Mariola Marchlewicz

ORCID: 0000-0003-4915-9875
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About
Contact & Profiles
Research Areas
  • Heavy Metal Exposure and Toxicity
  • Sperm and Testicular Function
  • Hormonal and reproductive studies
  • Trace Elements in Health
  • Reproductive Biology and Fertility
  • Estrogen and related hormone effects
  • Sexual Differentiation and Disorders
  • Psoriasis: Treatment and Pathogenesis
  • Dermatology and Skin Diseases
  • Phytoestrogen effects and research
  • Birth, Development, and Health
  • Effects and risks of endocrine disrupting chemicals
  • Mercury impact and mitigation studies
  • Hematopoietic Stem Cell Transplantation
  • Skin Protection and Aging
  • Vitamin C and Antioxidants Research
  • Immunotoxicology and immune responses
  • Fatty Acid Research and Health
  • Testicular diseases and treatments
  • Antioxidant Activity and Oxidative Stress
  • Consumer Packaging Perceptions and Trends
  • melanin and skin pigmentation
  • Immune Response and Inflammation
  • Fluoride Effects and Removal
  • Neonatal Health and Biochemistry

Pomeranian Medical University
2016-2025

University of Szczecin
2011-2021

Szczecin Academy of Arts
2001

Akademia Pomorska w Słupsku
1994

Psoriasis is a common chronic, inflammatory skin disease characterised by keratinocyte hyperproliferation, parakeratosis, and T-cell infiltration. Adipose tissue has an endocrine function, producing abundance of cytokines adipokines. It also been described that the major adipokines, leptin, resistin, adiponectin, may be involved in pathogenesis psoriasis. The aim study was to examine plasma levels resistin patients with psoriasis their correlations activity parameters: Activity Severity...

10.3390/jcm12020663 article EN Journal of Clinical Medicine 2023-01-13

Background: The pathogenesis of psoriasis is poorly understood. Increased reactive oxygen species (ROS) and lipid peroxidation are crucial in the inflammatory processes, including psoriasis. Thus, microelements, such as zinc copper, may play a significant role this disease's development. Methods: Due to paucity inconsistency literature data, we studied levels copper blood serum from 301 unselected psoriatic patients matched healthy controls examined any associations among microelements...

10.3390/biomedicines13020529 article EN cc-by Biomedicines 2025-02-19

Abstract Pyruvic acid and its derivatives occurring in most biological systems are known to exhibit several pharmacological properties, such as anti‐inflammatory, neuroprotective or anticancer, many of which suggested originate from their antioxidant free radical scavenger activity. The therapeutic potential these compounds is a matter particular interest, due mechanisms action, particularly possible behaviour. Here, we report the results study effect pyruvic (PA), ethyl pyruvate (EP) sodium...

10.1002/bio.2879 article EN Luminescence 2015-03-08

Psoriasis is a chronic systemic disease with multifaceted pathomechanism and immunological basis, the presence of inflammatory skin lesions joint ailments. Diseases accompanying psoriasis include metabolic cardiovascular disorders. It has been suggested that inflammation involved in development each these conditions. The main objective this study was to analyse fatty acid profile, including polyunsaturated acids, erythrocyte membranes patients suffering from psoriasis. A total 58 adult...

10.3390/nu16121799 article EN Nutrients 2024-06-07

The aim of the study was to evaluate effect insulin-like growth factors (IGF1 and IGF2), stem cell factor (SCF) epidermal (EGF) on development embryos exposed oxidative stress. C3B6F1 female mice were stimulated with 5 IU pregnant mare serum gonadotropin equine chorionic (eCG). Two-cell flushed out from fallopian tubes 40 h after eCG administration mating DBA males. In each experiment divided into three groups cultured in (1) control medium, (2) medium 0.1 mM hydrogen peroxide (3) separately...

10.1017/s0967199404002783 article EN Zygote 2004-08-01

Dietary fat has been inconsistently associated with the risk of breast cancer. The purpose this study was to examine relationship between meat and animal plant intake cancer in subgroups by total lifetime physical activity, using data from a case-control conducted Region Western Pomerania, Poland.The included 858 women histological confirmed 1,085 controls, free any diagnosis. based on self-administered questionnaire including questions about socio-demographic characteristics, current weight...

10.7314/apjcp.2013.14.4.2495 article EN cc-by Asian Pacific Journal of Cancer Prevention 2013-04-30

In rats with a DHT deficiency induced by finasteride, morphological changes in the seminiferous epithelium were observed. The structural alterations manifested premature germ cells sloughing into lumen of tubules. etiology this disorder could be connected intercellular junctions disintegration. We showed immunohistochemical study expression some proteins building tight and adherens junctions. depression N-cadherin, β-catenin occludin immunoexpressions reason for release immature from...

10.5603/fhc.2011.0010 article EN cc-by-nc-nd Folia Histochemica et Cytobiologica 2011-04-19
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