Amber Brandolino

ORCID: 0000-0002-4232-0630
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About
Contact & Profiles
Research Areas
  • Trauma and Emergency Care Studies
  • Emergency and Acute Care Studies
  • Posttraumatic Stress Disorder Research
  • Gun Ownership and Violence Research
  • Healthcare Policy and Management
  • Stress Responses and Cortisol
  • Traumatic Brain Injury Research
  • Suicide and Self-Harm Studies
  • Cardiac Arrest and Resuscitation
  • Disaster Response and Management
  • Public Health Policies and Education
  • Migration, Health and Trauma
  • Tryptophan and brain disorders
  • Counseling Practices and Supervision
  • Restraint-Related Deaths
  • COVID-19 and healthcare impacts
  • Ultrasound in Clinical Applications
  • Resilience and Mental Health
  • Injury Epidemiology and Prevention
  • Psychological Treatments and Assessments
  • Family and Patient Care in Intensive Care Units
  • Food Security and Health in Diverse Populations
  • Primary Care and Health Outcomes
  • Cinema and Media Studies
  • Policing Practices and Perceptions

Medical College of Wisconsin
2020-2025

Froedtert Hospital
2023

The aim of this study was to identify a mortality benefit with the use whole blood (WB) as part resuscitation bleeding trauma patients.Blood component therapy (BCT) is current standard for resuscitating patients, WB emerging product choice. We hypothesized that versus BCT alone would result in decreased mortality.We performed 14-center, prospective observational patients who received during their resuscitation. applied generalized linear mixed-effects model random effect and controlled age,...

10.1097/sla.0000000000005603 article EN Annals of Surgery 2022-07-18
Nikolaos P. Daskalakis Artemis Iatrou Chris Chatzinakos Aarti Jajoo Clara Snijders and 95 more Dennis Wylie Christopher P. DiPietro Ioulia Tsatsani Chia‐Yen Chen Cameron D. Pernia Marina Soliva-Estruch Dhivya Arasappan Rahul Bharadwaj Leonardo Collado‐Torres Stefan Wuchty Victor E. Alvarez Eric B. Dammer Amy Deep–Soboslay Duc M. Duong Nicholas J. Eagles Bertrand R. Huber Louise A. Huuki-Myers Vincent Holstein Mark W. Logue Justina F. Lugenbühl Adam X. Maihofer Mark W. Miller Caroline M. Nievergelt Geo Pertea Deanna Ross Mohammad S.E. Sendi Benjamin B. Sun Ran Tao J. E. Tooke Erika J. Wolf Zane Zeier Sabina Berretta Frances A. Champagne Thomas M. Hyde Nicholas T. Seyfried Joo Heon Shin Daniel R. Weinberger Charles B. Nemeroff Joel E. Kleinman Kerry J. Ressler Caroline M. Nievergelt Adam X. Maihofer Elizabeth G. Atkinson Chia‐Yen Chen Karmel W. Choi Jonathan R. I. Coleman Nikolaos P. Daskalakis Laramie E. Duncan Renato Polimanti Cindy J. Aaronson Ananda B. Amstadter Søren Bo Andersen Ole A. Andreassen Paul A. Arbisi Allison E. Ashley‐Koch S. Bryn Austin Esmina Avdibegović Dragan Babić Silviu‐Alin Bacanu Dewleen G. Baker Anthony Batzler Jean C. Beckham Síntia Belangero Corina Benjet Carisa Bergner Linda M. Bierer Joanna M. Biernacka Laura J. Bierut Jonathan I. Bisson Marco P. Boks Elizabeth Bolger Amber Brandolino Gerome Breen Rodrigo A. Bressan Richard A. Bryant Angela C. Bustamante Jonas Bybjerg‐Grauholm Marie Bækvad‐Hansen Anders D. Børglum Sigrid Børte Leah Cahn Joseph R. Calabrese José Miguel Caldas‐de‐Almeida Chris Chatzinakos Sheraz Cheema Sean Clouston Lucía Colodro‐Conde Brandon J. Coombes Carlos S. Cruz-Fuentes Anders M. Dale Shareefa Dalvie Lea K. Davis Jürgen Deckert Douglas L. Delahanty Michelle F. Dennis

The molecular pathology of stress-related disorders remains elusive. Our brain multiregion, multiomic study posttraumatic stress disorder (PTSD) and major depressive (MDD) included the central nucleus amygdala, hippocampal dentate gyrus, medial prefrontal cortex (mPFC). Genes exons within mPFC carried most disease signals replicated across two independent cohorts. Pathways pointed to immune function, neuronal synaptic regulation, hormones. Multiomic factor gene network analyses provided...

