A5020580496- Lung Cancer Treatments and Mutations
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Lung Cancer Research Studies
- Kruppel-like factors research
- Lung Cancer Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Cancer Immunotherapy and Biomarkers
- Bone and Joint Diseases
- Radiopharmaceutical Chemistry and Applications
- Advanced NMR Techniques and Applications
- Immune Cell Function and Interaction
- Thyroid Cancer Diagnosis and Treatment
- Fibroblast Growth Factor Research
- Quantum many-body systems
- Clinical practice guidelines implementation
- Biomarkers in Disease Mechanisms
- Melanoma and MAPK Pathways
- Advanced Breast Cancer Therapies
- Genetic factors in colorectal cancer
- Sulfur Compounds in Biology
- Cancer Genomics and Diagnostics
- Diet, Metabolism, and Disease
- Ethics in medical practice
- HER2/EGFR in Cancer Research
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Princess Margaret Cancer Centre
2024-2025
University Health Network
2025
Queen's University
2025
Xuzhou Medical College
2025
Shanxi Academy of Medical Sciences
2024
Shanxi Medical University
2024
Qilu Hospital of Shandong University
2020-2024
Fudan University Shanghai Cancer Center
2024
Second Hospital of Tianjin Medical University
2023-2024
Manual extraction of real-world clinical data for research can be time-consuming and prone to error. We assessed the feasibility using natural language processing (NLP), an AI technique, automate patients with advanced lung cancer (aLC). external validity our NLP-extracted by comparing findings those reported in literature. Patients diagnosed stage IIIB or IV between January 2015 December 2017 at Princess Margaret Cancer Centre who received least one dose systemic therapy were included....
Background Although the triglyceride-glucose (TyG) index levels have been shown to be a reliable predictor of major adverse cardiovascular events (MACE), few studies investigated their association with heart failure (HF), especially in patients on dialysis. We therefore aimed investigate relationship between TyG and incidence HF undergoing maintenance hemodialysis (MHD). Methods A total 183 participants who underwent MHD Blood Purification Center Affiliated Hospital Xuzhou Medical University...
Universality often emerges in low-energy equilibrium physics of quantum many-body systems, despite their microscopic complexity and variety. Recently, there has been a growing interest studying far-from-equilibrium dynamics systems. Such usually involves highly excited states beyond the traditional theory description. Whether universal behaviors can also emerge such non-equilibrium is central issue at frontier dynamics. Here we report experimental observation by monitoring spin...
Background: little is known about the incidence and characteristics of multisystem immune-related adverse events (irAEs) associated with dual-agent ipilimumab nivolumab use. Methods: A retrospective cohort review was completed that included cancer patients seen at Juravinski Cancer Centre who received least one dose from 2018 to 2022. Patient characteristics, types, irAEs were recorded. Multivariate logistic cox regressions completed, comparing those developed irAEs, single irAE, no irAE....
结直肠癌是消化道常见恶性肿瘤之一，在我国发病率呈上升趋势，病死率居高不下，亟须采取公共卫生措施降低其疾病负担。国内外研究表明，开展结直肠癌筛查可实现早诊早治，有效降低结直肠癌发病率及病死率。现对结直肠早癌筛查领域近十年研究进展及热点问题进行综述。.
To explore the histopathological factors affecting stiffness of papillary thyroid carcinoma (PTC).
In recent years, the incidence rate of early-onset colorectal cancer (EOCRC) continues to rise, but its pathogenesis is still unclear. EOCRC different from late-onset in terms clinical and molecular pathological features, their treatment strategies are same, due a lack specific guidelines screening, diagnosis for EOCRC. This article summarizes research progress epidemiological characteristics, risk factors, pathogenesis, prevention screening EOCRC, order provide theoretical basis patients with
To investigate the risk factors of venous thrombosis in patients with polycythemia vera (PV) and establish a prediction model for thrombosis.
Objective: To construct a knowledge, attitude and practice evaluation system of nursing humanistic care, to provide reference for improving construction. Methods: Based on literature analysis, the draft was sorted out, two rounds Delphi expert consultation were conducted 28 experts, items modified according opinions. Results: The enthusiasm coefficients 100% 96.4%, authority 0.888 0.870, coordination 0.342 0.467, respectively, which statistically significant (P<0.05) . final care clinical...
