of British Columbia
2023
University of Manitoba
2018-2022
Health Sciences Centre
2022
North Middlesex Hospital
2021
Middlesex University
2021
Winnipeg Regional Health Authority
2018
Research Manitoba
2011-2018
St. Boniface Hospital
2018
Toronto Public Health
2016-2017
Acute kidney injury (AKI) following cardiac surgery leads to increased morbidity and mortality. Characterization validation of early biomarkers AKI may ultimately facilitate therapeutic intervention. We have previously identified that elevated urinary hepcidin-25 is inversely independently associated with the development in adult patients. Hepcidin-25 an antimicrobial peptide sequesters iron intracellularly, its elevation human ischemia reperfusion represent a renoprotective response...
Background: Two anti-cancer agents, doxorubicin (DOX) and trastuzumab (TRZ), are commonly used in the management of breast cancer women. Despite their efficacy reducing morbidity mortality individuals with cancer, use these agents is limited by adverse cardiotoxic side effects. Both nutraceutical agent flaxseed (FLX) pharmaceutical drug perindopril (PER) have been studied individually prevention chemotherapy-mediated cardiac dysfunction. The objective this study was to determine whether...
Evidence regarding the incremental benefit of cardiac resynchronization therapy (CRT) with a defibrillator (CRT-D) versus without (CRT-P) in elderly patients heart failure is limited. We compared mortality and hospitalisation between CRT-D CRT-P elderly.A retrospective chart review identified all consecutive age ≥75 CRT implantation over last 10 years at Canadian tertiary care centre. Kaplan-Meier survival analyses cumulative incidence curves were used to compare time first hospitalisation,...
<h3>Introduction</h3> Tuberculosis was the leading cause of mortality from infectious disease until covid-19 pandemic. Over a quarter world's population is estimated to have latent tuberculosis infection (LTBI), with 5–10% expected develop active TB. Hepatotoxicity well described side-effect anti-tuberculosis medication, often disruptions in treatment. Currently, NICE guidelines recommend careful liver function test (LFT) monitoring patients on medication disease, abnormal baseline LFTs or...
Background: Cardiac Implantable Electronic Devices (CIED) include pulse generators and leads. In some implanting centres, it is common practice to combine devices with leads from different companies. Case series have reported episodic high-impedance changes in Boston Scientific CIEDs competitor We investigated the incidence of abnormalities matched vs. mismatched CIEDs. Methods: Retrospective chart review identified all consecutive Accolade pacemakers Autogen implantable cardioverter...