A5103231706- Acute Ischemic Stroke Management
- Glioma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Mitochondrial Function and Pathology
- Glaucoma and retinal disorders
- Cancer, Lipids, and Metabolism
- Autoimmune Neurological Disorders and Treatments
- Health, psychology, and well-being
- Pituitary Gland Disorders and Treatments
- Neurological and metabolic disorders
- Hemoglobinopathies and Related Disorders
- Cytomegalovirus and herpesvirus research
- Adenosine and Purinergic Signaling
- Gut microbiota and health
- Retinal Imaging and Analysis
- Meningioma and schwannoma management
- Peripheral Artery Disease Management
- Neurological Disease Mechanisms and Treatments
- Neurofibromatosis and Schwannoma Cases
- Stroke Rehabilitation and Recovery
- Tryptophan and brain disorders
- Metabolomics and Mass Spectrometry Studies
- Cancer, Hypoxia, and Metabolism
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
Peking Union Medical College Hospital
2022-2024
Guangdong Academy of Medical Sciences
2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2024
Abstract Background The causal effects of gut microbiome and the development posttraumatic stress disorder (PTSD) are still unknown. This study aimed to clarify their potential association using mendelian randomization (MR). Methods summary-level statistics for were retrieved from a genome-wide (GWAS) MiBioGen consortium. As PTSD, Freeze 2 datasets originated Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group (PGC-PTSD), replicated obtained FinnGen Single nucleotide...
Background Blood pressure (BP) is a key factor for the clinical outcomes of acute ischemic stroke (AIS) receiving endovascular thrombectomy (EVT). However, effect circadian pattern BP on functional outcome unclear. Methods This multicenter, retrospective, observational study was conducted from 2016 to 2023 at three hospitals in China (ChiCTR2300077202). A total 407 patients who underwent (EVT) and continuous 24-h monitoring were included. Two hundred forty-one cases Beijing Hospital...
BACKGROUND: Iron status has been associated with functional outcomes after ischemic stroke (IS). Nonetheless, this association may be affected by confounders. We perform Mendelian randomization to clarify the causal between iron and outcome IS. METHODS: obtained summary-level statistics related biomarkers from a meta-analysis of gene-wide study conducted Genetics Status Consortium, which included 11 discovery cohorts 8 replication cohorts. also took genetic variants 4 combining results...
Anti-gamma-aminobutyric-acid type B receptor (anti-GABABR) encephalitis is a rare autoimmune condition caused by the presence of GABABR antibodies in limbic system. However, its clinical features and prognostic factors are poorly understood. In this study, we aimed to explore that affect response first-line treatment patients with anti-GABABR encephalitis.Thirty-four an initial diagnosis were retrospectively enrolled from December 2015 June 2021. Clinical experimental data recorded within 24...
Abstract BACKGROUND Systolic blood pressure (BP) is a key factor in the outcomes of patients with acute ischemic stroke (AIS) receiving endovascular thrombectomy (EVT). However, factors that mediate association between BP and clinical outcome are unclear. METHODS Consecutive AIS anterior circulation underwent continuous monitoring for 24 hours. The 3-month modified Rankin scale (mRS) score was defined as functional outcome. systolic BPI indices (BPIs) were successive variation, standard...
Craniopharyngiomas (CPs) are histologically benign tumors located in the sellar-suprasellar region. Although transcriptome development recent years have deepened our knowledge to tumorigenesis process of adamantinomatous craniopharyngioma (ACP), peritumoral immune infiltration tumor is still not well understood. In this study, weighted gene coexpression network analysis (WGCNA) was applied identify different modules based on clinical characteristics and expression, then, protein-protein...