- Sleep and related disorders
- Infant Development and Preterm Care
- Sleep and Wakefulness Research
- Circadian rhythm and melatonin
- Birth, Development, and Health
- Maternal Mental Health During Pregnancy and Postpartum
- Infant Health and Development
- Neuroscience of respiration and sleep
- Obesity, Physical Activity, Diet
- Vitamin D Research Studies
- Cystic Fibrosis Research Advances
- Microbial Metabolism and Applications
- Child Nutrition and Water Access
- Meat and Animal Product Quality
- Early Childhood Education and Development
- Amino Acid Enzymes and Metabolism
- Nutritional Studies and Diet
- Oral microbiology and periodontitis research
- Cardiac, Anesthesia and Surgical Outcomes
- Congenital Heart Disease Studies
- Fermentation and Sensory Analysis
- Metabolism and Genetic Disorders
- Child Nutrition and Feeding Issues
- Dental Health and Care Utilization
- Educational Methods and Impacts
Shanghai Children's Medical Center
2015-2022
Henan University
2022
Henan University of Economic and Law
2022
Shanghai Jiao Tong University
2015-2021
XinHua Hospital
2019-2021
Shenyang Normal University
2019
To examine trajectories of poor sleep quality from late pregnancy to 36 months postpartum, baseline indicators, and association with prospective maternal mood disturbances. A cohort 262 nonclinical women was followed at pregnancy, 42 days, 3, 6, 9, 12, 18, 24, postpartum. Sleep measured the Pittsburgh Quality Index all time points, disturbances were assessed The rate an inverted U-shaped curve. Women reporting held a consistently higher risk postpartum points. Three distinguished, namely,...
Daqu is an important saccharification starter in the brewing of Chinese Baijiu. The evolution microbial communities and flavor formation are similar among different batches Daqu, but drivers community succession, composition functional microbiota, metabolic pathways still unclear. To this end, physicochemical properties volatile metabolites dynamic changes their correlation during fermentation process Taorong-type Baijiu were analyzed. results showed that core genera observed whole period...
This study aimed to investigate a gender-specific association between oral health-related quality of life (OHRQoL) and depressive symptoms in college students, as there are limited relevant studies conducted among youths.
Abstract Sleep and circadian rhythmicity both play an important role in human’s cognitive functioning, yet the way which early development of sleep rhythm affects processes social learning infants remains less understood. We examined association activity (CAR) with face emotional information processing 12-month old infants. Face was measured by eye tracking, whereby infants’ scanning patterns pupil dilations were calculated when they presented neutral, pleasant unpleasant faces. Infants...
Wearable devices have been widely used in clinical studies to study daily activity patterns, but the analysis remains a major obstacle for researchers.This proposes novel method characterize sleep-activity rhythms using actigraphy and further use it describe early childhood rhythm formation examine its association with physical development.We developed machine learning-based Penalized Multiband Learning (PML) algorithm sequentially infer dominant periodicities based on Fast Fourier Transform...
Abstract Background Sleep disturbances in women occur frequently throughout pregnancy. Previous studies have demonstrated that the increasing incidence of physiological and psychological illness is concurrent with sleep deprivation poor quality adults children. Objectives The Shanghai Birth Cohort Study (SSBCS) was established to examine effect during third trimester on emotional regulation mothers; assess maternal pregnancy growth development children; explore influence children's...
The relationship between vitamin D and cardiovascular health in children remains unclear. Vitamin deficiency (VDD) is supposed to be a potential risk factor associated with poorer outcomes after congenital heart disease (CHD) surgery. maximum vasoactive-inotropic use cardiac surgery considered good predictor of adverse outcomes. We aimed assess the correlation preoperative VDD score (VIS max ) at 24 h postoperatively. Nine hundred CHD were enrolled this study, total serum 25-hydroxyvitamin...
Purpose To fulfil the needs of assessment tools in Chinese population, we adapted LENA Developmental Snapshot, a parent survey that measures early language and communication development English-speaking children. We reported psychometric properties questionnaire evaluated metric functional equivalence between original instruments.Method The Snapshot was translated into reviewed by an expert panel. English-specific items (e.g. past tense, plural) were mapped onto functionally similar Mandarin...
Objective: To investigate the current bedtime routine among Chinese children less than 3 years of age and explore its dose-dependent association with sleep duration quality. Method: Healthy full-term born aged 0-35 months were selected by stratified cluster random sampling method from 8 provinces in China following "Hospital Province-City-County" technical route during 2012-2013.Brief Infant Sleep Questionnaire(BISQ) was used to assess conditions these children.Children's personal family...
Background: Primary ciliary dyskinesia (PCD) is a rare genetically heterogeneous disorder of motile cilia. Common features PCD include upper and lower respiratory tract disease, secretory otitis media, situs inversus fertility problems. To date, although several PCD-associated genes have been identified, the genetic causes most cases remain elusive. Methods: In this case study, we analyzed clinical data one monochorionic diamniotic twins which were suspected having on basis radiological...
Abstract Background : Prior studies suggested that rapid weight change in infancy is associated with increased childhood and adulthood status. However, the trajectory early life over time extent to which lifestyle behaviors may modify risk of infant are not completely understood. Our aims were characterize explore its independent/combined effects factors on adiposity outcomes at four years age. Methods In our ongoing birth cohort study, we used nine follow-up points (birth, 3, 6, 9, 12, 18,...
Abstract Background Wearable devices have been widely used in clinical studies to study daily activity patterns, but the analysis remains major obstacle for researchers. Study Objective This proposed a novel method characterize sleep-activity rhythms using actigraphy and further it describe early childhood rhythm formation examine its association with physical development. Methods We developed machine learning-based Penalized Multi-band Learning (PML) algorithm sequentially infer dominant...
<sec> <title>BACKGROUND</title> Wearable devices have been widely used in clinical studies to study daily activity patterns, but the analysis remains a major obstacle for researchers. </sec> <title>OBJECTIVE</title> This proposes novel method characterize sleep-activity rhythms using actigraphy and further use it describe early childhood rhythm formation examine its association with physical development. <title>METHODS</title> We developed machine learning–based Penalized Multiband Learning...
Abstract Objectives Glycine decarboxylase gene ( GLDC ) mutations cause nonketotic hyperglycinemia (NKH). Patients of NKH usually have heterogeneous phenotypes including respiratory failure, lethargy, myoclonic jerks, and hypotonia. The excessive glycine accumulation in brain is a crucial pathogenic mechanism. Methods We performed clinical phenotypic analysis two Chinese patients conducted whole exome sequencing to detect possible genes. Transcriptional experiments were carried out evaluate...