A5101613753- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- Reproductive tract infections research
- Nutrition and Health in Aging
- HIV, Drug Use, Sexual Risk
- Long-Term Effects of COVID-19
- COVID-19 and Mental Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Immune Cell Function and Interaction
- Reproductive System and Pregnancy
- Sex work and related issues
- Herpesvirus Infections and Treatments
- Microbial infections and disease research
- Body Composition Measurement Techniques
- COVID-19 epidemiological studies
- HIV, TB, and STIs Epidemiology
- Blood Pressure and Hypertension Studies
- Clinical Nutrition and Gastroenterology
- Nutritional Studies and Diet
- Metabolism, Diabetes, and Cancer
- Diabetes Management and Education
- Bacterial Infections and Vaccines
- Dysphagia Assessment and Management
- COVID-19 Clinical Research Studies
- Prenatal Substance Exposure Effects
Jiangsu Provincial Center for Disease Control and Prevention
2014-2024
First Hospital of China Medical University
2021
China Medical University
2021
Chinese Center For Disease Control and Prevention
2010
Center for Disease Control
2010
Southeast University
2006
To examine outcomes of a peer-led, community-based intervention providing rapid HIV testing and case management for linkage to care untested men who have sex with (MSM) in China.Rapid was performed by trained peer volunteers organisation (CBO) three cities Jiangsu province at MSM-oriented venues. MSM screened positive were referred accompanied local government health agencies (Centres Disease Control Prevention (CDC)) confirmatory provided social support up 1 month. Data the programme...
Sarcopenia is characterized by progressive loss of muscle mass and function due to aging. DNA methylation has been identified play important roles in the dysfunction skeletal muscle. The aim our present study was explore whole blood sample-based changes function-related factors patients with sarcopenia.
Abstract Objectives Frailty is a prevalent geriatric condition that significantly impacts the health of older adults. This study aimed to examine prevalence frailty among Chinese adults aged ≥ 65 years and assess its association with adverse outcomes. Method included 20,724 in Jiangsu Province, China, utilizing random, stratified, multistage cluster sampling approach. was assessed using 5-item FRAIL scale. Geriatric outcomes, such as independence activities daily living (ADL), cognitive...
Abstract Backgrounds Fat infiltration of skeletal muscle has been recognized as a common feature many degenerative disorders. Retinol binding protein 4 (RBP4) is an adipokine that demonstrated to be correlated with the presence and severity sarcopenia in elderly. However, exact role underlying mechanism RBP4 atrophy remains unclear. Methods Denervation‐induced model was constructed wild‐type knockout mice. To modify expression RBP4, mice were received intramuscular injection retinol‐free...
The aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio, also known as De Ritis has been reportedly associated with malnutrition which plays a crucial role in sarcopenia. aim of this study was to examine the relationship between AST/ALT ratio and sarcopenia Chinese community-dwelling elderly.A cross-sectional 2751 participants (1343 men 1408 women) aged ≥60 years performed. Appendicular skeletal muscle mass index (ASMI), grip strength, gait speed were measured diagnose...
In this study, the phenotypic and genotypic resistance to fluoroquinolones in Neisseria gonorrhoeae isolated Jiangsu Province, China, was analysed. vitro susceptibility testing of eight antimicrobial agents, including ciprofloxacin levofloxacin, against 95 clinical isolates carried out. Detection mutations gyrA parC genes performed by sequence analysis. The demonstrated 100 % 98.9 non-susceptibility levofloxacin. All were susceptible cefotaxime ceftriaxone. For cefepime, spectinomycin...
Men who have sex with men (MSM) in China face high rates of HIV and syphilis infection exacerbated by internal migration. Studies on the differences epidemics changing trends high-risk behaviors geographic distribution between resident migrant MSM Jiangsu, were conducted. recruited from 14 surveillance sites serial cross-sectional study. Data demographics, sexual behaviors, prevalence collected. Participants classified as residents or migrants based household registration. During 2010-2014,...
SUMMARY Mycoplasma infections are most frequently associated with disease in the urogenital or respiratory tracts and, cases, mycoplasmas infect host persistently. In HIV-infected individuals prevalence and role of genital has not been well studied. To investigate six species risk factors for infection Jiangsu province, first-void urine venous blood samples were collected epidemiological questionnaires administered after informed consent. A total 1541 HIV/AIDS patients recruited this study....
