A5110081587- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Immune cells in cancer
- Frailty in Older Adults
- Cardiovascular Function and Risk Factors
- Innovative concrete reinforcement materials
- COVID-19 and healthcare impacts
- Congenital heart defects research
- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Fullerene Chemistry and Applications
- Hereditary Neurological Disorders
- Structural Load-Bearing Analysis
- Genetic Associations and Epidemiology
- BIM and Construction Integration
- Engineering Structural Analysis Methods
- Retinal Imaging and Analysis
- Sodium Intake and Health
- Heavy Metal Exposure and Toxicity
- Dietary Effects on Health
- Epigenetics and DNA Methylation
- Electromagnetic Compatibility and Measurements
- Neurological diseases and metabolism
- Chronic Kidney Disease and Diabetes
- Cardiovascular Issues in Pregnancy
Tonghua Normal University
2025
Sichuan University
2024
West China Hospital of Sichuan University
2024
Shanghai East Hospital
2024
Chinese PLA General Hospital
2024
PLA Academy of Military Science
2024
Shenzhen Second People's Hospital
2024
Harbin Medical University
2024
First Affiliated Hospital of Henan University of Science and Technology
2024
Shenzhen University
2024
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) represent a significant global burden of morbidity mortality, with being the primary cause death in affected patients. The pathogenesis injury, however, remains complex issue. In recent years, role immune system has attracted extensive attention worldwide. Despite advancements our understanding various subtypes, limitations persist both prevention treatment. This review investigates immunopathogenesis ALI/ARDS, aiming to...
palmitoylation, a reversible post-translational modification, is initiated by the DHHC family of palmitoyltransferases and reversed several acyl protein thioesterases. However, role mechanisms for palmitoylation in renal fibrosis have not been elucidated. Here we show DHHC9 were downregulated fibrotic kidneys mouse models chronic kidney disease (CKD) patients. Ablating tubular cells aggravated, while inducing overexpression with adeno-DHHC9 transfection or iproniazid treatment protected...
Abstract Background Changes in economy and dietary guidelines brought a great shock to diet quality meal behaviors, but if these transformations have extended minerals intake their sources was still poorly understood. It is essential evaluate time trends inform policy makers. Objective To investigate among U.S. adults. Methods This analysis used data collected by 24-h recalls from adults (≥ 20 years) NHANES (1999-March 2020). Minerals intake, age-adjusted percentage of participants meeting...
Abstract Aims This study sought to assess the effect of treatment sacubitril/valsartan (S/V) on improving cardiac function and reversing remodelling in patients with acute coronary syndrome (ACS) complicated heart failure reduced ejection fraction after percutaneous intervention (PCI). Methods results We enrolled 275 ACS left ventricular PCI. The were divided into routine S/V groups according drugs. symptoms, N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) concentrations,...
This paper presents the work of constructing Chinese adult anatomical models and their application in evaluation radio frequency (RF) electromagnetic field exposures. The original dataset was obtained from photos sliced frozen cadavers Visible Human Project. Details preparing cadaver for slicing procedures which may influence structures are discussed. Segmentation reconstruction were performed mainly manually by experienced anatomists. reconstructed represent average twenties thirties....
Recent studies suggest that neutrophil elastase inhibitor (Sivelestat) may improve pulmonary function and reduce mortality in patients with acute respiratory distress syndrome. We examined the association between receipt of sivelestat improvement oxygenation among syndrome (ARDS) induced by COVID-19. A large multicentre cohort study ARDS COVID-19 who had been admitted to intensive care units (ICUs). used propensity score matching compare outcomes treated those were not. The differences...
Abstract Real-world data on effectiveness and safety of a single non-vitamin K antagonist oral anticoagulant in the Chinese population with atrial fibrillation (AF) are limited. This study reports characteristics patients treated edoxaban factors associated dosing patterns from routine care China. ETNA-AF-China (NCT04747496) is multicentre, prospective, observational enrolling edoxaban-treated four economic regions targeted 2-year follow-up. Of 4930 AF (mean age: 70.2 ± 9.5 years; male,...
Abstract Acute retinal ischemia and ischemia-reperfusion injury are the primary causes of neural cell death vision loss in artery occlusion (RAO). The absence an accurate mouse model for simulating ischemic process has hindered progress developing neuroprotective agents RAO. We developed a unilateral pterygopalatine ophthalmic (UPOAO) using silicone wire embolization combined with carotid ligation. survival ganglion cells visual function were evaluated to determine duration ischemia....
The species of Ramaria are coralloid-fungi with intricately branched and vividly coloured basidiomata. There many studies on the genus in China, but molecular phylogenetic analysis is rarely employed. In this study, we performed a multigene to identify Shanxi Province northern China. Phylogenetic analyses based four loci, internal transcribed spacer region nuclear ribosomal DNA (ITS), large subunit (nrLSU), ATPase 6 (atp6), mitochondrial small (mtSSU), revealed 13 from our collections....
Previous studies have identified a positive link between the visceral adiposity index (VAI) and diabetes in specific populations. Our investigation focused on examining this association normoglycemic adults Japan.
Summary Spermatogonial stem cells (SSCs) have the ability to self-renew and offer a pathway for genetic engineering of male germ line. Cryopreservation SSCs has potential value treatment infertility, spermatogonial transplantation, so on. In order investigate cryopreservation effects different cryoprotectants on murine SSCs, 0.2 M low-density lipoproteins (LDL), trehalose soybean lecithin were added cryoprotective medium, respectively, frozen at −80°C or −196°C. The results indicated that...
The fibroblast growth factor receptor (FGFR) signaling pathway plays important roles in cellular processes such as proliferation, differentiation, and migration. In this study, we highlighted the potential of FGFR inhibitors bearing (S)-3,3-difluoro-1-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-indene scaffold containing a crucial 3-pyridyl group for treatment mutant cancers. representative compound (S)-23, which was identified through comprehensive evaluation, exhibited potent antiproliferative...
Abstract Background Recent studies suggest that neutrophil elastase inhibitor (Sivelestat) may improve pulmonary function and reduce mortality in patients with acute respiratory distress syndrome. We examined the association between receipt of sivelestat improvement oxygenation among syndrome (ARDS) induced by COVID-19. Methods A large multicentre cohort study ARDS COVID-19 who had been admitted to intensive care units (ICUs). used propensity score matching compare outcomes treated those...
The role of cardiopulmonary exercise testing (CPET) parameters in evaluating the functional severity coronary disease remains unclear. aim this study was to quantify O2-pulse morphology and investigate its relevance predicting stenosis, using Murray law-based quantitative flow ratio (μQFR) as reference. CPET μQFR were analyzed 138 patients with stable artery (CAD). quantified through calculating slope ratio. presence plateau defined according best cutoff value for ≤ 0.8. optimal 0.8 0.4,...
<title>Abstract</title> Background The role of serum albumin on acute kidney injury (AKI) remains controversial. Additionally, research this relationship in sepsis patients is sparse. Therefore, aimed to investigate the between level and probability AKI with sepsis. Methods This study was a retrospective cohort analysis across United States 2014 2015 eICU Collaborative Research Database (eICU-CRD). To estimate by univariate, multivariate logistic regression smooth curve fitting analysis....
Preeclampsia is a pregnancy disorder that seriously affects the outcome of mothers and infants lacks effective prediction diagnosis methods. ELABELA second endogenous ligand apelin receptor (APJ) associated with pathogenesis preeclampsia. In previous study, authors found downregulation expression closely related to late-onset preeclampsia, which may be marker for clinical this again collected 120 maternal blood samples, including 60 pregnant women medical ELISA results showed serum...