A5046773256- Dermatology and Skin Diseases
- Diamond and Carbon-based Materials Research
- Advanced ceramic materials synthesis
- melanin and skin pigmentation
- Mast cells and histamine
- Extracellular vesicles in disease
- Advanced materials and composites
- Atherosclerosis and Cardiovascular Diseases
- Skin and Cellular Biology Research
- Allergic Rhinitis and Sensitization
- Advancements in Battery Materials
- Systemic Sclerosis and Related Diseases
- Adipose Tissue and Metabolism
- Image Enhancement Techniques
- Reproductive System and Pregnancy
- Liver Disease Diagnosis and Treatment
- Advanced Vision and Imaging
- Computer Graphics and Visualization Techniques
- Exercise and Physiological Responses
- Food Allergy and Anaphylaxis Research
- Mitochondrial Function and Pathology
- Graphene research and applications
- Advanced battery technologies research
- Supercapacitor Materials and Fabrication
- Skin Protection and Aging
Huazhong University of Science and Technology
2021-2025
Tongji Hospital
2021-2025
Zhejiang Sci-Tech University
2023
Shaanxi University of Science and Technology
2020-2021
Fibroblasts are an important subset of mesenchymal cells in maintaining skin homeostasis and resisting harmful stimuli. Meanwhile, fibroblasts modulate immune cell function by secreting cytokines, thereby implicating their involvement various dermatological conditions such as psoriasis, vitiligo, atopic dermatitis. Recently, variations the subtypes expression profiles have been identified these prevalent autoimmune diseases, implying that may exhibit distinct functionalities across different...
Melanoma is a highly invasive malignancy with poor prognoses in advanced stages. Developing risk model that can accurately assess prognosis and guide personalized treatment crucial for improving the clinical management of melanoma. This study aims to develop validate an immune-based prognostic melanoma through comprehensive bioinformatics analysis. We collected transcriptomic data from multiple public databases identified 9 immune features significantly associated using single-sample Gene...
Exosomes, bilaterally phospholipid-coated small vesicles, are produced and released by nearly all cells, which comprise diverse biological macromolecules, including proteins, DNA, RNA, others, that participate in the regulation of their functions. An increasing number studies have revealed contents exosomes, particularly microRNA(miRNA), play a significant role pathogenesis various diseases, autoimmune skin diseases. MiRNA is class single-stranded non-coding RNA molecules possess...
Rationale: Nonalcoholic fatty liver disease (NAFLD) is a kind of metabolic characterized by steatosis. Excessive reactive oxygen species (ROS) originating from dysfunctional mitochondria the major pathophysiological contributor in development NAFLD and thought to be promising therapeutic target. A few reports demonstrate antioxidative treatments for NAFLD. Methods: Male C57 mice were fed on normal chow diet (ND) or high-fat (HFD) 8 weeks. PBS N-acetyl cysteine (NAC) was gavaged mice. LO2...
Vitiligo is a common autoimmune skin disease caused by autoreactive CD8+ T cells. The diverse effects of 1,25-dihydroxyvitamin D₃ [1,25(OH)₂D₃] on immune cell metabolism and proliferation have made it an interesting candidate as supporting therapeutic option in various diseases. This study aimed to elucidate the immunomodulatory 1,25(OH)₂D₃ vitiligo. Cross-sectional relationships between serum levels characteristics were investigated 327 patients with then vivo vitro, respectively. We found...
Objectives Atopic dermatitis (AD) can be classified into intrinsic AD(IAD) and extrinsic AD(EAD). However, the differences in clinical features pathogenesis between these two subtypes of AD are currently unclear. This study aimed to analyse peripheral blood biomarkers Chinese patients with severe IAD EAD order elucidate physiopathogenesis AD.
Atopic dermatitis (AD) is a chronic inflammatory skin condition with complex causes involving immune factors. The presence of essential trace elements that support system function can influence the development this condition. This study investigated how serum impact pathogenesis atopic dermatitis. Upon analyzing microelements in AD patients and control subjects, it was observed had notably lower zinc levels. Genomic analysis revealed distinct gene expression patterns, specifically increased...
Abstract Learning-based approaches have made substantial progress in capturing spatially-varying bidirectional reflectance distribution functions (SVBRDFs) from a single image with unknown lighting and geometry. However, most existing networks only consider per-pixel losses which limit their capability to recover local features such as smooth glossy regions. A few generative adversarial use multiple discriminators for different parameter maps, increasing network complexity. We present novel...
BackgroundPlasma exosomal microRNAs (miRNAs) have been used as potential biomarkers for various diseases and investigated their possible involvement in the pathogenesis of vitiligo. However, miRNA expression profile plasma exosomes patients with non-segmental vitiligo (NSV) has not determined yet.ObjectiveTo screen differentially expressed derived from NSV explore roles NSV.MethodsHigh-throughput sequencing was performed to determine profiles miRNAs NSV. The effect upregulated miR-1469...
<title>Abstract</title> Background Growing evidence shows a significant association between vitiligo and several allergic diseases. However, the real causality remains unclear considering susceptibility of epidemiological studies to residual confounders. Methods We conducted bidirectional two-sample Mendelian randomization (MR) analysis investigate relationship seven common diseases including atopic dermatitis (AD), rhinitis, contact dermatitis, conjunctivitis, purpura, asthma urticaria by...