10.1126/science.adh3707 article EN Science 2024-05-23

Background Up to 20–40% of survivors any traumatic injury develop post-traumatic stress disorder (PTSD) or depression after injury. Firearm may be at even higher risk for adverse outcomes. We aimed characterize PTSD and risk, pain symptoms, ongoing functional limitations in firearm early hospital discharge. Methods seen the Trauma Quality Life (TQOL) outpatient follow-up clinic 1–2 weeks discharge were invited participate a survey assessing both mental physical health The included Brief Pain...

10.1136/tsaco-2023-001336 article EN cc-by-nc-nd Trauma Surgery & Acute Care Open 2025-01-01

Outpatient follow-up represents a crucial opportunity to re-engage with gun violence survivors (GVS) and facilitate positive health outcomes. Current outpatient models for firearm-related injuries trauma care are inconsistent unstandardized across centers. This project describes the patient population served by multidisciplinary Trauma Quality of Life (TQoL) Clinic GVS. Also primary interest was services used patients prior their clinic appointment. Subsequent referrals placed during Clinic,...

10.1136/tsaco-2023-001199 article EN cc-by-nc-nd Trauma Surgery & Acute Care Open 2024-02-01

Persons of low socioeconomic status are overrepresented in the firearm injury patient population and may experience challenges accessing complex outpatient health systems. Consequently, care for these patients is plagued by poor follow-up increased emergency department (ED) utilization. We developed a Post Discharge Care Team (PDCT) consisting dedicated trauma nurse navigator medical social worker to bridge gap between hospital discharge improve recovery.

10.1097/ta.0000000000004299 article EN cc-by-nc-nd Journal of Trauma and Acute Care Surgery 2024-03-18

This project analyzed risk factors for emergency department (ED) utilization without readmission within 2 weeks post-discharge survivors of gun violence.

10.1136/tsaco-2023-001283 article EN cc-by-nc-nd Trauma Surgery & Acute Care Open 2024-06-01
Caroline M. Nievergelt Adam X. Maihofer Elizabeth G. Atkinson Chia‐Yen Chen Karmel W. Choi and 95 more Jonathan R. I. Coleman Nikolaos P. Daskalakis Laramie E. Duncan Renato Polimanti Cindy J. Aaronson Ananda B. Amstadter Søren Bo Andersen Ole A. Andreassen Paul A. Arbisi Allison E. Ashley‐Koch S. Bryn Austin Esmina Avdibegović Dragan Babić Silviu‐Alin Bacanu Dewleen G. Baker Anthony Batzler Jean C. Beckham Síntia Belangero Corina Benjet Carisa Bergner Linda M. Bierer Joanna M. Biernacka Laura J. Bierut Jonathan I. Bisson Marco P. Boks Elizabeth Bolger Amber Brandolino Gerome Breen Rodrigo A. Bressan Richard A. Bryant Angela C. Bustamante Jonas Bybjerg‐Grauholm Marie Bækvad‐Hansen Anders D. Børglum Sigrid Børte Leah Cahn Joseph R. Calabrese José Miguel Caldas‐de‐Almeida Chris Chatzinakos Sheraz Cheema Sean Clouston Lucía Colodro‐Conde Brandon J. Coombes Carlos Cruz-Fuentes Anders M. Dale Shareefa Dalvie Lea K. Davis Jürgen Deckert Douglas L. Delahanty Michelle F. Dennis Terri A. deRoon‐Cassini Frank Désarnaud Christopher P. DiPietro Seth G. Disner Anna R. Docherty Katharina Domschke Grete Dyb Alma Džubur Kulenović Howard J. Edenberg Alexandra Evans Chiara Fabbri Negar Fani Lindsay A. Farrer Adriana Feder Norah C. Feeny Janine D. Flory David Forbes Carol E. Franz Sandro Galea Melanie E. Garrett Bizu Gelaye Joel Gelernter Elbert Geuze Charles F. Gillespie Afërdita Goçi Slavina Goleva Scott D. Gordon Lana Ruvolo Grasser Camila Guindalini Magali Haas Saskia P. Hagenaars Michael A. Hauser Andrew C. Heath Sian MJ Hemmings Victor Hesselbrock Ian B. Hickie Kelleigh Hogan David M. Hougaard Hailiang Huang Laura M. Huckins Kristian Hveem Miro Jakovljević Arash Javanbakht Gregory D. Jenkins Jessica Johnson

