A5115602103- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Quantum Chromodynamics and Particle Interactions
- Particle Detector Development and Performance
- Dark Matter and Cosmic Phenomena
- Cosmology and Gravitation Theories
- Neutrino Physics Research
- Computational Physics and Python Applications
- Astrophysics and Cosmic Phenomena
- Black Holes and Theoretical Physics
- Cancer Immunotherapy and Biomarkers
- Radiation Detection and Scintillator Technologies
- Lung Cancer Research Studies
- Nuclear reactor physics and engineering
- Solar and Space Plasma Dynamics
- Particle Accelerators and Free-Electron Lasers
- Natural Language Processing Techniques
- Cancer, Hypoxia, and Metabolism
- Topic Modeling
- CO2 Reduction Techniques and Catalysts
- Medical Imaging Techniques and Applications
- Atomic and Subatomic Physics Research
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
University of Science and Technology of China
2012-2025
Lanzhou University
2021-2025
Peking University
1998-2025
Hefei Institutes of Physical Science
2024-2025
Tongji University
2006-2025
Rutgers, The State University of New Jersey
2005-2025
Nanjing Normal University
2024-2025
Rutgers New Jersey Medical School
2025
Rutgers Sexual and Reproductive Health and Rights
2005-2025
Shandong University
2006-2025
Objectives. This research assessed how parents' transfers of sentiment, time, and financial assets to their adolescent/young adult children affect the children's propensity in middle age provide social support aging parents. We tested whether mechanism long-term intergenerational exchange is better modeled as a return on investment, an insurance policy triggered by longevity or physical frailty parents, result altruistic (or other nonreciprocal) motivations part children. Methods. Models...
The measurement of the energy spectrum cosmic ray helium nuclei from 70 GeV to 80 TeV using 4.5 years data recorded by Dark Matter Particle Explorer (DAMPE) is reported in this work. A hardening observed at an about 1.3 TeV, similar previous observations. In addition, a spectral softening 34 revealed for first time with large statistics and well controlled systematic uncertainties, overall significance 4.3σ. DAMPE measurements both protons suggest particle charge dependent energy, although...
Abstract Proton exchange membrane (PEM) water electrolysis holds great promise in revolutionizing clean energy production by enabling the efficient generation of hydrogen. Nevertheless, a formidable challenge persists realm designing electrocatalysts that are both highly active and acid‐resistant during oxygen evolution reaction (OER), thereby mitigating substantial kinetic barrier. In this study, facile synthesis iridium‐yttrium (IrY) alloy nanocatalysts via thermal shock method is...
Fibroblasts undergo a morphological transformation to reactive phenotype in the tumor microenvironment characterized by expression of proteins such as fibroblast activation protein (FAP), post-prolyl endopeptidase with largely restricted carcinoma-associated fibroblasts. Thapsigargin (TG) is highly toxic natural plant product that triggers rise intracellular calcium levels and apoptosis. FAP therefore provocative target for prodrugs consisting FAP-specific peptide coupled potent cytotoxic...
Large language models (LLMs) have significantly advanced the field of natural processing (NLP), providing a highly useful, task-agnostic foundation for wide range applications. However, directly applying LLMs to solve sophisticated problems in specific domains meets many hurdles, caused by heterogeneity domain data, sophistication knowledge, uniqueness objectives, and diversity constraints (e.g., various social norms, cultural conformity, religious beliefs, ethical standards applications)....
Large Language Models (LLMs), renowned for their superior proficiency in language comprehension and generation, stimulate a vibrant ecosystem of applications around them. However, extensive assimilation into various services introduces significant security risks. This study deconstructs the complexities implications prompt injection attacks on actual LLM-integrated applications. Initially, we conduct an exploratory analysis ten commercial applications, highlighting constraints current attack...
