A5055244198- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- RNA Research and Splicing
- Radiomics and Machine Learning in Medical Imaging
- Epigenetics and DNA Methylation
- Reproductive System and Pregnancy
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Extracellular vesicles in disease
- Sperm and Testicular Function
- Phytoestrogen effects and research
- Cancer-related gene regulation
- RNA and protein synthesis mechanisms
- Inflammation biomarkers and pathways
- Colorectal and Anal Carcinomas
- Advanced Computational Techniques and Applications
- Reproductive Biology and Fertility
- Colorectal Cancer Screening and Detection
Sixth Affiliated Hospital of Sun Yat-sen University
2023
Sun Yat-sen University
2023
Shanghai East Hospital
2015-2021
Guangzhou Medical University
2018
Guangzhou First People's Hospital
2018
Tongji University
2005
MicroRNA-138 (miR-138) acts as a key regulator in the modulation of carcinogenesis numerous tumor types. Chemoresistance is common and relevant to failure multiple treatment strategies for cervical cancer. However, biological role miR-138 progression chemosensitivity cancer still unclear. The present study aimed investigate expression, function mechanism An mimic, inhibitor negative control were transfected into SiHa C33A cells. expression its target assessed by reverse transcription-PCR,...
The aim of the present study was to determine competitive endogenous RNA (ceRNA) network associated with long‑coding (lncRNA) LA16c‑313D11.11 in endometrial cancer (EC). Initially, expression levels 60 EC tissues, 20 atypical hyperplasia endometrium (EAH) tissues and normal determined. MicroRNA (miRNA/miR)‑205‑5p mimics were transfected into HEC‑1A Ishikawa cells. miR‑205‑5p, their target proteins assessed using reverse transcription‑quantitative PCR or western blot analysis. Flow cytometry,...
Neoadjuvant programmed cell death protein 1 (PD-1) blockade exhibits promising efficacy in patients with mismatch repair deficient (dMMR) colorectal cancer (CRC). However, discrepancies between radiological and histological findings have been reported the PICC phase II trial (NCT03926338). Therefore, we strived to discern features associated pathological complete response (pCR) based on computed tomography (CT) images. Data were obtained from that included 36 tumors 34 locally advanced dMMR...
Objective:The research paid close attention to the function of lncRNA-related endogenous competitive RNAs (ceRNAs) network in endometrial cancer (EC).Methods: 45 primary tissues (EC) and normal endometrium (NE) were included research.The online software StarbaseV2.0 was made use forecasting lncRNA which most likely contained microRNA-200c-3p combining sites could interact with microRNA-200c-3p.Subsequently, we chose lncRNAs consistent characteristics polyadenylation lower expression EC than...
Abstract Background Neoadjuvant chemotherapy (NCT) alone can achieve comparable treatment outcomes to chemoradiotherapy in locally advanced rectal cancer (LARC) patients. This study aimed investigate the value of texture analysis (TA) apparent diffusion coefficient (ADC) maps for identifying non-responders NCT. Methods retrospective included patients with LARC after NCT, and they were categorized into nonresponse group (pTRG 3) response 0–2) based on pathological tumor regression grade...
ABSTRACT Although platelet is anucleate cell, it contains a large amount miRNAs. This study aims to explore the relationship between miRNAs expression profles and platelets function, as well potential roles during storage lesions. Platelets were collected from 15 healthy men with O blood types. MiRNAs profiles in detected by Agilent Human miRNA Array Differential levels studied using human after apheresis stored for 2, 5 8 days microarray. There 167 230 altered day storage, respectively. In...