A5049063345- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Knee injuries and reconstruction techniques
- Esophageal Cancer Research and Treatment
- Orthopedic Infections and Treatments
- Gastric Cancer Management and Outcomes
- Osteoarthritis Treatment and Mechanisms
- Lung Cancer Treatments and Mutations
- Neuroscience and Neuropharmacology Research
- Ion channel regulation and function
- Orthopedic Surgery and Rehabilitation
- Tribology and Wear Analysis
- Tendon Structure and Treatment
- Lower Extremity Biomechanics and Pathologies
- Hip disorders and treatments
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Head and Neck Cancer Studies
- Bone health and osteoporosis research
- Cellular Mechanics and Interactions
- Colorectal Cancer Surgical Treatments
- Neural dynamics and brain function
- Nicotinic Acetylcholine Receptors Study
- Diverticular Disease and Complications
- Cholangiocarcinoma and Gallbladder Cancer Studies
Kyushu Rosai Hospital
2011-2024
Osaka University
1986-2020
Kyushu University
1969-2012
Yale University
2006-2012
Tokyo Medical and Dental University
1993-2009
Kyushu Hospital
2005
Kyushu University Hospital
2004
Kyoto Institute of Technology
2002
Kyushu Sangyo University
2002
Wesleyan University
1998
Fluorescent dyes which are specific for duplex DNA have found a wide range of applications from staining gels to visualization chromosomes. Porphyrin been highly fluorescent in the presence quadruplex but not DNA. These may offer route detection under biologically important conditions. There three types structures, and these play roles telomere, centromere, triplet repeat, integration sites other DNAs, this first set porphyrin show some selectivity between types.
Background: The incidence of developmental dysplasia the hip (DDH) in Japanese newborns has reduced drastically following a primary prevention campaign initiated around 1972 to 1973; this perinatal education promoted maintaining hips naturally flexed-leg position. purpose present study was describe life course epidemiology osteoarthritis (OA) adolescent and adult patients assess its association with exposure for DDH. Methods: We included new OA diagnosed from January 1, 2022, December 31, at...
To examine in vivo the effects of a mixture high molecular weight hyaluronic acid (HA) plus phospholipids on joint lubrication and articular cartilage degeneration.Experimental osteoarthritis (OA) right knee was induced by anterior cruciate medial collateral ligament transection 40 rabbits. The animals were subjected to 8 consecutive weekly intraarticular administrations HA (the HA200 group), conventional HA80 or L-delta dipalmitoyl phosphatidylcholine liposomes PHA group) killed 1 week...
Abstract Dipalmitoyl phosphatidylcholine, a highly surface‐active polar lipid, has been implicated as potential boundary lubricant for synovial joints. We examined the effects of dipalmitoyl phosphatidylcholine on flexor tendon and its protective effect against postoperative adhesion in two experimental steps. First, digitorum fibularis distal pulley rabbits were set friction test. The test was performed with saline solution, sodium hyaluronate, or mixture hyaluronate lubricant. coefficient...
Our study evaluated the accuracy of an image-guided total knee replacement system based on CT with regard to preparation femoral and tibial bone using nine limbs from five cadavers. The was assessed by direct measurement extramedullary alignment rod without radiographs. mean angular errors femur tibia, which represent gaps real mechanical axis in coronal plane, were 0.3° 1.1°, respectively. CT-based system, provided almost perfect component less than 1° error excellent 3° for component....
Patellar tracking and femoral condylar geometry in deep knee flexion were evaluated using magnetic resonance imaging. The patellar tilting angle, shift, anteroposterior translation from 0° to 135° measured. depth of the articular surface curvature also measured at flexion. patella shifted laterally, tilted medially, sank deeply into intercondylar notch during lateral condyle, existing within notch, began curve steeply a point farther center than did medial condyle. condyle is adequate fit...
