A5053207071- Advanced MRI Techniques and Applications
- Medical Imaging Techniques and Applications
- Alzheimer's disease research and treatments
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Technology and Human Factors in Education and Health
- Cardiac Imaging and Diagnostics
- MRI in cancer diagnosis
- Dementia and Cognitive Impairment Research
- Medical Imaging and Pathology Studies
- Spine and Intervertebral Disc Pathology
- Advanced X-ray and CT Imaging
- Sarcoidosis and Beryllium Toxicity Research
- Healthcare Systems and Public Health
- Prostate Cancer Diagnosis and Treatment
- Biomedical and Engineering Education
- Parkinson's Disease Mechanisms and Treatments
- Lanthanide and Transition Metal Complexes
- Neurological and metabolic disorders
- Prostate Cancer Treatment and Research
- Medical Imaging and Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- AI in cancer detection
- Musculoskeletal pain and rehabilitation
- Neurobiology of Language and Bilingualism
Mayo Clinic
2024-2025
Mayo Clinic in Arizona
2024-2025
University of Michigan
2022-2025
Moscow Engineering Physics Institute
2015
Transactive response DNA-binding protein 43 kDa (TDP-43) deposition is linked to regional brain atrophy in Alzheimer's disease (AD), but diffusion changes associated with AD-related TDP-43 proteinopathy remain underexplored. This study evaluates the potential of tensor imaging (DTI) and neurite orientation dispersion density (NODDI) as vivo markers for detecting AD. We analyzed DTI NODDI metrics 49 cases AD neuropathologic changes, categorized by postmortem status. Diffusion from temporal...
Abstract The purpose of this study was to assess the quality clinical brain imaging in healthy subjects and patients on an FDA‐approved commercial 0.55 T MRI scanner, provide information about feasibility using scanner a workflow. In IRB‐approved study, examinations were prospectively performed 10 (February–April 2022) retrospectively derived from 44 (February–July 2022). Images collected following pulse sequences available for assessment: axial DWI (diffusion‐weighted imaging), apparent...
We aimed to compare arterial spin labeling (ASL) with dynamic susceptibility contrast (DSC) enhanced perfusion MRI for the surveillance of primary and metastatic brain tumors at 3T, both in terms lesion metrics diagnostic accuracy.In this retrospective study, we included 115 patients, who underwent ASL DSC same 3T scanning session between 1 January 31 December 2019. ASL-derived cerebral blood flow (CBF) maps DSC-derived relative volume (rCBV) maps, uncorrected corrected leakage, were created...
Abstract INTRODUCTION Primary age‐related tauopathy (PART) is characterized by neurofibrillary tangles and minimal β‐amyloid deposition, diagnosed postmortem. This study investigates 18 F‐flortaucipir (FTP) PET imaging for antemortem PART diagnosis. METHODS We analyzed FTP scans from 50 autopsy‐confirmed 13 control subjects. Temporal lobe uptake was assessed both qualitatively quantitatively. Demographic clinicopathological characteristics voxel‐level using SPM12 were compared between...
The purpose of this study is to assess the feasibility use MR Fingerprinting combined with ADC mapping for characterizing prostate transition zone (TZ) cancers. This quantitative approach has shown promising results in differentiating cancer from normal tissue peripheral and zones, separating low intermediate/high grade tumors PZ. Our aimed confirm previous observations differences T1, T2 between cancers appearing TZ, utility MRF-derived T1 distinguishing lesions high/intermediate-grade TZ.
This study aims to compare the image quality of clinical brain imaging on an FDA-approved commercial low-field 0.55T MRI scanner and conventional higher field 1.5/3T systems. The 205 compatible series in 30 patients acquired at 1.5T/3T systems was rated by two neuroradiologists. Despite significant differences ratings between low- higher-field scanners, all sequences performed received indicating that they were acceptable for diagnostic use. work indicates system can be used routine practice.
The purpose of this study is to assess the quality brain imaging studies performed on an FDA-approved commercial 0.55T MRI system, and provide information about feasibility using scanner in a clinical workflow. image 1356 series (378 healthy subjects, 978 patients) was independently rated by two neuroradiologists. While images from T1w SPACE, DWI/ADC, FLAIR, SWI, T2w TSE sequences received acceptable scores, contrast-enhanced sequence lower, although acceptable, average scores. Our results...
Motivation: TDP-43, a 43kDa protein in the brain, plays crucial role neurodegenerative disorders and is potential target for clinical trials. Confirmation currently requires an autopsy. Goal(s): To explore antemortem biomarkers early-stage TDP-43 detection using conventional MRI 18F-FDG-PET scans. Approach: Blinded visual evaluations of scans were performed utilizing specialized rating scales. Results: TDP-43(+) cases exhibited more medial temporal atrophy on MRI, though influenced by age....
The purpose of this study was to determine which sequences can be immediately deployed for brain and spine imaging on a low-field 0.55T MRI system, with the goal generating optimized protocols used at other sites routine clinical neuroimaging. image quality 174 images rated by two neuroradiologists. Almost all (T1w, T2w, FLAIR, DWI, MRA) DIXON) received scores corresponding acceptable diagnostic quality. These form numerous neurological protocols, based these results could collected 0.55T.