The purpose of this study was to investigate seasonal variations in population monthly hemoglobin A1c (A1c) values over 2 years (from October 1998 September 2000) among US diabetic veterans. cohort included 285,705 veterans with 856,181 tests. authors calculated the average for overall and subpopulations defined by age, sex, race, insulin use, climate regions. were higher winter lower summer a difference 0.22. proportion greater than 9.0% followed similar pattern that varied from 17.3%...
Pre-training, which utilizes extensive and varied datasets, is a critical factor in the success of Large Language Models (LLMs) across numerous applications. However, detailed makeup these datasets often not disclosed, leading to concerns about data security potential misuse. This particularly relevant when copyrighted material, still under legal protection, used inappropriately, either intentionally or unintentionally, infringing on rights authors. In this paper, we introduce framework...
The utility of single-chain Fv proteins as therapeutic agents would be realized if the circulating lives these minimal antigen-binding polypeptides could both prolonged and adjustable. We have developed a general strategy for creating tailored monoPEGylated antibodies. Free cysteine residues were engineered in an anti-TNF-alpha scFv at C-terminus or within linker segments orientations, V(L)-linker-V(H) V(H)-linker-V(L). High-level expression 10 designed variant Pichia pastoris allowed rapid...
Journal Article Bayesian analysis of matrix normal graphical models Get access Hao Wang, Wang Department Statistical Science, Duke University, Durham, North Carolina 27708, U.S.A.hao@stat.duke.edumike@stat.duke.edu Search for other works by this author on: Oxford Academic Google Scholar Mike West Biometrika, Volume 96, Issue 4, December 2009, Pages 821–834, https://doi.org/10.1093/biomet/asp049 Published: 09 October 2009 history Received: 01 February 2008 Revision received:
Abstract Highly luminescent carbon dots (CDs) have garnered significant attention and are increasingly utilized in various fields. Despite its importance, there has been a lack of comprehensive reviews focusing specifically on highly CDs. It is aimed here to fill that gap by exploring CDs with high photoluminescence quantum yield (PLQY), starting an examination the mechanisms underlying The selection synthetic raw materials preparation methods along research progress reviewed information...
Abstract. Lack of reliable long-term precipitation record from the northern Tibetan Plateau has constrained our understanding variations in this region. We drilled an ice core on Puruogangri Ice Field central 2000 to reveal variations. The well dated part extends back AD 1600, allowing us construct a 400-year annual accumulation record. This shows that plateau experienced drier period with average ~300 mm 19th century, compared ~450 wetter periods during 1700–1780 and 20th century. pattern...
Studies of the nature inhibitory action inorganic phosphate, fluoride, and some detergents on 5′-adenylic acid deaminase activities rat brain liver show that as well ATP, is an effector deaminase. Inorganic phosphate was found to be a competitive inhibitor in absence but presence inhibition uncompetitive. ATP strongly prevented by phosphate. It appears competes with substrate, AMP, activator, simultaneously at active site site, respectively. Fluoride inhibited noncompetitively uncompetitive...
Vitamin D (VD) possesses immunomodulatory properties, but its role in chronic rhinosinusitis with nasal polyps (CRSwNP) remains poorly studied. Herein, we aim to explore the regulation and function of VD3 CRSwNP.
The non-invasive detection of Helicobacter pylori (H. pylori) and its resistance to clarithromycin levofloxacin significantly improves the management infected patients by enabling tailored eradication treatments without need for endoscopic procedures. This study aimed assess effectiveness real-time PCR (RT-PCR) assays in identifying H. infection antibiotic stool gastric biopsy specimens.
Modulating the inflammatory microenvironment to reconstruct fibrocartilaginous layer while promoting tendon repair is crucial for enhancing tendon-to-bone healing in rotator cuff (RCR), a persistent challenge orthopedics. Small extracellular vesicles (sEVs) hold significant potential modulate inflammation, yet efficient production of highly bioactive sEVs remains substantial barrier their clinical application. Moreover, achieving minimally invasive local delivery interface presents technical...