The polypeptides of mouse B16 melanoma lines defined metastatic potential have been analyzed by two-dimensional electrophoresis.Parent and two independently isolated B16-F1 lines, which are low metastatic, exhibited a new polypeptide, A" (PI 5.2; M, = 43,000), comprising approximately 30% the total actin, in addition to normal 8and yactin.The is present Triton-insoluble fraction (cytoskeleton nuclear matrix) as well Triton-soluble at constant ratio about 0.5 8plus y-actin.The polypeptide has...
Colony-stimulating factor-1 (CSF-1) promotes the survival of osteoclasts, short-lived cells that resorb bone. Although a rise in intracellular pH (pH(i)) has been linked to inhibition apoptosis, effect CSF-1 on pH(i) osteoclasts not reported. The present study shows that, absence CO(2)/HCO(3)(-), causes little change osteoclast pH(i). In contrast, exposing these presence CO(2)/HCO(3)(-) rapid and sustained cellular alkalinization. CSF-1-induced is blocked by...
Endoscopic resection is curative for superficial esophageal squamous cell carcinoma (ESCC) limited to the lamina propria. not recommended ESCC invading muscularis mucosa or submucosa, however, because of high frequency lymph node metastasis (LNM) in such patients. Methods more accurately predict LNM by analysis endoscopically resected specimens are needed. Patients with who underwent surgery without prior chemoradiotherapy (n= 110) were retrospectively examined determine whether correlated...
PURPOSE: To determine the accuracy of 4.7-T magnetic resonance (MR) imaging for evaluating mural invasion esophageal carcinoma. MATERIALS AND METHODS: Sixty-seven specimens containing 70 squamous cell carcinomas were studied with a MR system 4-cm-diameter surface coil. Spin-echo images obtained field view 4-6 cm, matrix size 256 x 256, and section thickness 3 mm, which resulted in voxel 0.08-0.16 mm3. findings compared histopathologic findings, served as standard reference. Tumor on was...
Background : Epstein-Barr virus (EBV) has been detected in about 10% of gastric carcinoma cases worldwide, and a high prevalence EBV involvement remnant reported recently. Details the background stomach EBV-positive lesions, however, have not well clarified. Methods We screened 17 consecutive lesions resected surgically. To detect EBV, we used situ hybridization (ISH) for EBV-encoded small RNA1 (EBER-1) compared clinicopathologic feature between and-negative cases. Results was 41.8% (7 17)...
The purpose of this study was to evaluate the influence patient age on effects conservative treatment anterior cruciate ligament (ACL).A total 102 consecutive patients with acute ACL injury were allowed heal without surgery. Final magnetic resonance imaging images classified from grade I, indicating good morphological recovery, IV, poor recovery. Chi-square analysis used determine significant differences in incidence grades I and II among those less than 20 versus years or more age.The mean...
Background: It is often difficult to evaluate the posterior aspects of femoral condyles after total knee arthroplasty. We have developed an imaging technique involving use oblique condylar view for evaluation condyles. The purpose present study was compare efficacy this with that true-lateral view. Methods: Three orthopaedic surgeons analyzed fifty-five sets radiographs (consisting and views) patients who had undergone accuracy reproducibility detection radiolucencies were compared those...
PTH is the only currently available anabolic therapy for osteoporosis. In clinical practice, skeletal response to varies and because limited 2 yr, approaches maximize therapeutic are desirable. Rac2 a small GTPase that expressed in hematopoietic tissue. Rac2(-/-) mice have slight increase bone mass osteoclasts isolated from these animals reduced basal resorptive activity chemotaxis. To evaluate mice, we treated 18 17 control, age-matched wild-type once daily 28 d with 80 ng/g body weight of...
In patients with chronic pain, oral analgesics are essential treatment options to manage pain appropriately, improve activities of daily living abilities and achieve a higher quality life (QOL). It is desirable select for elderly based on comparative data analgesic effect risk adverse events; however, there few studies so far. The purpose this study determine whether the efficacy safety acetaminophen non-inferior non-steroidal anti-inflammatory drugs (NSAIDs) in associated osteoarthritis hip...