A5100341941- HER2/EGFR in Cancer Research
- Advanced Breast Cancer Therapies
- Mobile Health and mHealth Applications
- Breast Cancer Treatment Studies
- Toxin Mechanisms and Immunotoxins
- Physical Activity and Health
- Endometrial and Cervical Cancer Treatments
- Obesity, Physical Activity, Diet
- Cancer Treatment and Pharmacology
- Advanced Neural Network Applications
- Polysaccharides and Plant Cell Walls
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Epigenetics and DNA Methylation
- ATP Synthase and ATPases Research
- Software Reliability and Analysis Research
- Polydiacetylene-based materials and applications
- Synthesis and Properties of Aromatic Compounds
- Herbal Medicine Research Studies
- Transgenic Plants and Applications
- Software Engineering Research
- Advanced oxidation water treatment
- Evaluation Methods in Various Fields
- Cervical Cancer and HPV Research
- Environmental remediation with nanomaterials
- Diverse Academic Research Analysis
Sun Yat-sen Memorial Hospital
2024-2025
Sun Yat-sen University
2024-2025
Fujian University of Technology
2025
Zhejiang Marine Fisheries Research Institute
2022-2024
Xijing Hospital
2023-2024
Air Force Medical University
2023-2024
Zhejiang University
2022-2023
Changzhi Medical College
2022
Universidade Federal de Uberlândia
2021
Wuhan University of Technology
2021
Abstract Objective Lymph node metastasis (LNM) critically impacts the prognosis and treatment decisions of cervical cancer patients. The accuracy sensitivity current imaging techniques, such as CT MRI, are limited in assessing lymph status. This study aims to develop a more accurate efficient method for predicting LNM. Methods Three independent cohorts were merged divided into training internal validation groups, with our cohort those from other centers serving external validation. A...
The convolution neural networks (CNNs) are widely used in computer vision applications nowadays. However, the trends of higher accuracy and resolution generate larger networks, indicating that computation I/O bandwidth key bottlenecks to reach performance. Xilinx's latest 7nm Versal ACAP platform with AI-Engine (AIE) cores can deliver up-to 8x silicon compute density at 50% power consumption compared traditional FPGA solutions. In this paper, we propose XVDPU: AIE-based int8-precision CNN...
Background HER2-positive molecular breast cancer subtypes are characterized by high aggressiveness and malignancy, their metastasis mortality rates among the highest of all types cancer. The use anti-HER2-targeted agents in neoadjuvant therapy has significantly improved prognosis patients with In this study, we investigated efficacy safety a Chinese THP regimen (docetaxel, trastuzumab biosimilar TQB211 plus pertuzumab TQB2440 or pertuzumab) for ER/PR-negative China. Method All enrolled...
Today, convolutional neural networks (CNNs) are widely used in computer vision applications. However, the trends of higher accuracy and resolution generate larger networks. The requirements computation or I/O key bottlenecks. In this article, we propose XVDPU: AI Engine (AIE)-based CNN accelerator on Versal chips to meet heavy requirements. To resolve IO bottleneck, adopt several techniques improve data reuse reduce An arithmetic logic unit is further proposed that can better balance...
Abstract Background In intensive care units (ICU), mechanical ventilation (MV) is commonly applied to save patients’ lives. However, ventilator-induced diaphragm dysfunction (VIDD) can complicate treatment by hindering weaning in critically ill patients and worsening outcomes. The goal of this study was identify potential genes involved the endogenous protective mechanism against VIDD. Methods Twelve adult male rabbits were assigned either an MV group or a control under same anesthetic...
