Simon Christie

ORCID: 0000-0003-4910-6693
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About
Contact & Profiles
Research Areas
  • Cardiac pacing and defibrillation studies
  • Cardiac Arrhythmias and Treatments
  • Cardiac Valve Diseases and Treatments
  • Aortic aneurysm repair treatments
  • Aortic Disease and Treatment Approaches
  • Cardiac, Anesthesia and Surgical Outcomes
  • ECG Monitoring and Analysis
  • Machine Learning in Healthcare
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Trace Elements in Health
  • Cerebral Palsy and Movement Disorders
  • Diabetic Foot Ulcer Assessment and Management
  • Burn Injury Management and Outcomes
  • Tuberculosis Research and Epidemiology
  • Neurological disorders and treatments
  • Metabolism, Diabetes, and Cancer
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Coronary Interventions and Diagnostics
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Iron Metabolism and Disorders
  • Hepatitis C virus research
  • Cardiac and Coronary Surgery Techniques
  • Drug-Induced Hepatotoxicity and Protection
  • Explainable Artificial Intelligence (XAI)
  • Estrogen and related hormone effects

University of British Columbia
2023

University of Manitoba
2018-2022

Health Sciences Centre
2022

North Middlesex Hospital
2021

Middlesex University
2021

Winnipeg Regional Health Authority
2018

Research Manitoba
2011-2018

St. Boniface Hospital
2018

Toronto Public Health
2016-2017

Acute kidney injury (AKI) following cardiac surgery leads to increased morbidity and mortality. Characterization validation of early biomarkers AKI may ultimately facilitate therapeutic intervention. We have previously identified that elevated urinary hepcidin-25 is inversely independently associated with the development in adult patients. Hepcidin-25 an antimicrobial peptide sequesters iron intracellularly, its elevation human ischemia reperfusion represent a renoprotective response...

10.1177/2054358117744224 article FR cc-by-nc Canadian Journal of Kidney Health and Disease 2018-01-01

Background: Two anti-cancer agents, doxorubicin (DOX) and trastuzumab (TRZ), are commonly used in the management of breast cancer women. Despite their efficacy reducing morbidity mortality individuals with cancer, use these agents is limited by adverse cardiotoxic side effects. Both nutraceutical agent flaxseed (FLX) pharmaceutical drug perindopril (PER) have been studied individually prevention chemotherapy-mediated cardiac dysfunction. The objective this study was to determine whether...

10.3390/curroncol29050241 article EN cc-by Current Oncology 2022-04-21

Evidence regarding the incremental benefit of cardiac resynchronization therapy (CRT) with a defibrillator (CRT-D) versus without (CRT-P) in elderly patients heart failure is limited. We compared mortality and hospitalisation between CRT-D CRT-P elderly.A retrospective chart review identified all consecutive age ≥75 CRT implantation over last 10 years at Canadian tertiary care centre. Kaplan-Meier survival analyses cumulative incidence curves were used to compare time first hospitalisation,...

10.1002/joa3.12131 article EN cc-by-nc-nd Journal of Arrhythmia 2018-11-14

<h3>Introduction</h3> Tuberculosis was the leading cause of mortality from infectious disease until covid-19 pandemic. Over a quarter world's population is estimated to have latent tuberculosis infection (LTBI), with 5–10% expected develop active TB. Hepatotoxicity well described side-effect anti-tuberculosis medication, often disruptions in treatment. Currently, NICE guidelines recommend careful liver function test (LFT) monitoring patients on medication disease, abnormal baseline LFTs or...

10.1136/thorax-2021-btsabstracts.150 article EN cc-by-nc-sa 2021-11-01
Christopher B. Fordyce Andreas H. Kramer Craig Ainsworth Jim Christenson Gary R. Hunter and 95 more Julie Kromm Carmen Soto Damon C. Scales Mypinder S. Sekhon Sean van Diepen Laura Dragoi Colin B. Josephson Demetrios J. Kutsogiannis Michel Le May Christopher B. Overgaard Martin Savard Gregory Schnell Graham C. Wong Emilie Belley-Côt Tadeu A. Fantaneanu Christopher B. Granger Adriana Luk Rebecca Mathew Victoria McCredie Laurel Murphy Jeanne Teitelbaum Brian Grunau Gurmeet Singh Jan Elohlávek Demetris Yannopoulos Joseph E. Tonna Alice Hutin Dave Nagpal Alexis Cournoyer Madeleine Barker Konstantin A. Krychtiuk Carlos L. Alviar Richard Jung Pietro Di Santo Trevor Simard Simon Parlow Willy Weng Omar Abdel‐Razek Nikita Malhotra Matthew C. Cheung Jordan Hutson Jeffrey A. Marbach Pouya Motazedian Michael Thibert Shannon M. Fernando Pablo B. Nery Girish M. Nair Juan Russo Benjamin Hibbert F. Daniel Ramirez Simon Christie Marc W. Deyell Christopher Barnett Samuel B. Brusca Thomas C. Hanff Vanessa Blumer Adnan Kalif Manreet Kanwar Zachary Singer Marat Slessarev Daniel Durocher Michael P. Ward Jacob C. Jentzer Jaime Hernández-Montfort Thomas M. Roston Derek So Shuangbo Liu Akshay Bagai Shaun G. Goodman Étienne Couture Pascal Laferrière-Langlois Andr� Denault Martin Girard Jean Deschamps Saad Razzaq Nicolas Lavoie William Beaubien–Souligny Riendeau Geneviève Felipe Beaulac Vincent Lecluyse A. Costescu Marc Bélliveau Georges Desjardins Mahsa Elmi-Sarabi Ephanie Jarry Elena Saade Alexander Calderone Cristhian Potes Varinder K. Randhawa Ana Spataru Lindsay Jory Fuad Moussa Anju Bhardwaj Indranee Rajapreyar Caroline R. Gross

10.1016/s0828-282x(23)00218-0 article EN Canadian Journal of Cardiology 2023-04-01

10.1097/00004630-200001001-00224 article EN Journal of Burn Care & Rehabilitation 2000-01-01

Background: Cardiac Implantable Electronic Devices (CIED) include pulse generators and leads. In some implanting centres, it is common practice to combine devices with leads from different companies. Case series have reported episodic high-impedance changes in Boston Scientific CIEDs competitor We investigated the incidence of abnormalities matched vs. mismatched CIEDs. Methods: Retrospective chart review identified all consecutive Accolade pacemakers Autogen implantable cardioverter...

10.22541/au.163250889.98234088/v1 preprint EN Authorea (Authorea) 2021-09-24
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