A5111134388- Gout, Hyperuricemia, Uric Acid
- Advanced Battery Materials and Technologies
- Metallurgical Processes and Thermodynamics
- Catalytic Processes in Materials Science
- Metal-Organic Frameworks: Synthesis and Applications
- Veterinary medicine and infectious diseases
- Head and Neck Cancer Studies
- Effects of Radiation Exposure
- Aluminum Alloy Microstructure Properties
- Alcohol Consumption and Health Effects
- Fatty Acid Research and Health
- Inflammasome and immune disorders
- Cardiovascular Function and Risk Factors
- Advanced materials and composites
- Carcinogens and Genotoxicity Assessment
- Advancements in Battery Materials
- Liver Disease Diagnosis and Treatment
- Per- and polyfluoroalkyl substances research
- Gut microbiota and health
- Heart Rate Variability and Autonomic Control
- Phytoestrogen effects and research
- Aerospace and Aviation Technology
- Silk-based biomaterials and applications
- Photopolymerization techniques and applications
- Membrane Separation Technologies
Chongqing Medical University
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2025
First Affiliated Hospital of Chengdu Medical College
2024-2025
Hunan Institute of Technology
2023-2024
Anhui University of Science and Technology
2024
Second Military Medical University
2024
Eastern Hepatobiliary Surgery Hospital
2024
Shanghai Jiao Tong University
2024
Guizhou University
2024
Guizhou Provincial People's Hospital
2024
Abstract Drug‐induced liver injury (DILI) is a significant global health issue that poses high mortality and morbidity risks. One commonly observed cause of DILI acetaminophen (APAP) overdose. GSDME an effector protein induces non‐canonical pyroptosis. In this study, the activation GSDME, but not GSDMD, in tissue mice patients with APAP‐DILI reported. Knockout rather than protected them from APAP‐DILI. Mice hepatocyte‐specific rescue reproduced APAP‐induced injury. Furthermore, alterations...
Dose- and time-response curves were combined to assess the potential of comet assay in radiation biodosimetry. The neutral was used detect DNA double-strand breaks lymphocytes caused by γ-ray irradiation. A clear dose-response relationship with using found at different times after irradiation (p < 0.001). also within 72 h for repair vitro human presented a nice model, smooth, three-dimensional plane model obtained when two combined.
We recently found that butyrate could ameliorate inflammation of alcoholic liver disease (ALD) in mice. However, the exact mechanism remains incompletely comprehended. Here, we examined role on ALD-associated through macrophage (Mψ) regulation and polarization using vivo vitro experiments. For experiments, C57BL/6J mice were fed modified Lieber-DeCarli liquid diets supplemented with or without ethanol sodium (NaB). After 6 weeks treatment, euthanized associated indicators analyzed....
To evaluate the predictive value of triglyceride-glucose waist circumference index (TyG-WC) for hyperuricemia (HUA) risk in hypertensive population. This prospective cohort study involved 831 patients with normal uric acid levels, who underwent continuous health examinations five years. Participants were categorized into four groups based on baseline TyG-WC quartiles, and incidence was monitored each group. Hazard ratios (HRs) 95% confidence intervals (95% CIs) HUA calculated using Cox...
Abstract Real-world data on effectiveness and safety of a single non-vitamin K antagonist oral anticoagulant in the Chinese population with atrial fibrillation (AF) are limited. This study reports characteristics patients treated edoxaban factors associated dosing patterns from routine care China. ETNA-AF-China (NCT04747496) is multicentre, prospective, observational enrolling edoxaban-treated four economic regions targeted 2-year follow-up. Of 4930 AF (mean age: 70.2 ± 9.5 years; male,...
In glioma molecular subtyping, existing biomarkers are limited, prompting the development of new ones. We present a multicenter study-derived consensus immune-related and prognostic gene signature (CIPS) using an optimal risk score model 101 algorithms. CIPS, independent factor, showed stable powerful predictive performance for overall progression-free survival, surpassing traditional clinical variables. The correlated significantly with immune microenvironment, indicating potential...
Blockade therapy of immune checkpoint with anti-programmed cell death (PD)-1 antibody has achieved tremendous success on the treatment numerous malignant tumors, whereas there is still a problem low response rate. In present study, complement α-linolenic acid (ALA) impact PD-1 immunotherapy for hepatocellular carcinoma (HCC) was investigated. We found that ALA combined exerted superior in inhibiting tumor growth. Moreover, combination significantly changed diverse T subsets and ant-tumor...
Photopolymerization of acrylate monomers has been the focus research for quite a long time, but most researches concentrated on using exogenous radical species as means to achieve photo-induced polymerization. Herein, we exploit energy transfer process between luminescent molecule and monomer accomplish two-component photoinduced polymerization reaction, explored universality this strategy. Via choice thiochromanone template study, photochemistry processes involved were in depth. The effect...
In conventional photo-induced polymerization strategies, the active species that initiate reaction tend to be exogenous radical species. Inspired by cycloaddition reactions, in this study we investigated from perspective of energy transfer processes. Utilizing low-energy, highly reactive triplet olefin molecules as acceptors, a strategy without need for components was developed. Triplet various sources were able induce polymerization, demonstrating excellent versatility strategy. The...
The incidence of endometrial cancer (EC) is increasing worldwide, but the specific mechanism coagulation dysfunction in EC not fully understood. objective present study was to explore relationship between autonomic nervous system function and patients with using heart rate variability (HRV) analysis. included 100 who were treated at Department Gynecological Oncology First Affiliated Hospital Bengbu Medical University (Bengbu, China) from December 2021 March 2023. A 5‑min resting...
The present study investigates cytogenetic damage in lymphocytes, derived from three victims who were unfortunately exposed to cobalt-60 (60Co) radiation (the 1999 accident occurred a village China's Henan province). Case A of the was higher dose 60Co than Cases B and C. chromosomal aberrations, cytokinesis-block micronucleus (CBMN, CBMN assay), DNA double-strand breaks (DSBs, comet assay) examined this are biomarkers for abnormalities. After lymphocytes collected cultured, frequencies...
Recent evidence suggests that diabetes is a risk factor for thyroid nodules. However, the relationship between complications of type 2 and nodules remains unclear. This present study aims to investigate association diabetes.This retrospective collected 4696 adult inpatients with January 2021 December 2021. The examined in this paper included diabetic nephropathy, peripheral neuropathy, eye disorder, vascular disease.A total patients participated study, whom 19.6% had Among all complications,...
Abstract Objective To investigate whether cavitation induced by ultrasound stimulated microbubbles (USMB) can enhance the therapeutic effect of colchicine and reduce its side effects on acute gouty arthritis (AGA) in rats. Materials Methods Each rat underwent right ankle joint contrast-enhanced (CEUS) before following treatment. The area under curve (AUC) CEUS after among groups were compared to contrast impact blood perfusion rats with cavitation. symptoms AGA evaluated based 24-hour...
Surround-view depth estimation is a crucial task aims to acquire the maps of surrounding views. It has many applications in real world scenarios such as autonomous driving, AR/VR and 3D reconstruction, etc. However, given that most data driving dataset collected daytime scenarios, this leads poor model performance face out-of-distribution(OoD) data. While some works try improve robustness under OoD data, these methods either require additional training or lake generalizability. In report, we...