ObjectiveOngoing symptoms which originated from coronavirus disease 2019 (COVID-19) infections threaten the health of a broad population patients. With recent changes in COVID-19 control measures China, medical staff members are currently experiencing high level stress. This study aimed to investigate prevalence ongoing symptomatic and explore potential association between stress COVID symptoms.MethodsFrom January 17th February 2, 2023, primary Jiangsu Province were surveyed using...
Natural killer (NK) cells are believed to play a role in human immunodeficiency virus 1 (HIV-1) disease progression, and NK cell levels reduced individuals with chronic HIV-1 infection. In the present study, we compared frequency phenotype of peripheral blood CD3-CD56+ infected patients China who were through different routes transmission, including heterosexual homosexual sexual contact, transmission injection drug use or importation products. The results showed significantly numbers no...
To examine trends in HIV testing, late diagnosis and associated factors among men who have sex with (MSM) Jiangsu province, China.Four consecutive community-based cross-sectional surveys were conducted MSM from 2011 to 2014 eight cities the province. Participants recruited venues via internet. bio-behavioral collect demographic behavioral data measure infection. HIV-infected participants CD4 counts less than 350 cells/uL defined as having a diagnosis. Chi-square trend tests used compare...
Abstract Context Prediabetes is associated with an increased risk of physical disability, yet no studies have assessed the extent to which muscle quality, a measure reflecting functionality, was altered in prediabetes and its specific phenotype. Objective We evaluated their associations general US population mediation analysis. Methods This cross-sectional study based on National Health Nutrition Examination Survey 2011-2014. Participants were stratified as having isolated defect (impaired...
Objectives: The aim of the study was to explore factors that may influence mental health status HIV-infected patients, and figure out a method could effectively classify patients by evaluating severity their problems. Methods: Eighty-five were recruited divided into two groups: low risk group (LRG, n = 38) high (HRG, 47). All finished Symptom Check-List 90 Revised (SCL-90-R) which is multidimensional questionnaire designed screen for broad range psychological Results: SCL-90-R scores HRG...
The aim of this study was to develop a small interfering RNA (siRNA) against the expression KIR3DL1 receptor on natural killer (NK) cells, in order promote ability NK cells destroy human immunodeficiency virus (HIV)-infected and thus prevent failure siRNA therapy targeting type 1 (HIV-1) among HIV-1 infected patients vitro.A synthesized then modified with cholesterol, methylene, sulfate. inhibitory action siRNAs primary cultured detected. amount IFN-γ TNF-α secretions measured. intended...
OBJECTIVES: The aims of this study were to update the latest data on prevalence hypertension (HTN) in elderly Chinese population and assess relationships between new anthropometric indices HTN.METHODS: Data obtained from Basic Public Health Service (BPHS) survey for Jiangsu Province, China. A total 944,760 people aged 65 years older included study. Blood pressure was measured by trained investigators. Body weight, body mass index (BMI), waist circumference (WC), waist-to-height ratio (WtHR),...
Introduction In times of epidemic outbreaks, healthcare workers (HCWs) emerge as a particularly vulnerable group. This cross-sectional study endeavors to assess the COVID-19 infection rate among primary HCWs in Jiangsu Province subsequent implementation adjusted prevention and control strategies. Methods From January 17 February 2, 2023, an extensive survey was conducted Province, employing self-designed questionnaire. Logistic regression analysis utilized identify factors associated with...
Cytokine-induced killer (CIK) cells are immune effector characterized by co-expression of CD3 and CD56 molecules. We examined the quantities CIK changes these cell expressing NK receptors in HIV-1-positive children infected via mother-to-child transmission. The percentage was quantified surface receptor profiles 18 HIV-1-infected were examined. found that percentages dramatically increased children. Furthermore, expressions CD16, NKp30, NKp44, NKp46, NKp80 CD244 on decreased, while KIR3DL1...
To evaluate the value and feasibility of capillary glucose assessment, combined with other non-laboratory measures, in screening for diabetes prediabetes community.In this cross-sectional study, we assessed fasting glucose, plasma both values after 2-h oral tolerance tests a total 3736 samples. We determined optimal threshold using receiver-operating characteristic curve analysis. The effect methods variables, such as age, BMI waist circumference, was according to area under curve.There...