- Osteoarthritis Treatment and Mechanisms
- Liver Diseases and Immunity
- Cancer Research and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gastrointestinal Tumor Research and Treatment
- Liver Disease Diagnosis and Treatment
- Connective Tissue Growth Factor Research
- Hepatitis C virus research
- Systemic Lupus Erythematosus Research
- Chromatin Remodeling and Cancer
- Mesenchymal stem cell research
- Cancer-related gene regulation
- MRI in cancer diagnosis
- Peptidase Inhibition and Analysis
- Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Glioma Diagnosis and Treatment
- Inflammatory Myopathies and Dermatomyositis
- Cancer, Hypoxia, and Metabolism
- Musculoskeletal synovial abnormalities and treatments
- Systemic Sclerosis and Related Diseases
- Immunotherapy and Immune Responses
- Growth Hormone and Insulin-like Growth Factors
State Key Laboratory of Biotherapy
2024
Sichuan University
2024
Air Force Medical University
2023-2024
Baotou Medical College
2016-2023
Inner Mongolia University of Science and Technology
2021
<title>Abstract</title> Signet ring cell carcinoma (SRCC) is a lethal malignancy with unique histologic features, characterized large vacuoles and compressed nuclei. Gastric SRCC the most common SRCC, its incidence increasing recently. However, driver genes of molecular mechanisms underlying unusual histology remain unclear. Here, we developed new type gastric mouse models gene-edited premalignant organoids validated <italic>ARID1A</italic>, one frequently mutated in as <italic>bona...
Objective: To investigate the clinical characteristics of patients with rheumatic diseases and abnormal liver function, as well determine proportion severity function abnormalities. Methods: Cross-sectional study. Data were collected from registered in Chinese Rheumatism Date Center 2011 to 2021. The analyzed this study rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), Sjogren syndrome (SS), ankylosing spondylitis (AS), gout. Patient data, including demographic [ such age, sex,...
Objective: To analyze the risk factors of polymyositis/dermatomyositis (PM/DM) complicated with malignant tumor and to construct clinical prediction model. Methods: A total 427 PM/DM patients, who were admitted Rheumatism Immunity Branch, Second Affiliated Hospital, Air Force Medical University from January 1, 2015 2021, enrolled in study, including 129 males 298 females. The mean age was (51.4±12.2) years. patients divided into control group (without tumor, n=379) case (with n=48) according...