A5033623253- SARS-CoV-2 and COVID-19 Research
- Cancer-related gene regulation
- Voice and Speech Disorders
- COVID-19 Clinical Research Studies
- Macrophage Migration Inhibitory Factor
- Respiratory and Cough-Related Research
- Galectins and Cancer Biology
- Machine Learning in Bioinformatics
- Flavonoids in Medical Research
- Pediatric Hepatobiliary Diseases and Treatments
- Computational Drug Discovery Methods
- Cancer Mechanisms and Therapy
- Liver Disease Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Immune cells in cancer
- Click Chemistry and Applications
- Music and Audio Processing
- RNA modifications and cancer
- Speech Recognition and Synthesis
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Inflammasome and immune disorders
- Organ Transplantation Techniques and Outcomes
Hebei Provincial Center for Disease Control and Prevention
2024
Nantong University
2024
Dalian Medical University
2024
Hefei Institutes of Physical Science
2023
Anhui University
2023
Chinese Academy of Sciences
2023
Guangzhou University of Chinese Medicine
2022-2023
Guangdong Provincial Hospital of Traditional Chinese Medicine
2022
Ductular reaction (DR) is usually observed in biliary disorders or various liver disorders, including nonalcoholic fatty disease. Few studies have focused on interrupting the DR process cholestatic environment. Here, we investigated impact of reversine rats that had undergone bile duct ligation (BDL). Cholestatic injury was induced 2 weeks following BDL. assessed with markers by immunohistochemistry. Biliary epithelial cells (BECs) were isolated for analysis proliferation and factor gene...
Radix Scutellariae (RS) has been used to treat influenza for thousands of years in China. However, its mechanisms action remain unclear. The aim the present study was use a network pharmacology and molecular docking-based approach explore active components potential RS A.Target genes A were attained by accessing databases. We then determined intersection both through bioinformatics using R Perl language. protein-protein interaction (PPI) constructed STRING website (https://cn.string-db.org)....
Lung adenocarcinoma (LUAD)poses substantial therapeutic complexities due to its resistance first-line chemotherapic agents such as paclitaxel. This study investigated the involvement of NRAS in development paclitaxel LUAD. We integrated transcriptome data from TCGA and other databases while conducting vitro experiments also used GSEA identify NRAS-related genes pathways. Our findings revealed a significant up-regulation LUAD tissue, with higher expression correlating adverse patient outcomes...
<title>Abstract</title> Lung adenocarcinoma (LUAD)poses substantial therapeutic complexities due to its resistance first-line chemotherapic agents such as paclitaxel. This study investigated the involvement of NRAS in development paclitaxel LUAD. We integrated transcriptome data from TCGA and other databases while conducting vitro experiments also used GSEA identify NRAS-related genes pathways. Our findings revealed a significant up-regulation LUAD tissue, with higher expression correlating...
Objective: Notch-1 is a signal regulatory protein with extensive effects in myeloid cells, but its role aneurysms remains to be fully clarified. In this study, therefore, the aneurysm mouse model myeloid-specific knockout of was established observe progression. Methods and Results: The effect assessed by pathological staining Western blotting. It found that after model, area macrophage infiltration were significantly reduced, damage arterial elastic plates relieved, oxidative stress level...
Kumquat decoction is a traditional Chinese medicine formula and has been widely used to alleviate the coronavirus disease 2019 (COVID-19)-related cough in China. However, effectiveness safety of kumquat remain unclear. To assess for COVID-19-related cough. A multicentre, prospective observational study. We enrolled consecutive patients with mild-to-moderate COVID-19 from December 31, 2022, January 3, 2023, during Omicron phase Yangshuo County, The primary outcome was time study baseline...
Alzheimer's disease (AD) is the most prevalent type of dementia and can cause abnormal cognitive function progressive loss essential life skills. Early screening thus necessary for prevention intervention AD. Speech dysfunction an early onset symptom AD patients. Recent studies have demonstrated promise automated acoustic assessment using or linguistic features extracted from speech. However, previous relied on manual transcription text to extract features, which weakens efficiency...