A5083831445- Gastric Cancer Management and Outcomes
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Drug Transport and Resistance Mechanisms
- Parathyroid Disorders and Treatments
- Fibroblast Growth Factor Research
- Genetic Syndromes and Imprinting
- Circular RNAs in diseases
- Esophageal Cancer Research and Treatment
- Cancer-related gene regulation
- Thyroid and Parathyroid Surgery
- Neuroblastoma Research and Treatments
- Lymphoma Diagnosis and Treatment
- Kruppel-like factors research
- Magnesium in Health and Disease
- Cancer Mechanisms and Therapy
- Neuroendocrine Tumor Research Advances
- Advanced Breast Cancer Therapies
- Lung Cancer Research Studies
- RNA Research and Splicing
Hebei Medical University
2014-2024
Fourth Hospital of Hebei Medical University
2018-2024
Hangzhou Hospital of Traditional Chinese Medicine
2024
Abstract Background In the FIGHT study (NCT03694522) bemarituzumab, a humanized monoclonal antibody selective for fibroblast growth factor receptor 2b (FGFR2b), plus mFOLFOX6 showed clinically meaningful efficacy in patients with FGFR2b-positive (2+/3+ membranous staining by immunohistochemistry) locally advanced unresectable/metastatic gastric/gastroesophageal cancer (G/GEJC). A proportion of were enrolled East Asia, reflecting global epidemiology G/GEJC. Methods This subgroup analysis...
Background Although favorable outcomes have been reported with radiofrequency ablation (RFA) for secondary hyperparathyroidism (SHPT), the long-term efficacy remains insufficiently investigated. Purpose To evaluate and safety of US-guided percutaneous RFA in patients SHPT undergoing dialysis to identify possible predictors associated treatment failure. Materials Methods This retrospective study included consecutive at least one enlarged parathyroid gland accessible who were seven tertiary...
Gastric cancer (GC) is a leading cause of global cancer-related death. The incidence and mortality rates gastric in China are second third ranked all forms malignant tumors. Krüppel-like factor11 (KLF11) member the KLF family, previous studies have shown it significantly influences epithelial ovarian, pancreatic liver proliferation, differentiation apoptosis. However, expression some biological functions KLF11 GC still unclear. We therefore collected analyzed mRNA protein expressions 59...
Extranodal NK/T-cell lymphoma nasal type (ENKTL) is a subtype of T cell with poor prognosis. In this study, we designed new prognostic model specifically for ENKTL to improve the risk stratification. 29 patients, screened mutations in 9 ENKTL-associated genes using next-generation sequencing (NGS). We have found that mutated KMT2D was associated inferior overall survival (OS) and progression free (PFS) or TP53 were higher mortality rate. Moreover, difference PFS among different...
Abstract Background Surgical staplers have been widely used to facilitate surgeries, and this study aimed examine the real-world effectiveness of a new powered stapling system with Gripping Surface Technology (GST) on intraoperative outcomes gastrectomy for gastric cancer. Method The data were extracted from Fourth Hospital Hebei Medical University’s (FHHMU) medical records system. Participants (N = 121 patients) classified into GST (n 59) or non-GST group 62), based use such as bleeding...
Objective: Biological behavior, pathological characteristics and prognostic factors of 355 cases with gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) were analyzed in this retrospective study. Methods: In our study, patients pathologically diagnosed as GEP-NENs identified from April 2006 to November 2017 the Fourth Hospital Hebei Medical University. The biological prognosis retrospectively. Results: There (228 males 127 females) a mean age 58.3±10.7 years. detected most frequently...
Objective: To investigate the clinical value of pT2 gastric cancer staging pT2a and pT2b according to depth muscularis propria invasion in evaluating prognosis cancer. Methods: According 8th edition TNM system for proposed by Union International Cancer Control (UICC) American Joint Committee on (AJCC), patients with who underwent radical surgery Fourth Hospital Hebei Medical University from January 1, 2008 2015 were selected divided into stage group tumor invasion. The 5-year overall...