- Advanced Semiconductor Detectors and Materials
- Semiconductor Quantum Structures and Devices
- Chalcogenide Semiconductor Thin Films
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- RNA modifications and cancer
- Spectroscopy and Laser Applications
- HVDC Systems and Fault Protection
- Cancer-related gene regulation
- Cancer Research and Treatments
- Infrared Target Detection Methodologies
- Cancer-related molecular mechanisms research
- AI in cancer detection
- Cancer, Hypoxia, and Metabolism
First Affiliated Hospital of Zhengzhou University
2024-2025
The University of Texas Southwestern Medical Center
2024
Wuhan University
2023
Shanghai Institute of Technical Physics
1997-2007
Chinese Academy of Sciences
1997-2007
Qatar University
2001
N6-Methyladenosine (m6A) is the most abundant posttranscriptional modification, and its contribution to cancer evolution has recently been appreciated. Renal common adult genitourinary cancer, approximately 85% of which accounted for by clear cell renal carcinoma (ccRCC) subtype characterized VHL loss. However, it unclear whether loss in ccRCC affects m6A patterns. In this study, we demonstrate that binds promotes METTL3/METTL14 complex formation while depletion suppresses distinctive from...
Integrating multimodal data can uncover causal features hidden in single-modality analyses, offering a comprehensive understanding of disease complexity. This study introduces fusion subtyping (MOFS) framework that integrates radiological, pathological, genomic, transcriptomic, and proteomic from 122 patients with IDH-wildtype adult glioma, identifying three subtypes: MOFS1 (proneural) favorable prognosis, elevated neurodevelopmental activity, abundant neurocyte infiltration; MOFS2...
Adaptation to low levels of oxygen (hypoxia) is a universal biological feature across metazoans. However, the unique mechanisms how different species sense deprivation remain unresolved. Here, we functionally characterize novel long noncoding RNA (lncRNA), LOC105369301, which termed hypoxia-induced lncRNA for polo-like kinase 1 (PLK1) stabilization (HILPS). HILPS exhibits appreciable basal expression exclusively in wide variety human normal and cancer cells robustly induced by...
Some results on MBE HgCdTe for the applications of IRFPAs are described. The p-type doing with As/sub 4/ was studied in terms sticking coefficient, thermal activation as well As diffusion. Various kinds surface defects and their relations to growth condition were classified. Results twin-free CdTe (211) composite substrates Si FPA presented.