A5101955783- Helicobacter pylori-related gastroenterology studies
- Mycobacterium research and diagnosis
- Cancer-related molecular mechanisms research
- COVID-19 Clinical Research Studies
- Pancreatitis Pathology and Treatment
- Plasma Applications and Diagnostics
- Magnetism in coordination complexes
- Metal complexes synthesis and properties
- Catalytic Processes in Materials Science
- MicroRNA in disease regulation
- Gastric Cancer Management and Outcomes
- Autophagy in Disease and Therapy
- Plasma Diagnostics and Applications
- Microscopic Colitis
- Eosinophilic Esophagitis
- Colorectal Cancer Treatments and Studies
- COVID-19 Impact on Reproduction
- Gastrointestinal disorders and treatments
- Colorectal and Anal Carcinomas
- Curcumin's Biomedical Applications
- Melanoma and MAPK Pathways
- Telomeres, Telomerase, and Senescence
- Carbohydrate Chemistry and Synthesis
- Ginseng Biological Effects and Applications
- Abdominal Surgery and Complications
Waseda University
2020-2025
Shandong First Medical University
2017-2024
Nanchang University
2020-2024
Chinese Academy of Sciences
2013-2024
First Affiliated Hospital of Jiangxi Medical College
2024
Hefei Institutes of Physical Science
2023-2024
First Affiliated Hospital of Nanchang University
2020-2023
Yunnan University
2023
Ministry of Education of the People's Republic of China
2023
Shanxi University of Traditional Chinese Medicine
2023
Intestinal dysfunction is one of the common complications in early stage acute pancreatitis (AP), which often associates with bad outcome. Lactulose, as a prebiotic, has been widely used to improve gut health, yet its effect on AP unclear. This was prospective, randomized trial moderate severe patients complicated intestinal dysfunction. A total 73 participants were randomly assigned receive either lactulose or Chinese herb rhubarb for 1 week. The primary efficacy endpoint recovery function....
ABSTRACT Spermine (SPM) and spermidine (SPD) are polyamines found in all organisms, their concentrations can be regulated by ingestion. We demonstrated that yeast‐fermented garlic (YF) extract significantly increased autophag flux OUMS‐36T‐1 HeLa cells expressing the fluorescent probe (GFP‐LC3‐RFP‐LC3ΔG). YF‐induced increase of autophagy occurred independently mTORC1 signaling, RNA‐sequencing analysis revealed EGR1 was most altered gene YF‐treated cells. EGR1‐ deficient HAP1 displayed...
This study is dedicated to the design and synthesis of novel yellow-emitting Cu(I) complex enantiomers, R/S-Phen-Cu-POP, where center chelated by chiral 1,1'-binaphthalene-functionalized 1,10-phenanthroline (Phen) bis(2-diphenylphosphinophenyl)ether (POP). Photophysical characterization revealed that quantum yield (Φem) R/S-Phen-Cu-POP in CH2Cl2 solutions was only 1.4-1.6%, but it significantly increased 73.0% (R) 76.1% (S) PMMA doping films. Circularly polarized luminescence (CPL) studies...
The aim of the present study was to examine dynamic expression matrix metalloproteinase (MMP)‑2, MMP‑9 and MMP‑13 in an ovariectomy (OVX)‑induced osteoporosis rat model. A total 80 Sprague‑Dawley female rats (age, 3 months) were randomly divided into OVX sham groups, with 40 each group. Rats group received surgery, while remaining ovariectomized. After 12, 16, 20 24 weeks, 10 from sacrificed, respectively. It observed that bone mineral density (BMD) trabecular area significantly lower as...
The reaction of bis- or tris-chelating nitrogen-containing ligands (L1-L5) with CuI gave rise to five coordination complexes consisting Cu2 I2 dimeric units. L1 in complex 1 adopts a cis conformation and links into dinuclear structure. L2 L3 2 3 exhibit trans conformation, the alternative linkage results formation 1D chain. In 4, two pyrazolyl-pyridine units L4 at same side central phenyl ring are connected forming tetranuclear macrocycle, third unit other further macrocycle L5 bridges...
The present study aimed to examine the role and underlying mechanism of miRNA-758 (miR-758) expression in cancer tissues, blood cervical exfoliated cells from patients with cancer. A total 49 26 healthy people for screening were included study. treated resection, tumor adjacent collected. levels miR-758 matrix extracellular phosphoglycoprotein (MEPE) mRNA each sample detected by reverse transcription-quantitative polymerase chain reaction. In addition, western blot analysis was used detect...
