A5069267630- Psychedelics and Drug Studies
- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Chemical synthesis and alkaloids
- Food Quality and Safety Studies
- Plant biochemistry and biosynthesis
- Advanced Glycation End Products research
- Advanced Biosensing Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Edible Oils Quality and Analysis
- Biosensors and Analytical Detection
- Protein Hydrolysis and Bioactive Peptides
- Natural Antidiabetic Agents Studies
- Allelopathy and phytotoxic interactions
- Mycotoxins in Agriculture and Food
- Chemical Reaction Mechanisms
- Plant Toxicity and Pharmacological Properties
- Botanical Research and Chemistry
- Indoor Air Quality and Microbial Exposure
- Biochemical and biochemical processes
- Chemical Reactions and Isotopes
- Plant Pathogens and Fungal Diseases
- Biochemical effects in animals
- Spectroscopy and Chemometric Analyses
- Botany and Plant Ecology Studies
Miami University
2019-2024
Stanford University
2022-2023
Ghent University
2006-2012
University of Sfax
2007
Abstract Traditional psychedelics are undergoing a transformation from recreational drugs, to promising pharmaceutical drug candidates with the potential provide an alternative treatment option for individuals struggling mental illness. Sustainable and economic production methods thus needed facilitate enhanced study of these support future clinical efforts. Here, we expand upon current bacterial psilocybin biosynthesis by incorporating cytochrome P450 monooxygenase, PsiH, enable de novo as...
Abstract The development of a liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the simultaneous determination 16 mycotoxins possibly related to ‘Sick Building Syndrome’ on filters and in fungal cultures is described. Fungi‐surface sampling as regards preferably happens by scraping off material vacuuming onto cellulose filters. Therefore, these two media were used samples. They spiked with nivalenol, deoxynivalenol, zearalenone, diacetoxyscirpenol, T‐2 toxin, verrucarol,...
Abstract Enzyme-linked immunosorbent assays (ELISAs) are a cornerstone of modern molecular detection, but the technique still faces notable challenges. One biggest problems is discriminating true signal generated by target molecules versus non-specific background. Here, we developed Si ngle- M olecule C olocalization A ssay (SiMCA) that overcomes this problem employing total internal reflection fluorescence microscopy to quantify proteins based on colocalization fluorescent from orthogonally...
Abstract N ‐methylated tryptamines, such as the hallucinogenic natural products, psilocybin and N,N ‐dimethyltryptamine (DMT), are gaining interest from medical community due to their potential next generation treatments for mental health disorders. The clinical relevance of these compounds has driven scientists develop biosynthetic production routes a number tryptamine drug candidates, efforts ongoing expand further capabilities. To that end, we have characterized substrate preferences two...
A. Adams and D. H. Hey, J. Chem. Soc., 1950, 2092 DOI: 10.1039/JR9500002092
Solid-phase microextraction (SPME) technique is a relatively simple, rapid, inexpensive and solvent-free sampling for the determination of volatiles in plant essential oils when compared to conventional techniques like steam distillation solvent extraction (SDSE). Moreover, newer SPME can be automated does not lead thermal degradation chemical components [1,2]. In order determine best harvest times terms quality chamomile (Matricaria chamomilla L.) grown Belgium, was applied. On April 15,...
Two Gynura species, G. bicolor and divaricata, are used in folk recipes for the treatment of diabetes mellitus south China. Our previous pharmacological study proved that both plants showed significant hypoglycemic activity on normal alloxan-diabetic mice. Sixteen chemical constituents were isolated from CH2Cl2 EtOAc extracts aerial parts bicolor. Their structures determined spectroscopically as hydroxymethylfurfural, benzoic acid, 4-hydroxybenzoic protocatechuic vanillic...
The Maillard reaction, or nonenzymatic browning, includes a complex network of reactions initiated by the condensation reaction carbohydrate and an amino compound, is utmost importance for formation flavour colour in thermally treated foods. Besides volatile compounds, also brown-coloured polycondensation products, named melanoidins, are produced. In latest years, interaction lipid oxidation products classical pathway vice versa particular interest, since it has been shown that course both...
German chamomile (Matricaria chamomilla) is an essential oil bearing plant belonging to Asteraceae family. Reports concerning the effects of nitrogen fertilizer and spacing on content composition are contradictory fragmentary [1–5]. The objective present study was determine influence combined effect grown in Belgium. carried out a loamy sand soil at Ghent University, Belgium, during 2006. experiment laid as Randomized Complete Block (RCB) with split plot design having 3 replications. N level...
German chamomile (Matricaria chamomilla) is an annual plant belonging to Asteraceae family. Since cultivated commercially, the optimum time for sowing has been subject of a number studies [1, 2, 3]. The aim present investigation was determine influence and age seedling on essential oil content composition grown in Belgium. experiment carried out loamy sand soil at Ghent University, Belgium, during 2005. treatments consisted 4 different times planting (15 April, 1, 15 30 May) combination with...
Abstract Gold standard immunoassays depend on specific affinity reagents for accurate molecular quantification. Any cross-reactivity of reagents, wherein the reagent non-specifically binds to unintended molecules, can create false positive binding signals and result in inaccurate quantification analytes. Mitigating represents one greatest challenges diagnostics, remains an unsolved problem. To instead overcome effects cross-reactivity, we present a mathematical framework that uses...
German chamomile (Matricaria chamomilla) is an annual plant belonging to the Asteraceae family. As essential oil yield and components profile during ontogenesis flowering period are variable [1–4], it important that each harvest would target specify compounds. To determine favourable times for obtaining optimum quality of products derived from grown in Belgium, experiment was carried out on a loamy sand soil Ghent University, Belgium. On April 15, 2005, 90 days old seedlings were...