Chen Cha

ORCID: 0000-0001-7297-2202
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About
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Research Areas
  • Cancer Research and Treatments
  • Pneumonia and Respiratory Infections
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Immunodeficiency and Autoimmune Disorders
  • Neurological Complications and Syndromes
  • Immunotherapy and Immune Responses
  • Inflammatory Biomarkers in Disease Prognosis
  • Mycobacterium research and diagnosis
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial Identification and Susceptibility Testing
  • Tuberculosis Research and Epidemiology
  • Travel-related health issues
  • Dermatology and Skin Diseases
  • Neonatal and fetal brain pathology
  • Connective Tissue Growth Factor Research
  • Advanced Technologies in Various Fields
  • Clinical Laboratory Practices and Quality Control
  • Neurological Disease Mechanisms and Treatments
  • Medicinal Plant Pharmacodynamics Research
  • Viral Infectious Diseases and Gene Expression in Insects
  • Intracranial Aneurysms: Treatment and Complications
  • Bacterial Infections and Vaccines
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Chronic Kidney Disease and Diabetes
  • Viral Infections and Outbreaks Research

Guangzhou University of Chinese Medicine
2020-2025

Southern Medical University
2023

South China University of Technology
2023

Bridge University
2023

Sun Yat-sen University
2023

Chinese PLA General Hospital
2014-2015

China National Petroleum Corporation (China)
2014

Community Health Center
2014

Second Hospital of Tianjin Medical University
2013

Tianjin Medical University
2013

Atopic dermatitis (AD) is a multifactorial, chronic relapsing disease. Staphylococcus aureus the key microbial factor in AD, linked to disease activity. However, there limited knowledge of genomic prevalence characteristics and phenotypic features S. AD patients China. We investigated 108 China globally publicly available genome sequences 579 AD. Sequence type (ST) 7, ST15 ST188 were major lineages Genes esaC, esxB, sea only detected ST7, potentially contributing its exhibited high virulence...

10.1038/s41598-025-87317-9 article EN cc-by-nc-nd Scientific Reports 2025-02-08

Abstract Background and purpose Whether symptomatic unruptured intracranial aneurysms (UIAs) lead to change in circulating inflammation remains unclear. This study aims evaluate the role of hematological inflammatory indicators predicting UIA. Methods Adult patients diagnosed with saccular aneurysm from March 2019 September 2023 were recruited retrospectively. Clinical laboratory data, including white blood cells (WBC), neutral counts (NEUT), lymphocyte (LYM), monocyte (MONO) each patient,...

10.1186/s40001-023-01608-3 article EN cc-by European journal of medical research 2024-01-11

Abstract Background The surveillance system revealed that the prevalence of vancomycin-resistant Enterococcus faecium (VREfm) has increased. We aim to investigate epidemiological and genomic characteristics VREfm in China. Methods collected 20747 non-redundant E. isolates from inpatients across 19 hospitals six provinces between Jan 2018 June 2023. was confirmed by antimicrobial susceptibility testing. analyzed using changepoint package R. Genomic were explored whole-genome sequencing...

10.1101/2024.03.20.24304567 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-03-20

Abstract Background To detect the serum antibodies against respiratory viruses and atypical pathogens in adults with community‐acquired pneumonia (CAP) Guangzhou City (Guangdong province, China). Methods A retrospective study was carried out samples from 685 who were admitted CAP 108 non‐CAP control patients. Atypical detected using Pneumoslide IgM test Vircell, Spain. All patients divided into 6 groups according to age: 18‐24, 25‐44, 45‐59, 60‐74, 75‐89, >90. Results The total positive...

10.1002/jcla.23419 article EN cc-by Journal of Clinical Laboratory Analysis 2020-06-14

Abstract Background and purpose : Whether symptomatic unruptured intracranial aneurysms (UIAs) lead to change in circulating inflammation remains unclear. This study aims evaluate the role of hematological inflammatory indicators predicting UIA. Methods Adult patients diagnosed with saccular aneurysm from March 2019 August 2022 were recruited retrospectively. Clinical laboratory data, including white blood cells (WBC), neutral counts (NEUT), lymphocyte (LYM), monocyte (MONO) each patient,...

10.21203/rs.3.rs-3281066/v1 preprint EN cc-by Research Square (Research Square) 2023-08-25
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