Luspatercept reduced the severity of anemia in transfusion-dependent lower risk MDS with ring sideroblasts (RS) MEDALIST trial. Here we present real-world data a prospective multicenter registry study patients treated luspatercept (ChiCTR2300071857). Patients who were not enrolled trial also evaluated, including those higher IPSS-R risk, without sideroblasts, or failed to prior hypomethylating agent (HMA) therapy. Eligible ≥ 18 years old and RBC (defined as ≥2 units transfusion per 8 weeks)....
e12635 Background: Chemotherapy combined with dual anti-HER2 target therapy has become the standard neoadjuvant regimen for HER2+ breast cancer. Patients achieving pCR have a relatively better prognosis. Inetetamab (Septin) is an innovative HER2 monoclonal antibody drug developed in China. It been proven to delay progression of metastatic cancer patients and bring survival benefits. The purpose this study was explore efficacy safety Inetetamab, Pyrotinib Albumin-bound Paclitaxel treatment...
Objectives: To describe treatment patterns and prognoses for clear cell adenocarcinoma of the cervix (CCAC), a poorly understood rare tumor. Methods: A retrospective case‒control study was conducted using Surveillance, Epidemiology, End Results (SEER) database, focusing on females diagnosed with CCAC between 2000 2019. Kaplan‒Meier analysis, propensity score matching, Cox regression subgroup analysis were used to assess outcomes risk factors. Results: Of 52,153 patients cervical cancer in...
Abstract This comprehensive review critically assesses tailored management strategies for clear cell carcinoma of the cervix (cCCC), an uncommon subtype cervical adenocarcinomas. A globally prevalent condition, cCCC affects individuals across diverse racial and ethnic groups. Notably, a significant risk factor associated with is intrauterine exposure to diethylstilbestrol (DES), synthetic estrogen historically prescribed address pregnancy-related complications. Intriguingly, almost...
Abstract Background: Despite that dual anti-HER2 therapy (Trastuzumab and Pertuzumab, TP) is one of the commonly used regimens for neoadjuvant treatment HER2-positive breast cancer, previous studies showed its pCR rate rarely exceeds 63%. Additionally, it associated with higher risk cardiac adverse events. TQB2440, a biosimilar pertuzumab, strong affinity specificity, can effectively bind HER2 epitope. In PDX mouse model, TQB2440 promising biological activity minimal cardiotoxicity. this...
A Weight Management Program (WMP) is a critical and promising approach to losing excess weight maintaining healthy lifestyle for obese/overweight people. This study used the RE-AIM framework retrospectively evaluate WeChat-based workplace WMP that include low- high-intensity interventions - self-management (SM) intensive support (IS) designed employees with varying levels of health risk at Chinese company. Both incorporated variety m-health technologies behavioral strategies. While IS group...
The large-scale cultivation of S. fusiforme was hypothesized to effectively improve water quality and environmental characteristics. Specifically, such could promote habitat restoration effects by increasing DO pH levels in addition decreasing nitrogen phosphorus within area waters. Phytoplankton diversity also reflect the health This study explored Sargassum on biodiversity ecosystem a phytoplankton community coastal waters Dongtou island, China. fusiform e increased values but decreased N...
High-performance thermal energy storage technology based on phase change material (PCM) plays an important role in reducing the building consumption and realizing efficient utilization. However, drawbacks such as liquid leakage, poor conductivity, low cycle stability, significantly reduces its service life limits further application. In this paper, a new microencapsulated (MPCM) containing graphite-SiO2 shell eicosane-octadecane (E-O) core was prepared by sol-gel method. A high conductivity...
As the current situation of imperfect model algorithm electrical equipment for energy efficiency evaluation, we set up DEA model. In model, got average load rate, power factor and tri-phase unbalance as inputs indexes. And economic output per unit consumption pollution outputs Then transformed multiple pollutants into a pollutant index through principal component analysis. it desired output. The result 12 industrial enterprises in shows that evaluation is suitable system useful to further...
Weight management program (WMP) is a critical and promising approach for obese/overweight people to lose excess weight maintain healthy lifestyle. The RE-AIM framework was used retrospectively evaluate WeChat-based workplace WMP that included low- high-intensity interventions — self-management (SM) intensive support (IS) designed with varying levels of health risk. Both incorporated variety m-health technologies behavioral strategies. While the IS group additionally received personalized...