Dan Xu

ORCID: 0009-0002-5131-3691
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About
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Research Areas
  • Cardiovascular Disease and Adiposity
  • Land Use and Ecosystem Services
  • Complement system in diseases
  • Hydrology and Watershed Management Studies
  • Kawasaki Disease and Coronary Complications
  • Inflammation biomarkers and pathways
  • COVID-19 Clinical Research Studies
  • Plant responses to elevated CO2
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Lipid metabolism and disorders
  • Liver Disease Diagnosis and Treatment
  • Coronary Artery Anomalies
  • Metabolomics and Mass Spectrometry Studies
  • Adipokines, Inflammation, and Metabolic Diseases
  • Coastal and Marine Management
  • Medical Research and Treatments
  • Folklore, Mythology, and Literature Studies
  • Climate variability and models
  • Nutrition and Health in Aging
  • Coronary Interventions and Diagnostics
  • Coastal wetland ecosystem dynamics
  • Soil and Land Suitability Analysis
  • Histone Deacetylase Inhibitors Research
  • Climate change impacts on agriculture
  • Plant responses to water stress

Taizhou First People's Hospital
2024

Peking Union Medical College Hospital
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024

First Hospital of Shanxi Medical University
2024

Shanxi Medical University
2024

Qilu Hospital of Shandong University
2024

Children's Hospital of Capital Institute of Pediatrics
2023-2024

Harbin Medical University
2024

First Affiliated Hospital of Harbin Medical University
2024

Wuxi People's Hospital
2023

Background Intranasal transplantation of ANGE-S003 human neural stem cells showed therapeutic effects and were safe in preclinical models Parkinson’s disease (PD). We investigated the safety tolerability this treatment patients with PD whether these would be apparent a clinical trial. Methods This was 12-month, single-centre, open-label, dose-escalation phase 1 study 18 advanced assigned to four-time intranasal 3 doses: 1.5 million, 5 million or 15 evaluate their efficacy. Results 7...

10.1136/jnnp-2023-332921 article EN Journal of Neurology Neurosurgery & Psychiatry 2024-05-09

Climate change is a global scientific problem, and its impact on the spatiotemporal variations of precipitation has been crucial research topic. Although previous studies have used different methods to evaluate characteristics Huaihe River Basin, time series were short few stations could not fully accurately represent characteristics. In this study, daily temperature data collected from 233 meteorological in Basin 1960–2020. The Mann–Kendall test was analyze trend significance interannual...

10.3390/w15010181 article EN Water 2023-01-01

Abstract Background This research aims to investigate the connection between systemic inflammatory response and metabolic syndrome (MetS) across different age groups, with aim of proposing more targeted recommendations. Methods study enrolled 15 959 adults from 2001-2018 National Health Nutrition Examination Survey whom 6739 were diagnosed MetS. After dividing immune-inflammation index (SII) into 4 quartiles, Kruskal–Wallis test weighted chi-square employed assess statistical differences....

10.1210/clinem/dgae669 article EN cc-by The Journal of Clinical Endocrinology & Metabolism 2024-09-25

To explore the association between malnutrition and risk of depression in elderly. Relevant studies were searched PubMed, Web Science, Cochrane Library, Scopus, Embase from establishment database to August 17, 2023. Two researchers independently screened literature, extracted data, evaluated bias included studies. Stata16.0 software was used for meta-analysis. A total 8 observational identified with 11 112 participants, which 2771 elderly patients had depression. The meta-pooled results...

10.5152/alphapsychiatry.2024.231336 article EN ALPHA PSYCHIATRY 2024-05-02

Reasonable quantitative assessment on urban ecosystem health is conducive to the sustainable development of economy and human society. This paper quantitatively evaluated impact land use change services by building a comprehensive evaluation system (vigor–organization–resilience–ecosystem services), then analyzed spatial-temporal pattern, evolution characteristics, driving factors in Shanghai–Hangzhou Bay area (SHB) over 2000–2015 period. The results show that: cropland forest accounted for...

10.3390/land11060867 article EN cc-by Land 2022-06-08

Urban vegetation can deposit dust to reduce pollution, and retention capacity of has become an important indicator for urban ecological construction. We selected five representative in Shanghai explore the regularity deposition on leaves. Due influence leaf area surface characteristics, amount was significantly different each vegetation; Vegetation shows under pollution intensity, before this reaches its limit, it will increase with content environment; Furthermore, water leaves factor...

