A5101886774- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Gout, Hyperuricemia, Uric Acid
- Birth, Development, and Health
- Sodium Intake and Health
- Liver Disease Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Obesity, Physical Activity, Diet
- Cardiovascular Disease and Adiposity
- Hormonal Regulation and Hypertension
- Heart Rate Variability and Autonomic Control
- Antenna Design and Analysis
- Antenna Design and Optimization
- Diet and metabolism studies
- Sphingolipid Metabolism and Signaling
- Microbial metabolism and enzyme function
- Nutritional Studies and Diet
- Parathyroid Disorders and Treatments
- Alcohol Consumption and Health Effects
- Biomarkers in Disease Mechanisms
- Advanced Power Amplifier Design
- COVID-19 and Mental Health
- Nutrition, Health and Food Behavior
Peking University
2025
Peking University International Hospital
2025
California Department of Public Health
2025
First Affiliated Hospital of Xi'an Jiaotong University
2015-2024
Tongji Hospital
2015-2024
Ningbo University
2024
Harbin Engineering University
2024
Zhejiang University
2024
Huazhong University of Science and Technology
2024
The First Hospital of Changsha
2024
Abstract Background The triglyceride-glucose index (TyG index) has emerged as a reliable surrogate marker of insulin resistance associated with arterial stiffness. However, most studies were based on cross-sectional design, and few have evaluated the longitudinal impact TyG This study aimed to investigate associations single time point measurement long-term trajectory stiffness in Chinese cohort. Methods Data are derived from Hanzhong Adolescent Hypertension Cohort study. A total 2480...
In this correspondence paper, an unmanned aerial vehicle (UAV) enabled mobile-edge computing (MEC) server is considered to provide MEC services for multiple ground users by employing a time-division access protocol. Our objective solve the joint optimization problem of UAV position, time slot allocation, and computation task partition, which minimizes system energy consumption all while ensuring successful during block. We propose globally optimal solution, found two-dimensional search over...
Background Although high BP is one of the most important factors affecting renal function, whether longitudinal trajectories in early life course are associated with function damage later unclear. Methods To investigate correlation between from childhood to adulthood and middle age, we used group-based trajectory models identify 2430 individuals (aged 6–15 years old at baseline) participating ongoing Hanzhong Adolescent Hypertension Cohort. We tested association these subclinical adjusting...
Vitamin D (VD) possesses immunomodulatory properties, but its role in chronic rhinosinusitis with nasal polyps (CRSwNP) remains poorly studied. Herein, we aim to explore the regulation and function of VD3 CRSwNP.
Objectives. To characterize the intersection of social determinants health, measured as availability community opportunities for healthy living, and sexually transmitted infections (STIs) in California. Methods. Geocoded 2013-2021 California bacterial STI cases were aggregated into Healthy Places Index (HPI) quartiles. Communities lowest scoring HPI quartile have fewest while communities highest most opportunities. Results. As became more available, risk decreased. Asian people had rates,...
In recent years, severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infection has been prevalent worldwide. Pregnant women belong to a special group, and it is very important for clinicians pay attention the impact of SARS-CoV-2 on pregnancy outcomes. However, there are limited studies outcomes during first trimester. To investigate effect in trimester Clinical information pregnant whose last menstrual period was between October 1, 2022, April 2023, who were registered Obstetrics...
Abstract Uric acid (UA) has been proposed as an important risk factor for cardiovascular and renal morbidity. We conducted interventional trial to assess effects of altered salt intake on plasma urine UA levels the relationship between sensitivity in humans. Ninety subjects (18–65 years old) were sequentially maintained a normal diet 3 days at baseline, low-salt 7 (3.0 g/day, NaCl), high-salt additional (18.0 g/day NaCl). Plasma significantly increased from baseline decreased diet. By...
Previous studies have confirmed that exposure to particulate matter with a diameter of ≤2.5 µm (PM2.5) is associated inflammation. PM2.5 decreases cardiac cell viability and increases apoptosis through overproduction reactive oxygen species (ROS). In the present study, role in ECs was investigated vitro. Human umbilical vein endothelial cells human microvascular (ECs) were incubated (100‑800 µg/ml) investigate effects on EC viability, migration, tube formation intracellular levels ROS. Cell...