The incidence of colorectal cancer in China is increasing year by year, and the mortality rate remains high. To reduce cancer-related social economic burdens, awareness research on great significance. It necessary to explore diagnosis, endoscopic treatment, prevention. Focuses should also be placed actively screening for improving advanced adenomas detection rate, thereby building a prevention treatment system which meets national conditions...
Objective: To evaluate the screening performance of hypersensitive quantitative fecal immunochemical test (hs-qFIT) and qualitative occult blood (FOBT) for colorectal cancer advanced adenoma. Methods: Consecutive participants scheduled to undergo colonoscopy from April 2020 2021 in Qilu Hospital Shandong University were included study. All 50-75 years old at moderate high risk cancer. Participants completed hs-qFIT two kinds FOBTs (colloidal gold method chemical-immunization method) before...
Objective: To investigate the mechanism of signal transducer and activator transcription 3 (STAT3) cancer associated fibroblasts (CAF) jointly generate chemo-resistance in epithelial-ovarian their effect on prognosis. Methods: A total 119 patients with high-grade ovarian serous who received surgery Cancer Hospital Chinese Academy Medical Sciences from September 2009 to October 2017 were collected. The clinico-pathological data follow-up complete. Multivariate Cox regression model was used...
Objective: To explore the clinical and laboratory characteristics of SF3B1 gene mutations in myeloproliferative neoplasms (MPN) patients. Methods: The data 273 MPN patients who were diagnosed treated Second Hospital Tianjin Medical University from November 2017 to March 2023 retrospectively analyzed. There 133 males 140 females, with a median age M(Q1,Q3)of 56(46, 67) years. molecular biology cytogenetic detected by second-generation sequencing (NGS) R+G banding techniques, mutation Results:...
Objective: To analyze the risk factors of thrombosis in patients with JAK2V617F mutation positive myeloproliferative neoplasms (MPN). Methods: A total 223 MPN Second Hospital Tianjin Medical University from September 2017 to May 2023 were retrospectively enrolled, including 111 males and 112 females, aged [M(Q1,Q3)] 57(21,66) years. According presence or absence thromboembolism during follow-up, divided into group (n=102) non-thrombosis (n=121). The clinical characteristics, laboratory...
Objective: To evaluate the efficacy and safety of pegylated interferon alpha-2b (PEG-IFN-α2b) in treatment myeloproliferative neoplasm (MPN). Methods: Thirty-four MPN patients receiving PEG-IFN-α2b Second Hospital Tianjin Medical University from August 2019 to October 2022 were prospectively included. Among patients, 9 male 25 female, median age [M (Q1, Q3)] was 57 (19, 78) years. Patients' clinical characteristics collected follow-up performed. As January 30, 2023, period [M(Q1, 24 (16, 33)...
This article investigated an occupational chronic benzene poisoning incident that occurred in a sealing material factory Hebei Province September 2019, analyzed the clinical data of workers, to explore causes poisoning, and summarize diagnosis treatment characteristics outcome. According GBZ 68-2013 "Diagnosis Occupational Benzene Poisoning", total 12 cases were diagnosed among 20 including 2 mild 7 moderate 3 severe poisoning. Both patients had recovered after treatment. Severely poisoned...
Hydrogen sulphide poisoning is an acute event that occurs frequently in summer. A case of hydrogen a confined space August 2018 was investigated and clinical data were analyzed. This typical sulfide gas space. The main cause the accident lack occupational protection illegal rescue. Among 5 patients, 3 died, 1 patient had long-term sequelae nervous system damage such as cortical blindness,...
Fish bile poisoning may damage human liver and kidney, causing degeneration necrosis. Can also brain cells heart muscle, resulting in nervous system cardiovascular lesions. This paper reports a case of patient who developed multiple organ dysfunction syndrome (MODS) after oral administration fish with Xiexin folk prescription for eye disease. In January 2020, he went to the occupational diseases department emergency Qilu hospital. After receiving hemoperfusion, continuous renal replacement...