Gastrointestinal (GI) dysfunction is a common and important complication of acute pancreatitis (AP), especially in patients with severe AP. Despite this, there no consensus means obtaining precise assessment GI function.To determine the association between gastrointestinal injury (AGI) grade clinical outcomes critically ill AP.Patients AP admitted to our pancreatic intensive care unit from May 2017 2019 were enrolled. function was assessed according AGI proposed by European Society Intensive...
Background: Colon adenocarcinoma (COAD), a malignant gastrointestinal tumor, has the characteristics of high mortality and poor prognosis. Even in presence oxygen, Warburg effect, major metabolic hallmark almost all cancer cells, is characterized by increased glycolysis lactate fermentation, which supports biosynthesis provides energy to sustain tumor cell growth proliferation. However, thorough investigation into glycolysis- lactate-related genes their association with COAD prognosis,...
Background: The basement membrane (BM) serves as a major barrier to impede tumor cell invasion and extravasation during metastasis. However, the associations between BM-related genes GC remain unclear. Methods: RNA expression data corresponding clinical information of STAD samples were downloaded from TCGA database. We identified subtypes constructed gene prognostic model using lasso-Cox regression analysis. also investigated single-cell properties prognostic-related TME characteristic, TMB...
BackgroundHelicobacter pylori (H. pylori) biofilm formation is a key factor in refractory H. infection. The aim of this study was to understand research trends biofilms.MethodsThe Web Science Core Collection database used retrieve publications published from 1998 2023. Different kinds software, EXCEL, an online bibliometric analysis platform, and the VOS viewer were evaluate visualize data.ResultsIn total, 184 identified, number increased annually. USA made greatest contributions field,...
Objective Ghrelin is a protein that regulate appetite and energy balance in the human body, which encoded by ghrelin prepropeptide gene (GHRL). GHRL linked with carcinogenesis immune regulation. However, correlation of to prognosis tumor-infiltrating lymphocytes gastric cancer (GC) remains unclear. Methods In this study, we assessed transcriptional expression, prognosis, different clinicopathological features about between tumor infiltration cells GC patients based on data published...
Excessive alcohol consumption can cause multi-systemic diseases. Among them, alcoholic liver disease is the most frequent and serious disease. Electrolytic hydrogen water (EHW) produced at cathode during electrolysis of contains a large amount molecular low content platinum nanoparticles with alkaline properties. In this study, we found that EHW inhibits ethanol-induced cytotoxicity by decreasing intracellular acetaldehyde, toxic substance ethanol degradation, in hepatocyte cell lines HepG2....
Current evidence on the associations between plasma thyroid stimulating hormone and Helicobacter pylori infection is conflicting. Therefore, our study aimed to examine TSH in relation H. infection.Based US National Health Nutrition Examination Survey (NHANES) 1999-2000, a cross-sectional was conducted with 948 participants aged 30 85 years. The seropositivity were evaluated using binary logistic regression models. A subgroup analysis stratified by sex, age, body mass index conducted.A higher...
To investigate the risk factors of radiation enteritis in patients with cervical cancer after radiotherapy.Retrospective analysis 90 receiving therapy from January 2019 to May 2021 Hefei Cancer Hospital, Chinese Academy Sciences. The were divided into group and control according enteritis, continuous variable analyzed by ROC obtain best truncation value, univariate multifactorial logistic regression models independent for patients. Nomogram was constructed evaluated based on factors.The...
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Currently, the available evidence regarding relationship between lipid profile and Helicobacter pylori (H. pylori) infection is limited conflicting. There also a dearth of studies that have explored possibility sex-specific differences in association H. triglyceride levels.We conducted cross-sectional study involving 1,146 participants utilizing data from National Health Nutrition Examination Survey (NHANES) 1999-2000 United States. A logistic regression model was employed to evaluate...
The present study aimed to investigate the molecular mechanisms of microRNA (miR)‑181b in heart disease due hypertensive disorders complicating pregnancy (HDCP) through regulating expression metallopeptidase inhibitor 3 (TIMP3). miR‑181b was detected by reverse transcription‑quantitative polymerase chain reaction peripheral blood samples from patients with HDCP. These were analyzed for clinical pathological characteristics. primary cardiomyocytes rats cultured hypoxic conditions 24 h, which...
Colon adenocarcinoma (COAD) is a frequent malignancy of the digestive system with poor prognosis and high mortality rate worldwide. Intratumor heterogeneity (ITH) associated tumor progression, prognosis, immunosuppression, therapy resistance. However, relationship between ITH immune microenvironment, chemotherapy response in COAD patients remains unknown, this knowledge urgently needed. We obtained clinical information gene expression data for from The Cancer Genome Atlas (TCGA) database....