Alodia Lacueva

ORCID: 0000-0003-4970-2460
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About
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Research Areas
  • 3D Printing in Biomedical Research
  • Additive Manufacturing and 3D Printing Technologies
  • Microfluidic and Bio-sensing Technologies
  • Renal and related cancers
  • Cancer Cells and Metastasis
  • Graphene and Nanomaterials Applications
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Dialysis and Renal Disease Management
  • Viral Infections and Vectors
  • Pluripotent Stem Cells Research
  • Aluminum Alloy Microstructure Properties
  • Health and Medical Research Impacts
  • Heart Rate Variability and Autonomic Control
  • Cancer, Hypoxia, and Metabolism
  • Microfluidic and Capillary Electrophoresis Applications
  • Molecular Communication and Nanonetworks
  • Additive Manufacturing Materials and Processes
  • Cancer Genomics and Diagnostics
  • Tissue Engineering and Regenerative Medicine
  • Renal cell carcinoma treatment
  • Chronic Kidney Disease and Diabetes
  • Viral Infectious Diseases and Gene Expression in Insects
  • Organ Donation and Transplantation
  • Cell Image Analysis Techniques

Universidad de Zaragoza
2016-2024

University of Castilla-La Mancha
2024

Instituto de Investigación Sanitaria Aragón
2022-2024

Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine
2016

Universidad de Extremadura
2016

Abstract The physical microenvironment of tumours is characterized by heterotypic cell interactions and physiological gradients nutrients, waste products oxygen. This tumour has a major impact on the biology cancer cells their response to chemotherapeutic agents. Despite this, most in vitro research still relies primarily grown 2D isolation nutrient- oxygen-rich conditions. Here, microfluidic device presented that easy use enables modelling study real-time. versatility this platform allows...

10.1038/srep36086 article EN cc-by Scientific Reports 2016-10-31

The tumour microenvironment (TME) has recently drawn much attention due to its profound impact on development, drug resistance and patient outcome. There is an increasing interest in new therapies that target the TME. Nonetheless, most established vitro models fail include essential cues of Microfluidics can be used reproduce TME hence provide valuable insight evolution sensitivity. However, microfluidics remains far from well-established mainstream molecular cell biology methods. Therefore,...

10.1038/s41598-019-42529-8 article EN cc-by Scientific Reports 2019-04-17

A kidney-on-a-chip has been developed and optimised to evaluate the effects of exposure graphene related materials under fluid flow conditions.

10.1039/d4nh00064a article EN cc-by-nc Nanoscale Horizons 2024-01-01

Nephrotoxicity stands as one of the most limiting effects in development and validation new drugs. The kidney, among organs evaluated toxicity assessments, has a higher susceptibility, with nephrotoxic potential frequently evading detection until late clinical trials. Traditional cell culture, which been widely used for decades, does not recapitulate structure complexity native tissue, can affect function, response to cytotoxins resemble what occurs kidney. In current study, we aimed address...

10.3390/biomimetics9070446 article EN cc-by Biomimetics 2024-07-22

Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL DOI

10.2139/ssrn.4797903 preprint EN 2024-01-01

Póster presentado en la IX Jornada de Jóvenes Investigadores del I3A

10.26754/jjii3a.4966 article ES Jornadas de jóvenes investigadores del I3A 2020-12-22

Study Objective Renal proximal tubules are exposed in vivo to physiological levels of shear stress. We aim determine how preconditioning human tubule cells with stress affects their sensibility hypoxia or ischemia. Hypothesis Physiological would induce further differentiation and metabolic specialization resulting changes response low oxygen nutrient conditions. Methods Immortalized (RPTEC-TERT1 from Evercyte) were grown confluence Ibidi µSlides then for three days two flow regimes providing...

10.1096/fasebj.2021.35.s1.05438 article EN The FASEB Journal 2021-05-01
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