A5100461399- Psoriasis: Treatment and Pathogenesis
- Autoimmune and Inflammatory Disorders Research
- MicroRNA in disease regulation
- Acute Myeloid Leukemia Research
- Inflammasome and immune disorders
- Complement system in diseases
- Aquaculture disease management and microbiota
- Dermatology and Skin Diseases
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Biomarkers in Disease Mechanisms
- Acute Myocardial Infarction Research
- HIV Research and Treatment
- Therapeutic Uses of Natural Elements
- Lipid metabolism and disorders
- Galectins and Cancer Biology
- Aquaculture Nutrition and Growth
- Trace Elements in Health
- Selenium in Biological Systems
- Long-Term Effects of COVID-19
- Circular RNAs in diseases
- Advanced biosensing and bioanalysis techniques
- Animal Diversity and Health Studies
- Immune cells in cancer
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Identification and Quantification in Food
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2023
Guang’anmen Hospital
2020-2023
Shandong Provincial Institute of Dermatology and Venereology
2023
Shandong Provincial Hospital
2023
Shandong First Medical University
2023
Second Hospital of Anhui Medical University
2022
Hebei Medical University
2022
Fourth Hospital of Hebei Medical University
2022
Anhui Medical University
2022
Marine Biology Institute of Shandong Province
2022
To explore the mechanism of sexual transmission human immunodeficiency virus type 1 (HIV-1), we compared HIV-1 gp120 sequences in longitudinal samples from five acute seroconvertors with those their corresponding partners (transmitters). We used a quantitative homoduplex tracking assay to compare overall genetic composition quasispecies each pair and track transmitted viruses during asymptomatic stages infection. In chronically infected transmitters, variants genital secretions differed...
Numerous factors have been claimed to play important roles in colorectal cancer (CRC) tumorigenesis, including myeloid-derived suppressor cells (MDSCs) and other immune cells, cytokines, chemokines; however, the precise mechanisms of tumorigenesis remain elusive, there is a lack effective preventive treatments. Here, we investigated role complement system, key regulator surveillance homeostasis, tumorigenesis. Methods: The prototypical CRC model was induced by combined administration...
Abstract Therapeutic conditions for acute leukemia (AL) mainly rely on diagnosis and detection of minimal residual disease (MRD). However, no serum biomarker has been available clinicians to make AL assessment MRD. In this study, we performed bead fractionation/MALDI‐TOF‐MS analysis sera from patients with AL. Support vector machine algorithm was used obtain diagnostic model that discriminated proteomic spectra controls. Twenty‐six features p <0.00001 had optimal discriminatory...
The aim of the present study was to investigate role and mechanism microRNA-204-5p (miR-204-5p) in atherosclerosis (AS)-related abnormal human vascular smooth muscle cells (hVSMCs) function. Firstly, we analyzed expression miR-204-5p found that level clearly downregulated atherosclerotic plaque tissues blood samples compared normal controls. Then, matrix metallopeptidase-9 (MMP-9) predicted be potential target by TargetScan this prediction confirmed luciferase assays. Besides, observed could...
Interleukin-37, which was discovered in 2000, is a natural suppressor of immune and inflammatory responses. Recent studies reported that IL-37 abnormally expressed several tumor patients, including those with hepatocellular carcinoma, gastric cancer, lung colon epithelial ovarian multiple myeloma. However, the expression potential function leukemia remain unknown.The aim this study to evaluate as prognostic factor its possible mechanism action.Polymerase chain reaction products were analyzed...
Psoriasis is a chronic autoimmune disease. Identification of the biomarkers responsible for Traditional Chinese Medicine (TCM) syndromes psoriasis can help researchers recognize different aspects and find novel therapeutic targets treatment psoriasis. The current study investigated levels circulating Mo-MDSCs Mo-MDSC-associated immune factors in peripheral blood patients with TCM syndromes. We found that frequency (CD14+HLA-DR-/low cells) among CD14+ cells from plaque blood-stasis (BS)...