A5068497892- Posttraumatic Stress Disorder Research
- Resilience and Mental Health
- Traumatic Brain Injury Research
- Suicide and Self-Harm Studies
- Migration, Health and Trauma
- Personality Disorders and Psychopathology
- Psychological Testing and Assessment
- Psychosomatic Disorders and Their Treatments
- Psychotherapy Techniques and Applications
- Mental Health Research Topics
- Musculoskeletal pain and rehabilitation
- Healthcare professionals’ stress and burnout
- Child Abuse and Trauma
- Mental Health Treatment and Access
- Circadian rhythm and melatonin
- Stress Responses and Cortisol
- Occupational Health and Performance
- Sleep and Work-Related Fatigue
- Counseling Practices and Supervision
- Health Systems, Economic Evaluations, Quality of Life
- Mental Health and Psychiatry
- Child and Adolescent Psychosocial and Emotional Development
- Tryptophan and brain disorders
- Adolescent and Pediatric Healthcare
- Health, psychology, and well-being
Minneapolis VA Health Care System
2016-2025
University of Minnesota
2015-2025
Twin Cities Orthopedics
2015-2025
University of Minnesota Medical Center
2009-2023
Society for Personality Assessment
2021
Minneapolis VA Medical Center
2004-2017
Institute of Behavioral Sciences
1989-2016
Veterans Health Administration
1995-2015
Health Services Research & Development
2014
United States Department of Veterans Affairs
1992-2014
<h3>Context</h3> Troops deployed to Iraq and Afghanistan are at high risk for exposure combat events resulting in mild traumatic brain injury (MTBI) or concussion posttraumatic stress disorder (PTSD). The longer-term impact of combat-related concussion/MTBI comorbid PTSD on troops' health well-being is unknown. <h3>Objective</h3> To assess longitudinal associations between symptoms reported theater psychosocial outcomes combat-deployed National Guard soldiers. <h3>Design</h3> Longitudinal...
The molecular pathology of stress-related disorders remains elusive. Our brain multiregion, multiomic study posttraumatic stress disorder (PTSD) and major depressive (MDD) included the central nucleus amygdala, hippocampal dentate gyrus, medial prefrontal cortex (mPFC). Genes exons within mPFC carried most disease signals replicated across two independent cohorts. Pathways pointed to immune function, neuronal synaptic regulation, hormones. Multiomic factor gene network analyses provided...
This article describes the development and initial validation of a new Minnesota Multiphasic Personality Inventory—2 (MMPI-2; J. N. Butcher, W. G. Dahlstrom, R. Graham, A. Tellegen, & B. Kaemmer, 1989) scale designed to detect infrequent responding in settings characterized by relatively high base rates psychopathology psychological distress. The Infrequency-Psychopathology Scale, F(p), was developed identifying set 27 MMPI-2 items answered infrequently both inpatients normative sample....
Recent studies on the neurobiology of cognition have focused ability prefrontal cortex (PFC) to support processes working memory, i.e, mnemonic by which information relevant for a correct response is temporarily maintained be reevaluated or updated trial-by-trial basis. Of most recent interest role played dopamine (DA) in spatial memory principal sulcal region PFC. Although D1 DA receptors appear modulate these monkeys, several lines research suggest that D2 could also cognitive functions....
Validated the General Behavior Inventory (GBI), revised to identify unipolar as well bipolar affective conditions, in a nonclinical sample (n = 201) against naive, interview-derived diagnoses. For and respectively, GBI had high positive (.94, .87) negative (.99, .93) predictive power with effect of prevalence considered, adequate sensitivity (.78, .76), specificity .99), selection ratios for sampling nonaffective subjects from populations research purposes. The utility several different...
Abstract Background The causal effects of gut microbiome and the development posttraumatic stress disorder (PTSD) are still unknown. This study aimed to clarify their potential association using mendelian randomization (MR). Methods summary-level statistics for were retrieved from a genome-wide (GWAS) MiBioGen consortium. As PTSD, Freeze 2 datasets originated Psychiatric Genomics Consortium Posttraumatic Stress Disorder Working Group (PGC-PTSD), replicated obtained FinnGen Single nucleotide...
Abstract The authors examined rates of and factors associated with postdeployment treatment‐seeking in a panel 424 National Guard soldiers who spent 16 months Iraq. Soldiers completed self‐report, mailed survey 3‐ to 6‐months after returning home. Approximately one third respondents reported mental health treatment. Those screened positive for problems were more likely indicate that they had received treatment compared those negative, but over half not engaged Variables related receipt...
Occupational functioning represents both an important outcome for military service members returning from Operation Iraqi Freedom (OIF) and Enduring a predictor long-term mental health functioning. We investigated the role of diagnoses, determined by structured clinical interviews, on occupational in group 262 National Guard/Reserve within 1 year 16-month OIF combat deployment. assessed at time diagnostic interviews later. hypothesized that with diagnoses posttraumatic stress disorder...
Abstract Social support is a robust correlate of posttraumatic stress disorder (PTSD) symptoms and general psychological distress (Ozer, Best, Lipsey, & Weiss, 2003). The nature the causal relationship between PTSD remains subject debate, with 2 models, social erosion causation, often used to explain findings. Despite extensive research using these no studies which we are aware have included tests both models within same series analyses, across more than time points, in veterans. These...
Although women in the military are exposed to combat and its aftermath, little is known about whether as well pre-deployment risk/protective factors differentially predict post-deployment PTSD symptoms among compared men. The current study assesses influence of combat-related stressors on women's risk developing following deployment relative men's risk.Participants were 801 US National Guard Soldiers (712 men, 89 women) deployed Iraq or Afghanistan who completed measures potential one month...
The National Institute of Mental Health Research Domain Criteria initiative (Insel et al., 2010) calls for a focus on biologically meaningful dimensional constructs in the study clinical problems. Examples are needed how can be linked to We examined two such constructs, threat sensitivity (THT+) and weak inhibitory control (INH-), operationalized using scale measures fear/fearlessness inhibition/disinhibition dimensions from established structural models, predicted symptoms multiple...
Alcohol use in the military is a significant problem. The goal of this study was to examine associations between personality, posttraumatic stress disorder (PTSD) symptoms, and postdeployment alcohol disorders (AUDs) among group Operation Iraqi Freedom (OIF) deployed National Guard soldiers, with focus on differentiating predeployment onset AUDs. Participants were 348 soldiers Iraq from March 2006 July 2007 drawn Readiness Resilience Soldiers (RINGS) study. completed self-report measures one...
After returning from an extended combat deployment to Iraq, 348 National Guard soldiers were administered the PTSD Checklist (PCL-M), and Beck Depression Inventory II (BDI-II) followed, on average, 3 months later by structured diagnostic interviews including Clinician-Administered Scale (CAPS) for Diagnostic Statistical Manual of Mental Disorders (4th ed.). There 6.5% who met criteria posttraumatic stress disorder (PTSD) based interview. The predictive validity PCL was examined contrasted...