Abstract High uric acid (UA) level and high salt intake are reportedly associated with cardiovascular disease. This study investigated the association between UA urinary sodium excretion, as well its interaction on risk of prehypertension. A total 1869 participants without hypertension were recruited from a previously established cohort in Shaanxi Province, China. The classified normotensive or prehypertensive basis their blood pressure. Increasing quartiles excretion UA/creatinine levels...
Objective: Atherosclerotic diseases are the leading cause of death worldwide. This study aimed to investigate predictors brachial–ankle pulse wave velocity (baPWV) and carotid intima–media thickness (CIMT) progression in a Chinese cohort over 12-year follow-up period determine whether these differ by time. Methods: A total 202 participants were recruited from previously established Shaanxi Province, China. Both baPWV CIMT measured 2013 2017. Multivariable regression was used progression....
Obesity and hypertension play important roles in the development of arterial stiffness. We aimed to examine sex differences impact cumulative long-term burden trends body mass index (BMI) blood pressure (BP) since childhood on adult stiffness (AS).This longitudinal study consisted 1553 individuals aged 6-15 years, who were examined 4 or more times for BMI BP childhood, with a follow-up period 30 years. The area under curve (AUC) was calculated as measure (total AUC) (incremental from...
Burn injury is a growing medical problem associated with public health, and few effective agents are available for treatment of this disease. In the present study, burn rat model was developed accelerated effect Aloe vera fermentation on healing evaluated. Our results indicated that could markedly reduce DPPH (56.12%), O2·- (93.5%), ·OH (76.12%), Fe2+ chelation (82%), oxygen-reduction activity (0.28 μg/ml) significantly inhibited growth pathogens S. typhimurium ATCC 13311 (inhibition zone...
Background: Whether segmentectomy is appropriate for stage IA non-small cell lung cancer (NSCLC), especially NSCLC with a tumor size of 2–3 cm, remains controversial. Thus, we conducted this meta-analysis to compare and lobectomy cm ≤2 NSCLC. Methods: A systematic screening online databases (PubMed, Embase, Web Science, Cochrane Library) was regarding the terms perioperative outcomes, overall survival (OS), recurrence-free (RFS), disease-free (DFS). The inverse-variance Mantel-Haenszel...
Xuebijing (XBJ) injection is a complex traditional Chinese prescription that has been widely used to treat sepsis in China. However, its underlying mechanisms on still remain uninvestigated. In this study, 150 male Sprague Dawley rats were randomly divided into normal control group, cecal ligation and puncture (CLP) CLP+XBJ CLP+gibberellic acid group. Each of them contained 3 subgroups different treatment periods (12, 24, 48 hours after injection, respectively). The mRNA expression HMGB1...
Abstract Background Metabolically healthy obesity (MHO) has been reported to be associated with the development of vascular damage by carotid intima-media thickness, but relationship between metabolic health and phenotypes arterial stiffness is still unknown. Our hypothesized that different might stiffness, subjects in MHO phenotype not have increased risks compared those metabolically nonobesity (MHNO), while unhealthy individuals stiffness. Methods A prospective cohort 2076 participants...
Objective: Pregnancy-associated plasma protein-A2 (PAPP-A2) is the homolog of PAPP-A in vertebrate genome and its role protecting against salt-induced hypertension salt-sensitive rats has been confirmed. We sought to examine associations PAPP-A2 levels genetic variants with salt sensitivity, blood pressure (BP) changes incidence humans. Methods: Eighty participants (18–65 years old) sequentially consuming a usual diet, 7-day low-salt diet (3.0 g/day) high-salt (18 g/day). In addition, we...
Background and objectives The aim of the study was to examine associations uric acid (UA) in blood urine with subclinical renal damage (SRD) its progression a Chinese cohort. Methods 1) 2342 participants from our previously established cohort who were followed up 2017 included. Cross-sectional analysis used relationships between serum urinary UA risk SRD. 2) A total 266 recruited same 2013, 2017. Longitudinal determine SRD, which defined as albumin-to-creatinine ratio (uACR) or estimated...
Objective: Cyclooxygenase (COX)-2, an inducible isoform of the major rate-limiting enzymes that regulate production prostaglandins is associated with injury, inflammation and proliferation. We sought to examine whether plasma COX-2 levels its genetic variants salt sensitivity, BP changes and/or hypertension in humans. Methods: Eighty participants (aged 18–65 years) were maintained sequentially either on a usual diet for 3 days, low-salt (3.0 g) 7 high-salt (18.0 additional days. In addition,...