A5019445958- Poisoning and overdose treatments
- Paraquat toxicity studies and treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Methemoglobinemia and Tumor Lysis Syndrome
- Neonatal Health and Biochemistry
- Pesticide Exposure and Toxicity
- Infectious Encephalopathies and Encephalitis
- Alcoholism and Thiamine Deficiency
- Retinal Imaging and Analysis
- Occupational exposure and asthma
- Venous Thromboembolism Diagnosis and Management
- Electroconvulsive Therapy Studies
- Venomous Animal Envenomation and Studies
- 2D Materials and Applications
- COVID-19 diagnosis using AI
- Muscle and Compartmental Disorders
- Acute Ischemic Stroke Management
- Air Quality and Health Impacts
- Acute Kidney Injury Research
- Disaster Response and Management
- Chemical Safety and Risk Management
- Immune Cell Function and Interaction
- ECG Monitoring and Analysis
- Restraint-Related Deaths
- Child Nutrition and Water Access
Qilu Hospital of Shandong University
2021-2025
Shandong University
2021-2024
Wuhan University
2021
Renmin Hospital of Wuhan University
2021
Jinan University
2021
Taishan Medical University
2017
Introduction Diquat-related acute kidney injury is well-known. However, neurological disorders caused by diquat are often underestimated, and changes in the imaging findings rarely reported. We present three cases of poisoning resulting toxic encephalopathy.Case report In first case, a 20-year-old previously healthy man ingested approximately 80–100 mL diquat. He developed renal failure, disorders, respiratory failure. Central pontine myelinolysis was considered magnetic resonance (MRI), 18...
Methemoglobinemia can be inherited or acquired. Acquired forms are more common due to drugs poisonous substances that oxidize hemoglobin, and pesticide-related cases notably rare. We report a 69-year-old woman who ingested 30 mL of tebufenozide indoxacarb was asymptomatic for 3 h; however, the patient admitted hospital after 8 h, unconscious, with tachypnea, cyanosis, 61.9% methemoglobin. The administered methylene blue, mechanically ventilated, hemoperfused. Subsequently, recovered...
Acute pesticide poisoning is a major public health concern. The relationship between family function and depression in caregivers of patients with acute unclear. Therefore, this study aimed to explore the function, coping style, among provide theoretical basis intervention targets for future research. A cross-sectional was conducted Department Toxicology Occupational Disease Grade hospital Jinan, Shandong Province, from November 2022 June 2023. general data questionnaire, caring index scale,...
Diquat (1,1'-ethylene-2,2'-bipyridylium) is a type of widely used agricultural chemical, whose toxicity results in damage to numerous tissues, including the lung, liver, kidney and brain. The aim present study was establish rat model acute diquat exposure explore relationship between concentration, lung injury, order provide an experimental basis for clinical treatment. A total 140 healthy adult male Wistar rats were randomly divided into control groups. solution administered...
Diquat is a herbicide that can have deleterious effects on the kidneys, liver, heart, lungs, and central nervous system ingestion. poisoning-associated rhabdomyolysis has rarely been reported. We describe two cases of diquat poisoning with acute renal failure, myocardial damage, rhabdomyolysis. Case 1: A 17-year-old man experienced anuria after ingesting ~200 mL 16 h prior. On admission, his creatinine (400 μmol/L), urea (11.7 mmol/L), creatine kinase (2,534 IU/L), myohemoglobin (4,425...
Nitrobenzene poisoning is uncommon, with most cases occurring in the dye, paint, and other chemical industries. enters body mainly through skin, respiratory tract, oral cavity. symptoms include hypermethemoglobinemia, hemolytic anemia, liver kidney dysfunction, cardiogenic pulmonary edema, toxic encephalopathy, which endanger people’s lives. Therefore, we present a case of nitrobenzene caused by skin absorption, focusing on its clinical characteristics treatment outcomes. A 58 years-old man...
Diquat (DQ), chemically known as 1,1 ‘-ethylene-2,2’ -bipyridine, is a non-selective herbicide for leaf removal and drying. It has toxic effects on central nervous system cells, neurological lesions include axonal degeneration pontine myelolysis. At the same time, DQ can also affect activity of dopaminergic nerve cells through oxidative stress, causing reducing dopamine uptake. With increasing application in agricultural production, clinical reports neurotoxicity caused by acute poisoning...
To investigate the alterations in retinochoroidal parameters measured by optical coherence tomography (OCT) and OCT angiography (OCTA) patients with carotid artery stenosis (CAS) assess their associations digital subtraction (DSA) data. This study enrolled diagnosed CAS age-matched healthy controls. Both groups underwent OCTA examinations. DSA assessment of were performed only group. The evaluated various from OCTA, including linear vessel density (LVD), foveal avascular zone (FAZ),...
Aluminum phosphide is a highly effective insecticide for fumigation in granaries and often used rural grain storage. However, people’s awareness of its toxicity not strong. A case acute inhalation phosphine caused by the use aluminum to fumigate granary reported here. The presented with aspiration pneumonia left heart failure. patient was cured using comprehensive life support treatment, including respiratory support, antiarrhythmic blood pressure maintenance vasoactive drugs. There no...
