A5101787395- Pregnancy and preeclampsia studies
- Algal biology and biofuel production
- Birth, Development, and Health
- Heavy metals in environment
- Cervical Cancer and HPV Research
- Geochemistry and Geologic Mapping
- DNA Repair Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Pain Mechanisms and Treatments
- Air Quality and Health Impacts
- Gestational Diabetes Research and Management
- Acupuncture Treatment Research Studies
- Regulation of Appetite and Obesity
- Genomic variations and chromosomal abnormalities
- Wastewater Treatment and Nitrogen Removal
- Pregnancy-related medical research
- Nanoparticles: synthesis and applications
- Pharmaceutical and Antibiotic Environmental Impacts
- Adenosine and Purinergic Signaling
- Molecular Biology Techniques and Applications
- Electrokinetic Soil Remediation Techniques
- Microbial bioremediation and biosurfactants
- Environmental and Social Impact Assessments
- Coal and Its By-products
- Graphene and Nanomaterials Applications
Hubei University of Technology
2023-2025
Wuhan University
2023-2025
Zhejiang Chinese Medical University
2020-2023
Hangzhou Hospital of Traditional Chinese Medicine
2023
Ministry of Ecology and Environment
2022
Women's Hospital, School of Medicine, Zhejiang University
2006-2019
Ministry of Education of the People's Republic of China
2016
Gestational diabetes mellitus (GDM) is an important complication of pregnancy that poses significant threats to women and their offspring. Telomere length shortens as cellular damage increases associated with metabolic diseases. in fetal leucocytes was determined 82 infants GDM (N = 82) 65 normal pregnant 65). Women preeclampsia 45) gestational hypertension 23) were also studied. In the group, telomere significantly shorter than (P 0.028), but there no differences between 0.841) 0.561)....
In this study, we compared the concentrations of heavy metals Cd, Cr, Cu, Zn, Ni, and Pb in surface soils urban parks Wuhan, Hubei Province, with those worldwide. The soil contamination data were assessed using enrichment factors spatial analysis inverse distance weighting quantitative metal sources a positive definite matrix factor (PMF) receptor model. Further, probabilistic health risk assessment children adults Monte Carlo simulation was performed. average 2.52, 58.74, 31.39, 186.28,...
Abstract Objectives . To characterise the changes in serum visfatin levels late normal pregnancy and pre‐eclampsia. Methods Twenty‐seven women with pre‐eclampsia were recruited. Twenty‐eight third trimester of served as pregnant control 28 healthy non‐pregnant control. Serum measured an enzyme‐linked immunosorbent assay. Results The means 626.4±45.5ng/ml (mean±SEM) control, 695.9±92.5ng/ml 308.3±80.0 ng/ml pre‐eclampsia, respectively, significantly different among groups ( p <0.001)....
Abstract Diabetic neuropathic pain (DNP) is a troublesome diabetes complication all over the world. P2X3 receptor (P2X3R), purinergic from dorsal root ganglion (DRG), has important roles in pathology and nociceptive sensations. Here, we investigated involvement of DRG P2X3R effect 2 Hz electroacupuncture (EA) on DNP. We monitored rats’ body weight, fasting blood glucose level, paw withdrawal thresholds, latency, evaluated expression DRG. found that upregulated DNP, while EA analgesic against...
Objectives. To verify the hypothesis that vascular endothelial growth factor (VEGF) attenuates Nω-Nitro-L-arginine Methyl Ester (L-NAME)-induced preeclampsia-like manifestations in rats. Study design. Forty pregnant Wistar rats were randomly divided into four groups: control, preeclampsia model, VEGF treatment, and prophylactic. On day 5 of gestation, L-NAME was injected subcutaneously prophylactic groups. given after occurrence hypertension proteinuria treatment group from group. Blood...
Prenatal tobacco exposure (PTE) correlates significantly with a surge in adverse pregnancy outcomes, yet its pathological mechanisms remain partially unexplored. This study aims to meticulously examine the repercussions of PTE on placental immune landscapes, employing coordinated research methodology encompassing bioinformatics, machine learning and animal studies. Concurrently, it screen biomarkers potential compounds that could sensitively indicate mitigate disorders. In course this...
The aim of this case-control study was to clarify the relationship between uracil N-glycosylase (UNG) rs3219218 and rs246079 genotypes risk cervical squamous cell cancer (CSCC). Modified polymerase chain reaction-mismatch amplification (MA-PCR) applied for genotyping UNG (A/G) polymorphisms in 400 CSCC, intraepithelial neoplasia (CIN) III, 1200 normal controls. We observed no association polymorphism CIN III or CSCC. However, (odds ratio [OR] = 1.58) CSCC (OR 2.08) significantly increased...
This study was performed to investigate the relationship between MUTYH Gln324His (CAG/CAC) genotype and risk of cervical squamous cell carcinoma (CSCC) in a case-control setting. Mismatch amplification-polymerase chain reaction (MA-PCR) applied detect polymorphism 400 CSCC, CIN III 1200 control participants. The homozygous His324His (CAC/CAC) associated with significantly increased (OR = 1.94) CSCC 3.83). Increased 1.34) 1.97) additionally observed heterozygous CAG/CAC genotype. Overall,...
The aim of this study was to investigate the application amniotic fluid cell lines with chromosomal abnormalities in external quality assessment (EQA) prenatal karyotype analysis. Simian virus 40 large T antigen (SV40LT) gene transfected into cells 46,XY,t(15;17)(q11;q11) and 46,XY by liposome transfection. Control were produced mixing above two ratios 1:19, 1:1 9:1, respectively. then frozen at −30 °C, mailed between laboratories, prepared for chromosome analysis, photographed karyotype,...
Abstract Management of diabetic neuropathic pain (DNP), a prevalent, refractory complication, remains challenge. Previous research evidences have implicated microglia P2X4 receptor (P2X4R) in occurrence and development DNP. To date, however, the specific mechanism P2X4R action DNP needs to be further explored. We elucidated role underlying The rat model was established by injection streptozotocin (STZ). rats developed thermal hyperalgesia from day 14. Western blot immunofluorescence analyse...