A5053544716- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Ovarian cancer diagnosis and treatment
- Respiratory Support and Mechanisms
- Ferroptosis and cancer prognosis
- PARP inhibition in cancer therapy
- COVID-19 epidemiological studies
- Lung Cancer Research Studies
- Minerals Flotation and Separation Techniques
- Extraction and Separation Processes
- Healthcare professionals’ stress and burnout
- HER2/EGFR in Cancer Research
- Advancements in Semiconductor Devices and Circuit Design
- Pancreatic and Hepatic Oncology Research
- Airway Management and Intubation Techniques
- Cancer Treatment and Pharmacology
- Vitamin C and Antioxidants Research
- Synthesis and Biological Evaluation
- Cancer Risks and Factors
- Cancer Genomics and Diagnostics
- Peptidase Inhibition and Analysis
- COVID-19 and healthcare impacts
- Dielectric materials and actuators
- Nutritional Studies and Diet
Southeast University
2022-2025
China University of Geosciences
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Southeast University
2024
Liverpool School of Tropical Medicine
2024
Awake prone positioning has been reported to reduce endotracheal intubation in patients with coronavirus disease 2019 (COVID-19)-related acute hypoxemic respiratory failure (AHRF). However, it is still unclear whether using the awake for longer periods can further improve outcomes.
Poly (ADP-ribose) polymerase (PARP) inhibitors are a new maintenance therapy option for patients with ovarian cancer (OC). To evaluate the efficacy and influencing factors of novel PARP inhibitor niraparib treatment Chinese advanced OC. In this retrospective multicenter real-world study OC from 15 hospitals throughout China were enrolled. The primary endpoint was progression-free survival (PFS) secondary endpoints included time to discontinuation safety. Least Absolute Shrinkage Selection...
Recent studies suggest that neutrophil elastase inhibitor (Sivelestat) may improve pulmonary function and reduce mortality in patients with acute respiratory distress syndrome. We examined the association between receipt of sivelestat improvement oxygenation among syndrome (ARDS) induced by COVID-19. A large multicentre cohort study ARDS COVID-19 who had been admitted to intensive care units (ICUs). used propensity score matching compare outcomes treated those were not. The differences...
Gray mold, caused by Botrytis cinerea, poses an escalating threat to ginseng production in China. Excessive application of chemical fungicides has resulted severe resistance development. To elucidate the mechanism B. cinerea pyrimethanil, transcriptomic comparisons were conducted between resistant (HRG21) and sensitive (FSG43) strains following exposure pyrimethanil for 2 6 h. GO KEGG analyses identified differential expression genes associated with ABC MFS transporters as well methionine...
Anlotinib is a novel oral small-molecule multi-target tyrosine kinase inhibitor that has been approved for treating non-small cell lung cancer. However, its efficacy and safety among patients with advanced gynecological cancer have not comprehensively evaluated. We conducted this study to address issue in the real-world setting.Data from treated persistent, recurrent or metastatic were collected 17 centers August 2018. The database lock-time was on March 2022. administered orally days 1-14...
ObjectiveOngoing symptoms which originated from coronavirus disease 2019 (COVID-19) infections threaten the health of a broad population patients. With recent changes in COVID-19 control measures China, medical staff members are currently experiencing high level stress. This study aimed to investigate prevalence ongoing symptomatic and explore potential association between stress COVID symptoms.MethodsFrom January 17th February 2, 2023, primary Jiangsu Province were surveyed using...
Patients (363 in total) with stomach adenocarcinoma from The Cancer Genome Atlas (TCGA) cohort were included. An autoencoder was constructed to integrate the RNA sequencing, miRNA and methylation data. features of bottleneck layer used perform k-means clustering algorithm obtain different subgroups for evaluating prognosis-related risk adenocarcinoma. model's robustness verified using a 10-fold cross-validation (CV). Survival analyzed by Kaplan-Meier method. Univariate multivariate Cox...
Introduction In times of epidemic outbreaks, healthcare workers (HCWs) emerge as a particularly vulnerable group. This cross-sectional study endeavors to assess the COVID-19 infection rate among primary HCWs in Jiangsu Province subsequent implementation adjusted prevention and control strategies. Methods From January 17 February 2, 2023, an extensive survey was conducted Province, employing self-designed questionnaire. Logistic regression analysis utilized identify factors associated with...
Objective: The variety of ongoing symptoms originated from COVID-19 infections are affecting a broad population patients by posing threat to their health. With the recent changes control measures in China, medical staff members currently experiencing high level stress. This study aims investigate prevalence symptomatic and explore any potential associations between stress resulting symptoms. Methods: From January 17th February 2nd, 2023, survey was conducted among primary Jiangsu Province...
Abstract Background Recent studies suggest that neutrophil elastase inhibitor (Sivelestat) may improve pulmonary function and reduce mortality in patients with acute respiratory distress syndrome. We examined the association between receipt of sivelestat improvement oxygenation among syndrome (ARDS) induced by COVID-19. Methods A large multicentre cohort study ARDS COVID-19 who had been admitted to intensive care units (ICUs). used propensity score matching compare outcomes treated those...
Objective: This study aims to evaluate the prevalence of long COVID infections and their influencing factors among primary HCWs after epidemic control policy adjustment in Jiangsu. Methods: A self-designed questionnaire was administered through on-site surveys five counties districts within Jiangsu Province from July 4 20, 2023. Results: The stood at 12.61% (95% confidence interval (CI) 11.67%-13.55%). most common symptoms were hypomnesia (4.90%), sleep difficulties (2.73%), fatigue (2.35%),...
Abstract Aims This study aims to investigate the epidemiological characteristics of COVID‐19 infection among healthcare workers, including severity, duration infection, post‐infection symptoms and related influencing factors. Methods A self‐administered questionnaire was utilized assess status primary workers in Jiangsu Province. The collected information on demographic characteristics, lifestyle habits, clinical manifestations, work environment recovery time respondents. Customized outcome...
ABSTRACT Background Endometrial cancer (EC) stands as the predominant gynecological malignancy impacting female reproductive system on a global scale. N6‐methyladenosine, cuproptosis‐ and ferroptosis‐related biomarker is beneficial to prognostic of tumor patients. Nevertheless, correlation between m6A‐modified lncRNAs ferroptosis, copper‐induced apoptosis in initiation progression EC remains unexplored existing literature. Aims In this study, based bioinformatics approach, we identified...
Abstract Modelling complex smoking histories, with more comprehensive and flexible methods, to show what profile of behavior is associated the risk different cancers remains poorly understood. This study aims provide insight into association between exposure history pan-cancer by modelling both intensity duration in a large-scale prospective cohort. Here, we used data including total 0.5 million cancer incidences 12 smoking-related cancers. To jointly interpret effects smoking, modelled...
5551 Background: Niraparib has significantly extended PFS as 1st-L MT OC in PRIMA/PRIME. Due to the more complex treatment and status of patients (pts) clinal practice, real-world data is needed verify efficacy safety Niraparib. Meanwhile, exploring link between clinical characters PFS, may establish a model predict benefits. Methods: This retrospective multicentric study recruiting pts received from fourteen hospitals throughout China Jan. 2019 Dec. 2021. The database lock-time was on 31st,...