Lambda-cyhalothrin is a new-generation pyrethroid II insecticide that neurotoxic. Most domestic and international reported cases are of oral poisoning, whereas few inhalation skin absorption poisoning have been reported. Here, we report the case 46-year-old man who was poisoned via dermal due to rupture leakage lambda-cyhalothrin pipeline. The patient developed burning sensation, eyeball pain, upper-limb tremor after exposure. After admission, cough, sputum expectoration, chest tightness,...
Benzene poisoning can cause acute myeloid leukemia (AML) through a variety of passways. Tim-3 has gained prominence as potential candidate in mediating immunosuppression tumor microenvironments. The macrophage polarization is also related to immune escape. Herein, we reported that and M2 play vital role benzene-induced AML. First, the AML C3H/He mouse model was constructed by subcutaneously injecting 250 mg/kg benzene. After six months, phenotype, cytokines, expression levels were...
Olanzapine is a widely adopted atypical antipsychotic medication used to manage schizophrenia. Reports show that the incidence rate of adverse reactions olanzapine significantly lower than those other classic medications. However, overdose may be associated with severe consequences. Herein, we report 21-year-old female patient who had taken nearly 700 mg (70 tablets) olanzapine; she was found after 30 hours. As her condition progressed, presented rhabdomyolysis, swelling in thighs and hips,...
Objective In January 2023, a rare event of collective inhalation paraquat poisoning occurred in Shandong, China. To analyze the clinical characteristics an respiratory tract through inhalation. Methods Clinical data from eight patients with were retrospectively analyzed. Results The mainly exposed to via tract. main manifestations ocular and irritation. Lung computed tomography (CT) showed that all had varying degrees lung injury, manifesting as exudative lesions. Laboratory tests revealed...
Acute organophosphorus pesticide poisoning (AOPP) with cardiac arrest has an extremely high mortality rate, and corresponding therapeutic strategies have rarely been reported. Therefore, this study aimed to explore the prognostic factors effective treatments of AOPP-related arrest. This retrospective was conducted in our department years 2018–2021. We a descriptive analysis clinical manifestations, rescue strategies, prognosis patients AOPP who had experienced successful cardiopulmonary...
To develop and confirm an individualized predictive model to ascertain the probability of deep venous thrombosis in patients with acute poisoning after undergoing hemoperfusion.Three hundred eleven who were admitted a hospital China between October 2017 February 2019 included development group. Eighty May validation The independent risk factors for examined. An was developed using regression coefficients.The number catheter indwelling days, having while being transported, elevated serum...
Background Patients with acute toxic hemoperfusion are prone to deep vein thrombosis. However, there is no risk assessment model for thrombosis in patients hemoperfusion. Therefore, we compared three commonly used models determine the most suitable of Methods Caprini, Autar, and Padua were assess poisoning admitted a grade A hospital Shandong province from October 2017 February 2019. The predictive values using receiver operating characteristic (ROC) curve analysis. Results scores 7.55 ±...
It is now understood that hematological diseases can have detrimental effects on the retina, reducing retinal capillaries, compromising visual function, and potentially causing irreversible impairment. Over years, there has been limited research macular microvascular abnormalities, such as changes in vessel density foveal avascular zone (FAZ) variations severity of these across different types blood disorders. This study aims to quantitatively assess impact various disorders retina using...
Venomous snake bites can result in irreversible damage, leading to respiratory dysfunction, bleeding disorders, kidney or serious complications. In recent years, with the popularity of online shopping China, snakes be easily purchased and kept as pets, even if some areas are not natural habitats for certain kinds snakes. A 13-year-old boy two venomous pets. On April 16, 2019,the was bitten by a
This study used the Delphi method and clinical expert discussions to develop an acute paraquat poisoning nursing pathway standardize care.In practice, especially in basic-level hospitals, there is no unified standard pattern of treatment care for patients with poisoning.An extensive literature search was gather current guidelines treating which were then compiled into a letter inquiry questionnaire sent panel 12 experts.A preliminary draft table hospitalization period 21 days established, 6,...
In this paper, the clinical data of a case accidental poisoning dimethylformamide in traffic accident was analyzed. The patient trapped driving room, his limbs were soaked for long time, and inhaled at same time. After 4 days treatment local hospital, he transferred to Department Poisoning & Occupational Diseases, Emergency Medicine Qilu Hospital Shandong University treatment. main manifestation liver damage intractable abdominal pain, which cured by active...
We report two suicidal cases of acute methyl ethyl ketone peroxide (MEKP) poisoning. A woman in her late 60s suffered from oral mucosal erosion, functional impairment the heart, liver and other organs, pulmonary inflammation, elevated inflammatory markers, pleural effusion, hypoproteinemia metabolic acidosis after administration approximately 50 mL MEKP. After admission, patient was administered hemoperfusion four times, 8 mg betamethasone for 6 days symptomatic support. Hemoperfusion had an...