A5010618567- S100 Proteins and Annexins
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Neuroscience and Neural Engineering
- Advanced Sensor and Energy Harvesting Materials
- Glioma Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Tactile and Sensory Interactions
- Nanoplatforms for cancer theranostics
- Neurological Disorders and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Inflammation biomarkers and pathways
- Planarian Biology and Electrostimulation
- Gas Sensing Nanomaterials and Sensors
- Drug Transport and Resistance Mechanisms
- Neurological disorders and treatments
- Muscle activation and electromyography studies
Ningbo University
2024
Harbin Medical University
2022-2024
First Affiliated Hospital of Harbin Medical University
2022-2024
Abstract Ischemic stroke is a refractory disease that endangers human health and safety owing to cerebral ischemia. Brain ischemia induces series of inflammatory reactions. Neutrophils migrate from the circulatory system site accumulate in large numbers at inflammation across blood–brain barrier. Therefore, hitchhiking on neutrophils deliver drugs ischemic brain sites could be an optimal strategy. Since surface has formyl peptide receptor (FPR), this work modifies nanoplatform by...
Abstract Traumatic brain injuries (TBI) and stroke are major causes of morbidity mortality in both developing developed countries. The complex heterogeneous pathophysiology TBI cerebral ischemia‐reperfusion injury (CIRI), addition to the blood‐brain barrier (BBB) resistance, is a advancement diagnostics therapeutics. Clinical data showed that severity positively correlated with number neutrophils peripheral blood sites. Furthermore, neutrophil extracellular traps (NETs) released by correlate...
Abstract Stress tolerance plays a vital role in ensuring the effectiveness of piezoresistive sensing films used flexible pressure sensors. However, existing methods for enhancing stress employ dome-shaped, wrinkle-shaped, and pyramidal-shaped microstructures intricate molding demolding processes, which introduce significant fabrication challenges limit performance. To address these shortcomings, this paper presents periodic microslits film made multiwalled carbon nanotubes...
Abstract Traumatic brain injury (TBI) is the main cause of death and disability in people all ages worldwide. Neuroinflammation plays beneficial harmful roles secondary injury. Neutrophils play an important role chemically mediated inflammatory responses through myeloperoxidase (MPO) inflammation triggered by TBI. Herein, a nanodrug targeting neutrophils MPO chemical biological functions after TBI designed to enhance retention sustained release drug cargos for improved therapy....
To investigate the impact of electrode structure on Electrical Stimulation Therapy (EST) for chronic wound healing, this study designed three variants flexible microelectrodes (FMs) with Ag-Cu coverings (ACCs), each exhibiting distinct geometrical configurations: hexagonal, cross-shaped, and serpentine. These were integrated PPY@PDA/PANI (3/6) hydrogel dressings. Comprehensive animal studies, coupled detailed electrical mechanical modeling simulations, conducted to assess their performance....
To investigate the impact of electrode structure on Electrical Stimulation Therapy (EST) for chronic wound healing, this study designed three variants flexible microelectrodes (FMs) with Ag-Cu coverings (ACCs), each exhibiting distinct geometrical configurations: hexagonal, cross-shaped, and serpentine. These were integrated PPY/PDA/PANI (3/6) (full name: polypyrrole/polydopamine/polyaniline 3/6). Hydrogel dressing comprehensive animal studies, coupled detailed electrical mechanical modeling...
Hesperetin Nanoparticles In article number 2205787, Xiangtong Zhang, Liao Cui, Chunming Huang, Longguang Tang, and co-workers design a hesperetin nanoparticle that targets neutrophils, T-Hes, catalyzed by myeloperoxidase secreted which can effectively identify inflammatory neutrophils quickly gather in the injured area after traumatic brain injury. The sustained release of T-Hes shows great advantages anti-inflammatory treatment, reducing edema improving neurological function.