A5042382869- Cardiac Arrest and Resuscitation
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Disease and Adiposity
- Ultrasound in Clinical Applications
- Cardiac Structural Anomalies and Repair
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Eicosanoids and Hypertension Pharmacology
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiovascular Effects of Exercise
- Alcohol Consumption and Health Effects
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Opioid Use Disorder Treatment
- Acute Myocardial Infarction Research
- Fatty Acid Research and Health
- Cardiovascular Health and Disease Prevention
- Heart Rate Variability and Autonomic Control
- Cardiac electrophysiology and arrhythmias
- Cardiac Health and Mental Health
- Mechanical Circulatory Support Devices
Clinique Ambroise Paré
2007-2024
Hôpital Civil, Strasbourg
2024
Université de Strasbourg
2024
Société Française de Cardiologie
2023
Hôpital Broussais
1996-1997
Hôpital Ambroise-Paré
1995-1997
Hôpitaux Universitaires Henri-Mondor
1997
Abstract Aims Impact of skin mottling has been poorly studied in patients admitted for cardiogenic shock. This study aimed to address this issue and identify determinants 30-day 1-year mortality a large shock cohort all etiologies. Methods results FRENSHOCK is prospective multicenter observational registry conducted French critical care units between April October, 2016. Among the 772 enrolled (mean age 65.7 ± 14.9 years; 71.5% male), 660 had assessed at admission (85.5%) with almost 39%...
Abstract Aims Since the introduction of direct oral anticoagulant (DOAC) for atrial fibrillation (AF) therapy, inappropriate and/or underdosing these drugs has been a major clinical challenge. We evaluated characteristics patients with AF treated and low-dose DOACs. Methods results Patients DOACs from October 2021 to December were French National Prospective Registry (PAFF). 1890 receiving (apixaban 55%, dabigatran 7%, rivaroxaban 38%). Inappropriate dosing was noted in 18% population....
Takotsubo cardiomyopathy (TTC) is a rare entity after cardiac surgery.To describe patients' profile who developed postoperative TTC surgery, management, and outcomes.We performed systematic literature search to extract cases of adult surgery (from 1990 2021). Additionally, we extracted all in prospective single-center cohort database 10,000+ patients 2007 2019). We then combined single its clinical features.From 694 screened articles, retained 71 individual published 20 distinct articles (19...
BackgroundSmoking cigarettes produces carbon monoxide (CO), which can reduce the oxygen-carrying capacity of blood. We aimed to determine whether elevated expiratory CO levels would be associated with a worse prognosis in smokers presenting acute cardiac events.MethodsFrom 7 22 April 2021, were measured prospective registry including all consecutive patients admitted for event 39 centres throughout France. The primary outcome was 1-year all-cause death. Initial in-hospital major adverse...
Abstract Background Despite scarce data, invasive mechanical ventilation (MV) is widely suggested as first-line ventilatory support in cardiogenic shock (CS) patients. We assessed the real-life use of different strategies CS and their influence on short mid-term prognosis. Methods FRENSHOCK was a prospective registry including 772 patients from 49 centers France. Patients were categorized into three groups according to supports during hospitalization: no group (NV), non-invasive alone (NIV),...
We report a case of acute myocardial infarction occurring in patient with severe aortic stenosis and left ventricular hypertrophy. A coronary angiogram performed during the phase evolving excluded obstruction as cause this patient.
Abstract Background Tricuspid annular plane systolic excursion over pulmonary artery pressure (TAPSE/sPAP) assessed by echocardiography is a good non-invasive approach for right ventricular to (RV-PA) coupling assessment. Although the prognostic value of this ratio well known in many cardiovascular diseases, its acute coronary syndrome (ACS) not established. Purpose To assess one-year TAPSE/sPAP among patients hospitalised ACS. Methods In prospective multicentric ADDICT-ICCU study, all...
Background: A new ESC guidelines in 2023, the International Lipid Expert Panel (ILEP) 2021 recommendations, and a subsequent statement by EAS have been published based on recent advances lipid lowering treatments. However, real world data are lacking regarding implementation among community of French cardiologists. Objective: To determine current approach therapeutic strategies concerning treatments post-acute coronary syndromes France. Methods: This national survey was performed during...
Although some scores based on traditional statistical methods are available for risk stratification in patients hospitalized cardiac intensive care units (CICUs), the interest of machine learning (ML) this field is not well established. We aimed to build an ML model predict in-hospital major adverse events (MAE) CICU. In April 2021, a French national prospective multicentre study involving 39 centres included all consecutive admitted The primary outcome was MAE, including death, resuscitated...
Background: Smoking cigarettes produces carbon monoxide (CO), which can reduce the oxygen-carrying capacity of blood. We aimed to determine whether elevated expiratory CO levels would be associated with a worse prognosis in smokers presenting acute cardiac events.Methods: Expiratory were measured consecutive patients admitted for prospective study. The primary outcome was 1-year all-cause death. Initial in-hospital major adverse events (MAEs; death, resuscitated arrest and cardiogenic shock)...
We determined eligibility for icosapent ethyl (EPA) treatment in coronary artery disease (CAD).Consecutive patients with type 2 diabetes and CAD were prospectively included from 03/2019 to 12/2020.574 included; mean age 71 years, 81% males, a high prevalence of other risk factors (81% hypertension). Mean lipid-density lipoprotein cholesterol was 85 mg/dl, glycated hemoglobin HbA1c 7.1%, triglycerides 148 mg/dl; 82% received statins. Based on National Lipid Association criteria, 31% would be...
Hydrogen sulfide is produced endogenously by a variety of enzymes involved in cysteine metabolism.Clinical data indicate that endogenous levels hydrogen are diminished various forms cardiovascular diseases.The aim the current study was to investigate effects supplementation on cardiac function during reperfusion clinically relevant experimental model cardiopulmonary bypass.Twelve anesthetized dogs underwent hypothermic bypass.After 60 minutes arrest, started after application either saline...