Abstract Posttraumatic stress disorder (PTSD) genetics are characterized by lower discoverability than most other psychiatric disorders. The contribution to biological understanding from previous genetic studies has thus been limited. We performed a multi-ancestry meta-analysis of genome-wide association across 1,222,882 individuals European ancestry (137,136 cases) and 58,051 admixed with African Native American (13,624 cases). identified 95 significant loci (80 novel). Convergent...

10.1101/2023.08.31.23294915 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2023-09-02

BACKGROUND Psychological distress is common following a traumatic injury event. The Injured Trauma Survivor Screen (ITSS) was developed at level 1 trauma center to assess for posttraumatic stress disorder (PTSD) and major depressive episode (MDE) admission injury. ITSS sensitivity specificity were analyzed 3 6 9 months postinjury test the validity across centers. METHOD Four centers from East, Midwest, South, West in United States recruited 375 eligible adult inpatients (excluded...

10.1097/ta.0000000000003079 article EN Journal of Trauma and Acute Care Surgery 2021-04-02

Abstract Individuals who require hospitalization after traumatic injuries are at increased risk for developing posttraumatic stress disorder (PTSD); however, few early behavioral interventions have been effective preventing PTSD within this population. The aim of pilot study was to assess the feasibility and effectiveness modified prolonged exposure therapy (mPE) prevent depression symptoms among patients hospitalized a DSM‐5 single‐incident trauma. Hospitalized were eligible if they...

10.1002/jts.22580 article EN Journal of Traumatic Stress 2020-08-17

Early pelvic binder placement in the field stabilizes fractures and tamponades potential hemorrhage within pelvis. Despite known risk factors for fracture, it remains challenging to quickly triage correctly apply a binder. We aim develop prediction model that exclusively uses prehospital criteria inform decision place

10.1080/10903127.2023.2213316 article EN Prehospital Emergency Care 2023-05-12

Annually, approximately 27 million individuals in the United States are admitted to hospitals for emergency general surgery (EGS). Approximately 50% develop postoperative complications and 22% require unplanned readmission within 90 days, highlighting a need understand factors impacting well-being recovery. Psychiatric comorbidity can impact medical treatment adherence, cost, premature mortality risk. Despite severity of illness EGS, there is limited research on psychiatric EGS patients....

10.1136/tsaco-2023-001117 article EN cc-by-nc Trauma Surgery & Acute Care Open 2023-08-01

Objective: To investigate traumatic injury patient treatment preference for pharmacotherapy or psychotherapy to prevent post-injury development of posttraumatic stress disorder (PTSD).Method: This is a secondary analysis longitudinal cohort study traumatically injured patients (N = 198) at an urban Level 1 trauma center within 2 weeks injury.Results: Most participants preferred (80.8%) over pharmacotherapy. Preference did not differ by sex, mechanism injury, type perceived life threat during...

10.2139/ssrn.4733506 preprint EN 2024-01-01

ABSTRACT The COVID‐19 pandemic significantly impacted the psychological well‐being of general population. However, there are limited studies that examine its mental health effects on patients who have experienced traumatic injuries and tracked their recovery over time. This study aimed to: (1) compare rates severity post‐traumatic stress disorder (PTSD) depression between sustained before (pre‐pandemic) those injured during (peri‐pandemic); (2) assess whether degree pandemic‐related (e.g.,...

10.1002/smi.3513 article EN Stress and Health 2024-12-03

BACKGROUND: Trauma registries exist to provide data for evaluating the quality of care trauma patients. These facilitate research and can be used outreach, planning, improvement in patient outcomes. However, accuracy registry related suicide has not been well studied. OBJECTIVE: This study sought evaluate current coding practices labeling injury as a attempt among patients presenting Level I center after self-inflicted injury. METHODS: We conducted single-center, retrospective cohort...

10.1097/jtn.0000000000000739 article EN Journal of Trauma Nursing 2023-09-01
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