10.1080/09603123.2020.1714559 article EN International Journal of Environmental Health Research 2020-01-16

Climate change has emerged as a significant man-made global environmental challenge marked by rising temperature. The temperature is supposed to alter climatic patterns like floods and droughts, thereby affecting human life supporting system food production. In order clarify the impact of weather events on agricultural production in karst landforms, this study selected indices growth period crops (start time duration), growing season precipitation, intense number consecutive rainless days,...

10.1155/2019/1401402 article EN cc-by Advances in Meteorology 2019-11-03

The impact of global climate change on the temporal and spatial variations precipitation is significant. In this study, daily temperature data from 258 meteorological stations in Haihe River Basin, for period 1960–2020, were used to determine trend significance changes at interannual interseasonal scales. Mann–Kendall test Spearman’s correlation analysis employed, significant trends correlations determined. At more than 90% selected stations, results showed a increase temperature, both...

10.3390/w13121664 article EN Water 2021-06-15

Purpose More and more patients with community-acquired pneumonia have been detected Chlamydia psittaci ( C. ) infected using metagenomic next-generation sequencing (mNGS). Previously, this was unheard of, several presented severe even required ECMO. We aimed to clarify the clinical characteristics of find out if there are any possible predictors pneumonia. Methods In retrospective study, we included all confirmed cases in Wuxi. Epidemiological, clinical, radiological features, as well...

10.3389/fmed.2023.1150746 article EN cc-by Frontiers in Medicine 2023-08-21

The aim of this study was to determine the frequencies single-nucleotide polymorphisms (SNPs) in Smad3 gene Chinese population and their possible association with chronic obstructive pulmonary disease (COPD). frequency distribution nine SNPs introns determined both COPD patients control groups by TaqMan polymerase chain reaction method using a minor groove binder probe. genotype rs28683050 polymorphism subjects as follows: CC, 67.6%; CT, 27.0% TT, 5.4%; 47.0%; 38.8% 14.2%. Therefore,...

10.1258/ebm.2010.009268 article EN Experimental Biology and Medicine 2010-05-01

Introduction: Limited studies report anxiety and depression prevalence their correlations with prognosis in acute myeloid leukemia (AML). Even worse, risk factors for AML remained unclear. This study aimed to investigate the prevalence, factors, prognostic value of patients. Methods: Totally, 132 de novo patients, 60 non-malignant hematological disease patients (as controls), healthy controls were enrolled. Anxiety status evaluated by Hospital Depression Scale (HADS) all participants....

10.1159/000536457 article EN cc-by-nc Acta Haematologica 2024-02-16

Objective: This study aims to investigate the relationship between thyroid function and prognosis in acute coronary syndrome (ACS) patients after percutaneous intervention (PCI). Methods: According status of at admission, they were divided into euthyroid group (Group A), subclinical hyperthyroidism B), hypothyroidism C), low T3 D). The clinical data four patient groups compared. logistic regression model was used analyze postoperative outcomes with ACS undergoing PCI. Results: A total 200...

10.59958/hsf.7731 article EN The Heart Surgery Forum 2024-09-22

Abstract. Hangzhou Bay is an important estuarial coastal wetland, which offers a large number of land and ecological resources. It plays significant role in the sustainable development resources, environment economy. In this paper, based on remote sensing images 1996, 2005 2013, we extracted wetland data analyzed landscape pattern past 20 years. The results show that: (1) area heading downwards recent decades. Paddy field diminish greatly. (2) single dynamic degree displays that paddy fields...

10.5194/isprs-annals-iv-3-153-2018 article EN cc-by ISPRS annals of the photogrammetry, remote sensing and spatial information sciences 2018-04-23

Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by hemolytic anemia, bone marrow failure, thrombophilia. COVID-19, caused a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with many variants including Omicron. This study collected demographic and clinical data of 20 PNH patients SARS-CoV-2 Omicron infection. They all were high disease activity, LDH level exceeded any documented since the diagnosis PNH, those reported in literature for previously stable treatment...

10.1002/iid3.966 article EN cc-by Immunity Inflammation and Disease 2023-08-01

Assessing personal exposure risk from PM2.5 air pollution poses challenges due to the limited availability of high spatial resolution data for and population density. This study introduced a seasonal spatial-temporal method modeling distribution characteristics at 1-km grid level based on remote sensing Geographic Information Systems (GIS). The high-accuracy density relative model were used assess relationship between public health. results indicated that concentration could be simulated by...

10.3390/ijerph19106154 article EN International Journal of Environmental Research and Public Health 2022-05-18

10.1016/j.jacc.2014.06.492 article EN publisher-specific-oa Journal of the American College of Cardiology 2014-10-01
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